PMID- 30965902
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 9
IP  - 11
DP  - 2017 Nov 10
TI  - Novel Isocyanate-Modified Carrageenan Polymer Materials: Preparation, 
      Characterization and Application Adsorbent Materials of Pharmaceuticals.
LID - 10.3390/polym9110595 [doi]
LID - 595
AB  - The present study focused on the synthesis and application of novel 
      isocyanate-modified carrageenan polymers as sorbent materials for 
      pre-concentration and removal of diclofenac (DCF) and carbamazepine (CBZ) in 
      different aqueous matrices (surface waters and wastewaters). The polymer 
      materials were characterized using Fourier transform infrared spectroscopy 
      (FTIR), X-ray diffraction (XRD), Thermal Gravimetric Analysis (TGA) and Scanning 
      Electron Microscopy (SEM). The effects on the adsorption behavior were studied, 
      and the equilibrium data were fitted by the Langmuir and Freundlich models. The 
      maximum adsorption capacity (Q(max)) was determined by Langmuir(-)Freundlich model 
      and was ranged for iota-carrageenan (iCAR) from 7.44 to 8.51 mg/g for CBZ and 
      23.41 to 35.78 mg/g for DCF and for kappa-carrageenan (kCAR) from 7.07 to 13.78 
      mg/g for CBZ and 22.66 to 49.29 mg/g for DCF. In the next step, dispersive solid 
      phase extraction (D-SPE) methodology followed by liquid desorption and liquid 
      chromatography mass spectrometry (LC/MS) has been developed and validated. The 
      factors, which affect the performance of D-SPE, were investigated. Then, the 
      optimization of extraction time, sorbent mass and eluent's volume was carried out 
      using a central composite design (CCD) and response surface methodology (RSM). 
      Under the optimized conditions, good linear relationships have been achieved with 
      the correlation coefficient (R(2)) varying from 0.9901 to 0.995. The limits of 
      detections (LODs) and limits of quantifications (LOQs) ranged 0.042(-)0.090 mug/L 
      and 0.137(-)0.298 mug/L, respectively. The results of the recoveries were 70(-)108% 
      for both analytes, while the precisions were 2.8(-)17.5% were obtained, which 
      indicated that the method was suitable for the analysis of both compounds in 
      aqueous matrices.
FAU - Papageorgiou, Myrsini
AU  - Papageorgiou M
AUID- ORCID: 0000-0002-5284-2141
AD  - Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle 
      University of Thessaloniki, GR-541 24 Thessaloniki, Greece. 
      myrsinipapag@gmail.com.
FAU - Nanaki, Stavroula G
AU  - Nanaki SG
AD  - Laboratory of Polymer Chemistry and Technology, Department of Chemistry, 
      Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece. 
      sgnanaki@chem.auth.gr.
FAU - Kyzas, George Z
AU  - Kyzas GZ
AUID- ORCID: 0000-0003-1516-3761
AD  - Hephaestus Advanced Laboratory, Eastern Macedonia and Thrace Institute of 
      Technology, GR-654 04 Kavala, Greece. georgekyzas@gmail.com.
FAU - Koulouktsi, Christina
AU  - Koulouktsi C
AD  - Laboratory of Polymer Chemistry and Technology, Department of Chemistry, 
      Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece. 
      ckoulouktsi@pharmathen.com.
FAU - Bikiaris, Dimitrios N
AU  - Bikiaris DN
AUID- ORCID: 0000-0001-8458-4952
AD  - Laboratory of Polymer Chemistry and Technology, Department of Chemistry, 
      Aristotle University of Thessaloniki, GR-541 24 Thessaloniki, Greece. 
      dbic@chem.auth.gr.
FAU - Lambropoulou, Dimitra A
AU  - Lambropoulou DA
AD  - Laboratory of Environmental Pollution Control, Department of Chemistry, Aristotle 
      University of Thessaloniki, GR-541 24 Thessaloniki, Greece. dlambro@chem.auth.gr.
LA  - eng
PT  - Journal Article
DEP - 20171110
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC6418578
OTO - NOTNLM
OT  - carbamazepine
OT  - carrageenan polymers
OT  - diclofenac
OT  - dispersive solid phase extraction
OT  - response surface methodology
COIS- The authors declare no conflict of interest.
EDAT- 2017/11/10 00:00
MHDA- 2017/11/10 00:01
PMCR- 2017/11/10
CRDT- 2019/04/11 06:00
PHST- 2017/09/27 00:00 [received]
PHST- 2017/11/04 00:00 [revised]
PHST- 2017/11/06 00:00 [accepted]
PHST- 2019/04/11 06:00 [entrez]
PHST- 2017/11/10 00:00 [pubmed]
PHST- 2017/11/10 00:01 [medline]
PHST- 2017/11/10 00:00 [pmc-release]
AID - polym9110595 [pii]
AID - polymers-09-00595 [pii]
AID - 10.3390/polym9110595 [doi]
PST - epublish
SO  - Polymers (Basel). 2017 Nov 10;9(11):595. doi: 10.3390/polym9110595.