PMID- 30982251
OWN - NLM
STAT- MEDLINE
DCOM- 20190429
LR  - 20190429
IS  - 0376-2491 (Print)
IS  - 0376-2491 (Linking)
VI  - 99
IP  - 14
DP  - 2019 Apr 9
TI  - [Long-term outcomes of multiple arterial off-pump coronary artery bypass 
      grafting].
PG  - 1053-1057
LID - 10.3760/cma.j.issn.0376-2491.2019.14.004 [doi]
AB  - Objective: To evaluate the long-term clinical outcomes of multiple arterial 
      off-pump coronary artery bypass grafting (OPCAB) on left main coronary artery or 
      multivessel disease. Methods: A total of 329 patients [303 males and 26 females, 
      with a mean age of (55.1+/-9.1) years old] with left main coronary artery or 
      multivessel disease who underwent isolated multiple arterial OPCAB in Ruijin 
      Hospital between January 2006 and June 2018 were included. The baseline 
      characteristics, perioperative and long-term outcomes were analyzed. Kaplan-Meier 
      analysis was applied for estimation of freedom from major adverse cardiac and 
      cerebrovascular events (MACCE) and overall survival. Independent predictors of 
      MACCE were assessed by Cox regression analysis. Results: The perioperative 
      mortality was only 0.9% (3/329). The median follow-up time was 65(22, 126) 
      months, and 302 (91.8%) patients were followed up. The long-term MACCE rate, 
      mortality, cardiac mortality, myocardial infarction (MI) rate, stroke rate and 
      target vessel revascularization (TVR) rate were 13.9%, 4.6%, 1.3%, 3.6%, 6.0% and 
      6.0%, respectively. Among the alive patients, 51.3% were in New York Heart 
      Association (NYHA) Ⅰ class and 80.9% had no recurrence of angina pectoris. The 
      estimated 5-year and 10-year overall survival rates were 97.3% and 93.1%, 
      respectively. The estimated 5-year and 10-year freedom from MACCE survival rates 
      were 91.5% and 78.0%, respectively. Senility (OR=1.058, 95%CI: 1.020-1.097, 
      P=0.002) and history of MI (OR=2.200, 95%CI: 1.131-4.412, P=0.021) were the 
      independent risk factors for late MACCE. Conclusion: Multiple arterial OPCAB 
      appears to be safe and with excellent clinical outcomes in treating left main 
      coronary artery or multivessel disease.
FAU - Sun, Y J
AU  - Sun YJ
AD  - Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University 
      School of Medicine, Shanghai 200025, China.
FAU - Qiu, J P
AU  - Qiu JP
FAU - Zhu, P X
AU  - Zhu PX
FAU - Zhou, Y Z
AU  - Zhou YZ
FAU - Chen, A Q
AU  - Chen AQ
FAU - Wang, Z
AU  - Wang Z
FAU - Zhou, M
AU  - Zhou M
FAU - Ye, X F
AU  - Ye XF
FAU - Liu, J
AU  - Liu J
FAU - Zhao, Q
AU  - Zhao Q
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Yi Xue Za Zhi
JT  - Zhonghua yi xue za zhi
JID - 7511141
SB  - IM
MH  - Coronary Artery Bypass
MH  - *Coronary Artery Bypass, Off-Pump
MH  - *Coronary Artery Disease
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - *Myocardial Infarction
MH  - Risk Factors
MH  - *Stroke
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Coronary artery bypass, off-pump
OT  - Coronary artery disease
OT  - Multiple arterial graft
OT  - Multivessel disease
EDAT- 2019/04/16 06:00
MHDA- 2019/04/30 06:00
CRDT- 2019/04/15 06:00
PHST- 2019/04/15 06:00 [entrez]
PHST- 2019/04/16 06:00 [pubmed]
PHST- 2019/04/30 06:00 [medline]
AID - 10.3760/cma.j.issn.0376-2491.2019.14.004 [doi]
PST - ppublish
SO  - Zhonghua Yi Xue Za Zhi. 2019 Apr 9;99(14):1053-1057. doi: 
      10.3760/cma.j.issn.0376-2491.2019.14.004.