PMID- 30975686 OWN - NLM STAT- MEDLINE DCOM- 20200508 LR - 20200508 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 9 IP - 4 DP - 2019 Apr 11 TI - Cost and cost-effectiveness of mHealth interventions for the prevention and control of type 2 diabetes mellitus: a protocol for a systematic review. PG - e027490 LID - 10.1136/bmjopen-2018-027490 [doi] LID - e027490 AB - INTRODUCTION: Type 2 diabetes mellitus (T2DM) remains one of the most common chronic diseases of adulthood which creates high degrees of morbidity and mortality worldwide. The incidence of T2DM continues to rise and recently, mHealth interventions have been increasingly used in the prevention, monitoring and management of T2DM. The aim of this study is to systematically review the published evidence on cost and cost-effectiveness of mHealth interventions for T2DM, as well as assess the quality of reporting of the evidence. METHODS AND ANALYSIS: A comprehensive review of PubMed, EMBASE, Science Direct and Web of Science of articles published until January 2019 will be conducted. Included studies will be partial or full economic evaluations which provide cost or cost-effectiveness results for mHealth interventions targeting individuals diagnosed with, or at risk of, T2DM. The quality of reporting evidence will be assessed using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS) checklist. Results will be presented using a flowchart following the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) guidelines. Graphical and tabulated representations of the results will be created for both descriptive and numerical results. The cost and cost-effectiveness values will be presented as reported by the original studies as well as converted into international dollars to allow comparability. As we are predicting heterogenous results, we will conduct a narrative and interpretive analysis of the data. ETHICS AND DISSEMINATION: No formal approval or review of ethics is required for this systematic review as it will involve the collection and analysis of secondary data. This protocol follows the current PRISMA-P guidelines. The review will provide information on the cost and cost-effectiveness of mHealth interventions targeting T2DM. These results will be disseminated through publication and submission to conferences for presentations and posters. PROSPERO REGISTRATION NUMBER: CRD42019123476. CI - (c) Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Rinaldi, Giulia AU - Rinaldi G AUID- ORCID: 0000-0002-4212-4584 AD - Medical Department, St George's University, London, Greater London, UK. FAU - Hijazi, Alexa AU - Hijazi A AD - Institute for Global Health, University College London, London, UK. FAU - Haghparast-Bidgoli, Hassan AU - Haghparast-Bidgoli H AUID- ORCID: 0000-0001-6365-2944 AD - Institute for Global Health, University College London, London, UK. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190411 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 SB - IM MH - Cost-Benefit Analysis MH - Diabetes Mellitus, Type 2/*prevention & control/*therapy MH - Humans MH - Research Design MH - Systematic Reviews as Topic MH - Telemedicine/*economics PMC - PMC6500237 OTO - NOTNLM OT - general diabetes OT - health economics OT - telemedicine COIS- Competing interests: None declared. EDAT- 2019/04/13 06:00 MHDA- 2020/05/10 06:00 PMCR- 2019/04/11 CRDT- 2019/04/13 06:00 PHST- 2019/04/13 06:00 [entrez] PHST- 2019/04/13 06:00 [pubmed] PHST- 2020/05/10 06:00 [medline] PHST- 2019/04/11 00:00 [pmc-release] AID - bmjopen-2018-027490 [pii] AID - 10.1136/bmjopen-2018-027490 [doi] PST - epublish SO - BMJ Open. 2019 Apr 11;9(4):e027490. doi: 10.1136/bmjopen-2018-027490.