PMID- 30982518
OWN - NLM
STAT- MEDLINE
DCOM- 20190627
LR  - 20190627
IS  - 1873-4324 (Electronic)
IS  - 0003-2670 (Linking)
VI  - 1064
DP  - 2019 Aug 8
TI  - A concept for studying the transformation reaction of hexachlorocyclohexanes in 
      food webs using multi-element compound-specific isotope analysis.
PG  - 56-64
LID - S0003-2670(19)30319-8 [pii]
LID - 10.1016/j.aca.2019.03.030 [doi]
AB  - An analytical concept using stable isotope fractionation for analyzing persistent 
      organic pollutants (POPs) in food webs was developed and tested. We have 
      evaluated methods for the extraction and clean-up of hexachlorocyclohexane 
      isomers (HCHs) as the model compounds of POPs from water, soil, plant, milk, fish 
      oil and pork liver in order to study the reactive transport processes of HCHs in 
      food webs using multi-element compound-specific isotope analysis (CSIA). The 
      extraction and clean-up methods were evaluated for recovery efficiency and 
      isotope effects. The precision and accuracy for carbon, hydrogen and chlorine 
      isotope analysis were within the analytical precision of +/-0.5 per thousand, +/-5 per thousand and +/-0.3 per thousand, 
      respectively. The method was applied for stable isotope analysis of HCHs in 
      possible food webs from soil to plants, and to animals. Isotope compositions of 
      HCHs in cow/buffalo milk and dung, wild animal livers and seal blubber were 
      obtained and compared to the sources of HCHs. The magnitude of isotope enrichment 
      demonstrated the potential of CSIA for analyzing reactive transport processes of 
      HCHs in the food web. The concept using multi-element stable isotope analysis can 
      be applied for source identification, characterization of degradation mechanisms, 
      and particularly contaminant accumulation in the food web, which demonstrates the 
      potential in new scientific areas for CSIA.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Wu, Langping
AU  - Wu L
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
FAU - Moses, Sonya
AU  - Moses S
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
FAU - Liu, Yaqing
AU  - Liu Y
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
FAU - Renpenning, Julian
AU  - Renpenning J
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
FAU - Richnow, Hans H
AU  - Richnow HH
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany. Electronic address: 
      hans.richnow@ufz.de.
LA  - eng
PT  - Journal Article
DEP - 20190318
PL  - Netherlands
TA  - Anal Chim Acta
JT  - Analytica chimica acta
JID - 0370534
RN  - 0 (Carbon Isotopes)
RN  - 0 (Chlorine-37)
RN  - 0 (Fish Oils)
RN  - 0 (Isotopes)
RN  - 4R7X1O2820 (Chlorine)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
SB  - IM
MH  - Animals
MH  - Carbon Isotopes
MH  - Cattle
MH  - Chlorine
MH  - Fish Oils/chemistry
MH  - *Food Chain
MH  - Hexachlorocyclohexane/*analysis
MH  - *Isotope Labeling
MH  - Isotopes
MH  - Liver/chemistry
MH  - Mice
MH  - Milk/chemistry
OTO - NOTNLM
OT  - Extraction
OT  - Food web
OT  - Hexachlorocyclohexane
OT  - Isotope fractionation
OT  - Reactive transport
EDAT- 2019/04/16 06:00
MHDA- 2019/06/30 06:00
CRDT- 2019/04/16 06:00
PHST- 2018/12/26 00:00 [received]
PHST- 2019/03/04 00:00 [revised]
PHST- 2019/03/15 00:00 [accepted]
PHST- 2019/04/16 06:00 [entrez]
PHST- 2019/04/16 06:00 [pubmed]
PHST- 2019/06/30 06:00 [medline]
AID - S0003-2670(19)30319-8 [pii]
AID - 10.1016/j.aca.2019.03.030 [doi]
PST - ppublish
SO  - Anal Chim Acta. 2019 Aug 8;1064:56-64. doi: 10.1016/j.aca.2019.03.030. Epub 2019 
      Mar 18.