PMID- 30970709
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 9
IP  - 1
DP  - 2017 Jan 20
TI  - A Comprehensive Systematic Study on Thermoresponsive Gels: Beyond the Common 
      Architectures of Linear Terpolymers.
LID - 10.3390/polym9010031 [doi]
LID - 31
AB  - In this study, seven thermoresponsive methacrylate terpolymers with the same 
      molar mass (MM) and composition but various architectures were successfully 
      synthesized using group transfer polymerization (GTP). These terpolymers were 
      based on tri(ethylene glycol) methyl ether methacrylate (TEGMA, A unit), n-butyl 
      methacrylate (BuMA, B unit), and 2-(dimethylamino)ethyl methacrylate (DMAEMA, C 
      unit). Along with the more common ABC, ACB, BAC, and statistical architectures, 
      three diblock terpolymers were also synthesized and investigated for the first 
      time, namely (AB)C, A(BC), and B(AC); where the units in the brackets are 
      randomly copolymerized. Two BC diblock copolymers were also synthesized for 
      comparison. Their hydrodynamic diameters and their effective pK(a)s were 
      determined by dynamic light scattering (DLS) and hydrogen ion titrations, 
      respectively. The self-assembly behavior of the copolymers was also visualized by 
      transmission electron microscopy (TEM). Both dilute and concentrated aqueous 
      copolymer solutions were extensively studied by visual tests and their cloud 
      points (CP) and gel points were determined. It is proven that the aqueous 
      solution properties of the copolymers, with specific interest in their 
      thermoresponsive properties, are influenced by the architecture, with the ABC and 
      A(BC) ones to show clear sol-gel transition.
FAU - Constantinou, Anna P
AU  - Constantinou AP
AD  - Department of Materials, Imperial College London, Royal School of Mines, 
      Exhibition Road, London SW7 2AZ, UK. anna.constantinou14@imperial.ac.uk.
FAU - Zhao, Hanyi
AU  - Zhao H
AD  - Department of Materials, Imperial College London, Royal School of Mines, 
      Exhibition Road, London SW7 2AZ, UK. hanyi.zhao15@imperial.ac.uk.
FAU - McGilvery, Catriona M
AU  - McGilvery CM
AUID- ORCID: 0000-0002-4849-0251
AD  - Department of Materials, Imperial College London, Royal School of Mines, 
      Exhibition Road, London SW7 2AZ, UK. catriona.mcgilvery@imperial.ac.uk.
FAU - Porter, Alexandra E
AU  - Porter AE
AD  - Department of Materials, Imperial College London, Royal School of Mines, 
      Exhibition Road, London SW7 2AZ, UK. a.porter@imperial.ac.uk.
FAU - Georgiou, Theoni K
AU  - Georgiou TK
AUID- ORCID: 0000-0003-4474-6931
AD  - Department of Materials, Imperial College London, Royal School of Mines, 
      Exhibition Road, London SW7 2AZ, UK. t.georgiou@imperial.ac.uk.
LA  - eng
PT  - Journal Article
DEP - 20170120
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC6432086
OTO - NOTNLM
OT  - 2-(dimethylamino)ethyl methacrylate
OT  - 3-D printing
OT  - complex architectures
OT  - group transfer polymerization (GTP)
OT  - injectable gels
OT  - terpolymers
OT  - thermoresponsive polymers
OT  - well-defined polymers
COIS- The authors declare no conflict of interest.
EDAT- 2017/01/20 00:00
MHDA- 2017/01/20 00:01
PMCR- 2017/01/20
CRDT- 2019/04/12 06:00
PHST- 2016/12/04 00:00 [received]
PHST- 2017/01/12 00:00 [revised]
PHST- 2017/01/16 00:00 [accepted]
PHST- 2019/04/12 06:00 [entrez]
PHST- 2017/01/20 00:00 [pubmed]
PHST- 2017/01/20 00:01 [medline]
PHST- 2017/01/20 00:00 [pmc-release]
AID - polym9010031 [pii]
AID - polymers-09-00031 [pii]
AID - 10.3390/polym9010031 [doi]
PST - epublish
SO  - Polymers (Basel). 2017 Jan 20;9(1):31. doi: 10.3390/polym9010031.