PMID- 30952524
OWN - NLM
STAT- MEDLINE
DCOM- 20200708
LR  - 20200708
IS  - 1879-0828 (Electronic)
IS  - 0953-6205 (Linking)
VI  - 63
DP  - 2019 May
TI  - The fat-to-lean mass ratio, a novel anthropometric index, is associated to 
      glucose metabolic disorders.
PG  - 74-78
LID - S0953-6205(19)30106-2 [pii]
LID - 10.1016/j.ejim.2019.03.017 [doi]
AB  - OBJECTIVE: The aim was to evaluate whether the Fat-to-Lean Mass (FyM) ratio is 
      associated to glucose metabolic disorders (GMD). DESIGN: Cross-sectional 
      population based study. METHODS: Eligible subjects were healthy men and 
      non-pregnant women with new diagnosis of GMD that were allocated into following 
      groups: 1) Normal Glucose Tolerance (NGT), 2) Diabetes, 3) impaired fasting 
      glucose (IFG) + impaired glucose tolerance (IGT), 4) IGT, and 5) IFG. The FyM 
      index [Total body fat (Kg)/total lean mass (Kg)], and the odds ratio (OR) between 
      FyM index and GMD were estimated. RESULTS: A total of 875 individuals with 
      average age 41.62 +/- 12.3 were enrolled; of them, 645 (73.1%) women and 230 
      (22.8%) men; 521 (59.5%), 71 (8.1%), 85 (9.7%), 53 (6.0%), and 145 (16.6%) 
      individuals were allocated into groups with NGT, diabetes, IFG + IGT, IGT, and 
      IFG, respectively. The FyM was significantly associated with prediabetes and 
      diabetes in women (OR 4.2; (95%)CI 3.0-11.1 and OR = 7.2; (95%)CI 2.0-15.2) and 
      men (OR = 2.6; (95%)CI 1.1-6.7 and OR = 4.6; (95%)CI 1.4-15.1). In the overall 
      population, the OR between FyM index with IGT, IFG, and IFG + IGT was 8.4 
      ((95%)CI 2.6-17.4), 5.2 ((95%)CI 2.6-10.6), and 6.1 ((95%)CI 1.8-9.5). 
      CONCLUSION: The FyM index was strongly associated with all categories of GMD.
CI  - Copyright (c) 2019. Published by Elsevier B.V.
FAU - Gamboa-Gomez, Claudia I
AU  - Gamboa-Gomez CI
AD  - Biomedical Research Unit of the Mexican Social Security Institute at Durango, 
      Mexico.
FAU - Simental-Mendia, Luis E
AU  - Simental-Mendia LE
AD  - Biomedical Research Unit of the Mexican Social Security Institute at Durango, 
      Mexico.
FAU - Rodriguez-Moran, Martha
AU  - Rodriguez-Moran M
AD  - Biomedical Research Unit of the Mexican Social Security Institute at Durango, 
      Mexico.
FAU - Guerrero-Romero, Fernando
AU  - Guerrero-Romero F
AD  - Biomedical Research Unit of the Mexican Social Security Institute at Durango, 
      Mexico. Electronic address: guerrero.romero@gmail.com.
LA  - eng
PT  - Journal Article
DEP - 20190402
PL  - Netherlands
TA  - Eur J Intern Med
JT  - European journal of internal medicine
JID - 9003220
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Adipose Tissue/*physiopathology
MH  - *Adiposity
MH  - Adult
MH  - Anthropometry
MH  - Blood Glucose
MH  - Body Mass Index
MH  - Cross-Sectional Studies
MH  - Female
MH  - Glucose Intolerance
MH  - Glucose Metabolism Disorders/classification/*diagnosis/physiopathology
MH  - Glucose Tolerance Test
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Muscle, Skeletal/*physiopathology
OTO - NOTNLM
OT  - Fat
OT  - Impaired fasting glucose
OT  - Impaired glucose tolerance
OT  - Muscle
OT  - Type 2 diabetes
EDAT- 2019/04/07 06:00
MHDA- 2020/07/09 06:00
CRDT- 2019/04/07 06:00
PHST- 2018/07/17 00:00 [received]
PHST- 2019/01/21 00:00 [revised]
PHST- 2019/03/28 00:00 [accepted]
PHST- 2019/04/07 06:00 [pubmed]
PHST- 2020/07/09 06:00 [medline]
PHST- 2019/04/07 06:00 [entrez]
AID - S0953-6205(19)30106-2 [pii]
AID - 10.1016/j.ejim.2019.03.017 [doi]
PST - ppublish
SO  - Eur J Intern Med. 2019 May;63:74-78. doi: 10.1016/j.ejim.2019.03.017. Epub 2019 
      Apr 2.