PMID- 30990060 OWN - NLM STAT- MEDLINE DCOM- 20200724 LR - 20200724 IS - 1549-7852 (Electronic) IS - 1040-8398 (Linking) VI - 60 IP - 11 DP - 2020 TI - Combination of emerging technologies for the extraction of bioactive compounds. PG - 1826-1841 LID - 10.1080/10408398.2019.1602823 [doi] AB - With the growing consumer demands for greener alternatives that do not involve toxic chemicals as well as the industry concerns of sustainable, nontoxic routes of extraction, the applications of novel extraction technologies in the food industry have been widely studied. This review discussed the novel extraction technologies including their mechanisms, protocols, influencing factors, advantages and drawbacks, as well as a comprehensive summary of the combination of the novel extraction technologies for phyto-bioactive compounds. Novel extraction methods, including ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE) and enzyme-assisted extraction (EAE), are considered as clean, green and efficient alternative to conventional extraction technologies. Their combinations, ultrasound-assisted enzymatic extraction (UAEE), microwave-assisted enzymatic extraction (MAEE) and ultrasonic microwave-assisted extraction (UMAE), can exhibit higher potential extraction ability. However, some of them need specific equipment. The food industry in the extraction sector should choose a proper extraction method which has a balance between product quality, process efficiency, production costs and environmentally friendly processes. The current review presented comprehensive references for future research on the novel extraction of phyto-bioactive compounds extraction.HighlightsNovel clean, green and efficient alternative to conventional extraction technologies are discussed.Combination of the novel extraction technologies for synergistic effects.Minimal degradation and enhanced extraction yields.Extraction mechanisms, advantages and drawbacks associated with novel extraction technologies. FAU - Wen, Le AU - Wen L AD - Department of Food Chemistry and Technology, Teagasc Food Research Centre, Ashtown, Dublin, Ireland. AD - Food Refrigeration and Computerized Food Technology (FRCFT), School of Biosystems and Food Engineering, Agriculture & Food Science Centre, University College Dublin (UCD), National University of Ireland, Belfield, Dublin, Ireland. FAU - Zhang, Zhihang AU - Zhang Z AD - Department of Food Chemistry and Technology, Teagasc Food Research Centre, Ashtown, Dublin, Ireland. FAU - Sun, Da-Wen AU - Sun DW AD - Food Refrigeration and Computerized Food Technology (FRCFT), School of Biosystems and Food Engineering, Agriculture & Food Science Centre, University College Dublin (UCD), National University of Ireland, Belfield, Dublin, Ireland. FAU - Sivagnanam, Saravana Periaswamy AU - Sivagnanam SP AD - Department of Food Chemistry and Technology, Teagasc Food Research Centre, Ashtown, Dublin, Ireland. FAU - Tiwari, Brijesh K AU - Tiwari BK AD - Department of Food Chemistry and Technology, Teagasc Food Research Centre, Ashtown, Dublin, Ireland. LA - eng PT - Journal Article PT - Review DEP - 20190416 PL - United States TA - Crit Rev Food Sci Nutr JT - Critical reviews in food science and nutrition JID - 8914818 SB - IM MH - Food Analysis/*methods MH - Food Industry/*trends MH - *Microwaves MH - *Ultrasonics OTO - NOTNLM OT - Novel extraction methods OT - combined extraction methods OT - enzyme-assisted extraction (EAE) OT - microwave-assisted extraction (MAE) OT - phyto-bioactive compounds OT - ultrasound-assisted extraction (UAE) EDAT- 2019/04/17 06:00 MHDA- 2020/07/25 06:00 CRDT- 2019/04/17 06:00 PHST- 2019/04/17 06:00 [pubmed] PHST- 2020/07/25 06:00 [medline] PHST- 2019/04/17 06:00 [entrez] AID - 10.1080/10408398.2019.1602823 [doi] PST - ppublish SO - Crit Rev Food Sci Nutr. 2020;60(11):1826-1841. doi: 10.1080/10408398.2019.1602823. Epub 2019 Apr 16.