PMID- 31002331
OWN - NLM
STAT- MEDLINE
DCOM- 20200330
LR  - 20200330
IS  - 1876-4479 (Electronic)
IS  - 1873-9946 (Print)
IS  - 1873-9946 (Linking)
VI  - 13
IP  - 11
DP  - 2019 Oct 28
TI  - Systematic Review: Components of a Comprehensive Geriatric Assessment in 
      Inflammatory Bowel Disease-A Potentially Promising but Often Neglected Risk 
      Stratification.
PG  - 1418-1432
LID - 10.1093/ecco-jcc/jjz082 [doi]
AB  - BACKGROUND: The population of older patients with inflammatory bowel disease 
      [IBD] is increasing. Patient age does not fully account for poor outcomes and its 
      clinical utility for risk stratification is limited. Comprehensive geriatric 
      assessment [CGA], comprising a somatic, functional, mental, and social assessment 
      or frailty, could be a predictor tool. AIMS: To systematically review literature 
      on the kind of components of a CGA being used in adult IBD patients and the 
      association of these components with adverse health outcomes. METHODS: An 
      electronic literature search was performed on January 16, 2018, using PubMed, 
      Embase, Web of Science, the Cochrane Library, CENTRAL, Emcare, and PsycINFO. 
      Longitudinal studies relating somatic, functional, mental, and social assessment 
      or frailty to adverse health outcomes during follow-up in IBD patients were 
      included. The Newcastle-Ottawa scale was used to assess individual study quality. 
      RESULTS: Of 4080 identified citations, 27 studies were included, reporting 169 
      associations. Median sample size was 108 patients (interquartile range [IQR] 
      60-704). No studies performed subgroup analyses on older patients, and the 
      highest mean age reported was 52.7 years. Somatic and functional assessments were 
      used in three studies, mental in 24, and social in five. No study assessed 
      cognitive status, functional performance, or frailty. In 62 associations [36.7%], 
      components of a CGA were significantly associated with adverse health outcome 
      measurements. CONCLUSIONS: Components of a CGA were associated with adverse 
      health outcomes in IBD patients, but older patients were under-represented. More 
      studies among older patients with IBD are warranted to further establish the 
      clinical impact of a CGA.
CI  - Copyright (c) European Crohn's and Colitis Organisation (ECCO) 2019.
FAU - Asscher, Vera E R
AU  - Asscher VER
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - Lee-Kong, Felicia V Y
AU  - Lee-Kong FVY
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - Kort, Esther D
AU  - Kort ED
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - van Deudekom, Floor J
AU  - van Deudekom FJ
AD  - Department of Gerontology and Geriatrics, Leiden University Medical Center, 
      Leiden, The Netherlands.
FAU - Mooijaart, Simon P
AU  - Mooijaart SP
AD  - Department of Gerontology and Geriatrics, Leiden University Medical Center, 
      Leiden, The Netherlands.
AD  - Institute for Evidence-Based Medicine in Old Age [IEMO], Leiden, The Netherlands.
FAU - Maljaars, P W Jeroen
AU  - Maljaars PWJ
AD  - Department of Gastroenterology and Hepatology, Leiden University Medical Center, 
      Leiden, The Netherlands.
LA  - eng
PT  - Journal Article
PT  - Systematic Review
PL  - England
TA  - J Crohns Colitis
JT  - Journal of Crohn's & colitis
JID - 101318676
SB  - IM
MH  - Aged
MH  - Anxiety/diagnosis
MH  - Depression/diagnosis
MH  - Disease Progression
MH  - *Geriatric Assessment
MH  - Hospitalization
MH  - Humans
MH  - Inflammatory Bowel Diseases/*complications/psychology
MH  - Quality of Life
MH  - Risk Assessment
MH  - Social Isolation
PMC - PMC6821240
OTO - NOTNLM
OT  - Crohn's disease
OT  - comprehensive geriatric assessment
OT  - ulcerative colitis
EDAT- 2019/04/20 06:00
MHDA- 2020/03/31 06:00
PMCR- 2019/04/19
CRDT- 2019/04/20 06:00
PHST- 2019/04/20 06:00 [pubmed]
PHST- 2020/03/31 06:00 [medline]
PHST- 2019/04/20 06:00 [entrez]
PHST- 2019/04/19 00:00 [pmc-release]
AID - 5475282 [pii]
AID - jjz082 [pii]
AID - 10.1093/ecco-jcc/jjz082 [doi]
PST - ppublish
SO  - J Crohns Colitis. 2019 Oct 28;13(11):1418-1432. doi: 10.1093/ecco-jcc/jjz082.