PMID- 30983916
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 1541-7891 (Print)
IS  - 2374-8907 (Electronic)
IS  - 1541-7891 (Linking)
VI  - 30
IP  - 2
DP  - 2019 Apr
TI  - A 1-Month Physical Therapy-Based Outpatient Program for Adults Awaiting Lung 
      Transplantation: A Retrospective Analysis of Exercise Capacity, Symptoms, and 
      Quality of Life.
PG  - 61-69
LID - 10.1097/CPT.0000000000000087 [doi]
AB  - PURPOSE: Rehabilitation can improve health outcomes in candidates for lung 
      transplantation. The purpose of this study was to retrospectively evaluate the 
      effect of a one-month physical therapy (PT)-based outpatient program on exercise 
      capacity, symptoms, quality of life and examine predictors of functional outcome 
      changes in adults awaiting lung transplantation. METHODS: Participants (n=141) 
      completed a 23-session exercise and educational program over one month. Outcomes 
      included 6-minute walk distance (6MWD), San Diego Shortness of Breath 
      Questionnaire (SOBQ), Center for Epidemiological Studies-Depression Scale (CESD), 
      and Ferrans and Powers Quality of Life Index Pulmonary Version III (QOL). 
      RESULTS: Participants were older (median age 63) with restrictive (59%) or 
      obstructive (24%) disease. Moderate-to-large improvements in 6MWD were observed 
      (69 m, p < 0.001, d = 0.72), independent of demographics, symptoms, and QOL. 
      Lower initial 6MWD and lower oxygen utilization were associated with greater 6MWD 
      improvements, with largest gains occurring in initial 6MWD < 305 m. 
      Small-to-moderate improvements were observed on CESD (p < 0.001, d = 0.26) and in 
      overall QOL (p < 0.001, d = 0.27), with a non-significant improvement observed on 
      SOBQ (p = 0.248, d = 0.13). CONCLUSIONS: Completion of a one-month PT-based 
      outpatient rehabilitation program was associated with improved exercise capacity, 
      depressive symptoms and QOL.
FAU - Byrd, Rebecca
AU  - Byrd R
AD  - Duke University Health System, Department of Physical and Occupational Therapy.
FAU - Smith, Patrick
AU  - Smith P
AD  - Duke University School of Medicine, Department of Psychiatry and Behavioral 
      Sciences.
FAU - Mohamedaly, Omar
AU  - Mohamedaly O
AD  - Duke University School of Medicine, Department of Medicine.
FAU - Snyder, Laurie D
AU  - Snyder LD
AD  - Duke University School of Medicine, Department of Medicine.
FAU - Pastva, Amy M
AU  - Pastva AM
AD  - Duke University School of Medicine, Departments of Orthopaedic Surgery, Medicine, 
      Cell Biology.
LA  - eng
GR  - P30 AG028716/AG/NIA NIH HHS/United States
PT  - Journal Article
PL  - United States
TA  - Cardiopulm Phys Ther J
JT  - Cardiopulmonary physical therapy journal
JID - 101155626
PMC - PMC6456901
MID - NIHMS959309
OTO - NOTNLM
OT  - exercise
OT  - rehabilitation
OT  - six-minute walk distance
COIS- Conflict of Interest The authors have no relevant financial relationships with 
      industry to disclose.
EDAT- 2019/04/16 06:00
MHDA- 2019/04/16 06:01
PMCR- 2020/04/01
CRDT- 2019/04/16 06:00
PHST- 2019/04/16 06:00 [entrez]
PHST- 2019/04/16 06:00 [pubmed]
PHST- 2019/04/16 06:01 [medline]
PHST- 2020/04/01 00:00 [pmc-release]
AID - 10.1097/CPT.0000000000000087 [doi]
PST - ppublish
SO  - Cardiopulm Phys Ther J. 2019 Apr;30(2):61-69. doi: 10.1097/CPT.0000000000000087.