PMID- 30987926
OWN - NLM
STAT- MEDLINE
DCOM- 20200803
LR  - 20200803
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Linking)
VI  - 208
DP  - 2019 Jun
TI  - Validation of the Brief Negative Symptom Scale and its association with 
      functioning.
PG  - 97-104
LID - S0920-9964(19)30128-8 [pii]
LID - 10.1016/j.schres.2019.04.005 [doi]
AB  - INTRODUCTION: The Brief Negative Symptom Scale (BNSS) includes five domains of 
      negative symptoms suggested by the NIMH Consensus Development Conference 
      (anhedonia, asociality, avolition, blunted affect, and alogia), which could be 
      clustered into two factors - Motivation-Pleasure (MAP) and Emotional Expressivity 
      (EE). Our study aims to examine the psychometric properties of BNSS, and its 
      association with functioning. METHODS: 274 individuals with schizophrenia were 
      assessed on the BNSS, Positive and Negative Syndrome Scale (PANSS), Scale for the 
      Assessment of Negative Symptoms (SANS), Global Assessment of Functioning Scale 
      (GAF), Calgary Depression Scale for Schizophrenia (CDSS), and Simpson-Angus 
      Extrapyramidal Side Effects Scale (SAS). Internal consistency was examined using 
      Cronbach's alpha. Concurrent, discriminant, and construct validity were examined. 
      Factor structure of BNSS was explored using confirmatory factor analyses. 
      Association between GAF and BNSS was examined with GAF as the dependent variable 
      and BNSS Total, MAP and EE, and BNSS five domains as independent variables in 
      three multiple regression models after controlling for covariates. RESULTS: BNSS 
      showed good internal consistency (Cronbach's alpha = 0.880) and validity. The 
      five-factor model fit the data better than the two-factor model; a second-order 
      model was superior to both models. More severe symptoms on BNSS Total 
      (B = -0.438, p < .001), MAP (B = -0.876, p < .001), Avolition (B = -2.503, 
      p < .001) and Asociality (B = -0.950, p = .001) were associated with lower GAF. 
      CONCLUSION: Our results lend support to the use of BNSS in clinical practice and 
      in future research into negative symptoms. Composite scores could be computed 
      using either the five-factor or second-order models. Negative symptoms, 
      particularly MAP, avolition and asociality, were associated with functioning.
CI  - Copyright (c) 2019. Published by Elsevier B.V.
FAU - Ang, Mei San
AU  - Ang MS
AD  - Research Division, Institute of Mental Health, Singapore.
FAU - Rekhi, Gurpreet
AU  - Rekhi G
AD  - Research Division, Institute of Mental Health, Singapore.
FAU - Lee, Jimmy
AU  - Lee J
AD  - Research Division, Institute of Mental Health, Singapore; North Region & 
      Department of Psychosis, Institute of Mental Health, Singapore; Lee Kong Chian 
      School of Medicine, Nanyang Technological University, Singapore. Electronic 
      address: jimmy_lee@imh.com.sg.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Validation Study
DEP - 20190413
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Adult
MH  - Aged
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Psychiatric Status Rating Scales/*standards
MH  - Psychometrics/instrumentation/*standards
MH  - Schizophrenia/*diagnosis/*physiopathology
MH  - Young Adult
EDAT- 2019/04/17 06:00
MHDA- 2020/08/04 06:00
CRDT- 2019/04/17 06:00
PHST- 2018/11/21 00:00 [received]
PHST- 2019/03/21 00:00 [revised]
PHST- 2019/04/04 00:00 [accepted]
PHST- 2019/04/17 06:00 [pubmed]
PHST- 2020/08/04 06:00 [medline]
PHST- 2019/04/17 06:00 [entrez]
AID - S0920-9964(19)30128-8 [pii]
AID - 10.1016/j.schres.2019.04.005 [doi]
PST - ppublish
SO  - Schizophr Res. 2019 Jun;208:97-104. doi: 10.1016/j.schres.2019.04.005. Epub 2019 
      Apr 13.