PMID- 30956576 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 0899-8280 (Print) IS - 1525-3252 (Electronic) IS - 0899-8280 (Linking) VI - 32 IP - 1 DP - 2019 Jan TI - Predictors and prognosis of no-reflow during primary percutaneous coronary intervention. PG - 30-33 LID - 10.1080/08998280.2018.1509577 [doi] AB - The no-reflow phenomenon occurs in a considerable number of patients with ST elevation myocardial infarction (STEMI) undergoing primary reperfusion therapy. Our study aimed to identify clinical, angiographic, and procedural variables that predict this phenomenon in patients with STEMI undergoing primary percutaneous coronary intervention (PPCI), as well as determine the impact of no-reflow on in-hospital mortality. Prospective observational data from 410 patients with STEMI undergoing PPCI were obtained. In this study, diabetes mellitus, late presentation, higher Killip class at admission, anterior wall infarction, proximal site of occlusion, presence of high-grade thrombus, and left ventricular systolic dysfunction at admission were significantly associated with suboptimal coronary flow. Diabetes mellitus, a high thrombus burden, prolonged total ischemic time, and low left ventricular ejection fraction on admission were independent predictors of no-reflow. No-reflow during PPCI was associated with in-hospital mortality more than twice that for normal flow. FAU - Nair Rajesh, Govindan AU - Nair Rajesh G AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - Jayaprasad, Narayanapillai AU - Jayaprasad N AUID- ORCID: 0000-0002-1674-339X AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - Madhavan, Suresh AU - Madhavan S AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - Sudha Kumary, Vasantha AU - Sudha Kumary V AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - Jayaprakash, Kesavapillai AU - Jayaprakash K AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - Raihanathul Misiriya, Kamarudheenkunju Jameelabeevi AU - Raihanathul Misiriya KJ AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - Jayaprakash, Vaikathusseril Lembodaran AU - Jayaprakash VL AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. FAU - George, Raju AU - George R AD - Department of Cardiology, Government Medical CollegeKottayamKeralaIndia. LA - eng PT - Journal Article DEP - 20181227 PL - United States TA - Proc (Bayl Univ Med Cent) JT - Proceedings (Baylor University. Medical Center) JID - 9302033 PMC - PMC6442883 OTO - NOTNLM OT - Myocardial infarction OT - no-reflow OT - predictors OT - primary percutaneous intervention EDAT- 2019/04/09 06:00 MHDA- 2019/04/09 06:01 PMCR- 2018/12/27 CRDT- 2019/04/09 06:00 PHST- 2018/05/17 00:00 [received] PHST- 2018/07/30 00:00 [revised] PHST- 2018/08/06 00:00 [accepted] PHST- 2019/04/09 06:00 [entrez] PHST- 2019/04/09 06:00 [pubmed] PHST- 2019/04/09 06:01 [medline] PHST- 2018/12/27 00:00 [pmc-release] AID - 1509577 [pii] AID - 10.1080/08998280.2018.1509577 [doi] PST - epublish SO - Proc (Bayl Univ Med Cent). 2018 Dec 27;32(1):30-33. doi: 10.1080/08998280.2018.1509577. eCollection 2019 Jan.