PMID- 30965158
OWN - NLM
STAT- MEDLINE
DCOM- 20191209
LR  - 20221207
IS  - 1877-0665 (Electronic)
IS  - 1877-0657 (Linking)
VI  - 62
IP  - 3
DP  - 2019 May
TI  - Sensitivity to change and minimal clinically important difference of the 
      Locomotor Capabilities Index-5 in people with lower limb amputation undergoing 
      prosthetic training.
PG  - 137-141
LID - S1877-0657(19)30034-X [pii]
LID - 10.1016/j.rehab.2019.02.004 [doi]
AB  - OBJECTIVE: To determine the sensitivity to change and minimal clinically 
      important difference (MCID) for the self-administered Locomotor Capabilities 
      Index-5 (LCI-5) in people with lower limb amputation undergoing prosthetic 
      training. DESIGN: Prospective single-group observational study. METHODS: The 
      LCI-5 was administered to 110 patients (69 males [63%]; median [interquartile 
      range] age, 60 [48-69] years) before and after prosthetic training. The external 
      anchor administered after the program was a 7-point Global Rating of Change Scale 
      (GRCS) designed to quantify the effect (improvement or deterioration) of the 
      intervention. RESULTS: Test-retest reliability of the LCI-5 (n=30) was high 
      (intraclass correlation coefficient [ICC(2,1)]=0.92). The minimum detectable 
      change at the 95% confidence level was 5.66 points. After triangulating these 
      results with those of the mean-change approach and receiver operating 
      characteristic (ROC) curve analysis (area under the ROC curve>/=0.90), based on a 
      different GRCS score splitting, we identified 2 cutoffs for the LCI-5: a change 
      of 7 points, indicating the MCID, and 12 points, indicating "large improvement" 
      in locomotor capabilities (12.5% and 21.4% of the maximum possible score, 
      respectively). CONCLUSIONS: The LCI-5 showed a high ability to detect change over 
      time (responsiveness). The 2 proposed values (MCID of 7 points and large 
      improvement of 12 points), based on a mix of distribution- and anchor-based 
      approaches, represent cutoffs that can accurately identify 2 different levels of 
      true change (as perceived by the patient) in locomotor capability after 
      prosthetic training.
CI  - Copyright (c) 2019 Elsevier Masson SAS. All rights reserved.
FAU - Franchignoni, Franco
AU  - Franchignoni F
AD  - ICS Maugeri, IRCCS, Pavia, Italy.
FAU - Traballesi, Marco
AU  - Traballesi M
AD  - Santa Lucia Foundation, IRCCS, Rome, Italy.
FAU - Monticone, Marco
AU  - Monticone M
AD  - Department of Medical Sciences and Public Health, University of Cagliari, 
      Cagliari, Italy; Neurorehabilitation Unit, Department of Neuroscience and 
      Rehabilitation, G. Brotzu Hospital, Cagliari, Italy.
FAU - Giordano, Andrea
AU  - Giordano A
AD  - ICS Maugeri, IRCCS, Pavia, Italy.
FAU - Brunelli, Stefano
AU  - Brunelli S
AD  - Santa Lucia Foundation, IRCCS, Rome, Italy.
FAU - Ferriero, Giorgio
AU  - Ferriero G
AD  - ICS Maugeri, IRCCS, Pavia, Italy. Electronic address: 
      giorgio.ferriero@icsmaugeri.it.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20190406
PL  - Netherlands
TA  - Ann Phys Rehabil Med
JT  - Annals of physical and rehabilitation medicine
JID - 101502773
SB  - IM
MH  - Aged
MH  - Amputation, Surgical/*rehabilitation
MH  - *Artificial Limbs
MH  - Female
MH  - Humans
MH  - Locomotion/*physiology
MH  - Lower Extremity/physiopathology/*surgery
MH  - Male
MH  - Middle Aged
MH  - *Minimal Clinically Important Difference
MH  - Prospective Studies
MH  - Reproducibility of Results
MH  - Surveys and Questionnaires/*standards
OTO - NOTNLM
OT  - Leg prosthesis
OT  - Lower-limb amputation
OT  - Outcome assessment
OT  - Prosthetic training
OT  - Psychometrics
OT  - Rehabilitation
EDAT- 2019/04/10 06:00
MHDA- 2019/12/18 06:00
CRDT- 2019/04/10 06:00
PHST- 2018/10/29 00:00 [received]
PHST- 2019/02/08 00:00 [revised]
PHST- 2019/02/23 00:00 [accepted]
PHST- 2019/04/10 06:00 [pubmed]
PHST- 2019/12/18 06:00 [medline]
PHST- 2019/04/10 06:00 [entrez]
AID - S1877-0657(19)30034-X [pii]
AID - 10.1016/j.rehab.2019.02.004 [doi]
PST - ppublish
SO  - Ann Phys Rehabil Med. 2019 May;62(3):137-141. doi: 10.1016/j.rehab.2019.02.004. 
      Epub 2019 Apr 6.