PMID- 31006022 OWN - NLM STAT- MEDLINE DCOM- 20200203 LR - 20200203 IS - 1569-9285 (Electronic) IS - 1569-9285 (Linking) VI - 29 IP - 3 DP - 2019 Sep 1 TI - Does the site of coronary endarterectomy have an impact on the clinical outcomes and graft patency? PG - 402-408 LID - 10.1093/icvts/ivz099 [doi] AB - OBJECTIVES: To explore whether coronary endarterectomy (CE) sites have obvious impacts on the clinical outcomes and graft patency in off-pump coronary artery bypass (OPCAB). METHODS: The patients who underwent OPCAB with CE in our unit between January 2009 and December 2016 were included. The patients and the grafts were grouped according to the CE sites. The primary end points were mid-term main adverse cardiovascular and cerebrovascular events. RESULTS: In total, 290 patients who underwent OPCAB with CE were included. CE of the left anterior descending artery (LAD), left circumflex artery and the right coronary artery was performed in 46, 30 and 194 patients, respectively. There were 60, 42 and 217 grafts anastomosed to LAD-CE, left circumflex artery-CE and right coronary artery-CE sites in 290 patients. CE was not performed in the 20 patients requiring multivessel CE. There was no significant difference in perioperative outcomes. The average follow-up time was 51 months (12-103 months). There was no significant difference in mid-term death, main adverse cardiovascular and cerebrovascular events, myocardial infarction (MI), stroke, Canadian Cardiovascular Classification for angina class and 1-year graft patency among the 3 groups. However, the rate of New York Heart Association (NYHA) class III or IV (LAD vs left circumflex artery: 59% vs 25%, P = 0.011; LAD vs right coronary artery: 59% vs 27%, P < 0.001) was higher in the LAD group than in the other groups. These results were consistent with the Kaplan-Meier curves of freedom from the adverse events. CONCLUSIONS: CE sites had no obvious impact on mid-term death, main adverse cardiovascular and cerebrovascular events, MI, stroke, Canadian Cardiovascular Classification for angina class and 1-year graft patency in patients who underwent OPCAB with CE. The patients undergoing LAD-CE had higher rates of NYHA class III or IV. CI - (c) The Author(s) 2019. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved. FAU - Zhu, Pengxiong AU - Zhu P AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Ye, Xiaofeng AU - Ye X AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Chen, Anqing AU - Chen A AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Liu, Jun AU - Liu J AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Wang, Zhe AU - Wang Z AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Zhou, Mi AU - Zhou M AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. FAU - Zhao, Qiang AU - Zhao Q AD - Department of Cardiac Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. LA - eng PT - Journal Article PL - England TA - Interact Cardiovasc Thorac Surg JT - Interactive cardiovascular and thoracic surgery JID - 101158399 SB - IM MH - Aged MH - *Blood Vessel Prosthesis MH - Coronary Angiography MH - Coronary Artery Bypass, Off-Pump/*methods MH - Coronary Artery Disease/diagnosis/*surgery MH - Coronary Vessels/diagnostic imaging/physiopathology/*surgery MH - Endarterectomy/*methods MH - Female MH - Humans MH - Male MH - Middle Aged MH - Treatment Outcome MH - Vascular Patency/*physiology OTO - NOTNLM OT - Coronary artery disease OT - Endarterectomy OT - Graft patency OT - Off-pump coronary bypass grafting EDAT- 2019/04/22 06:00 MHDA- 2020/02/06 06:00 CRDT- 2019/04/22 06:00 PHST- 2018/10/25 00:00 [received] PHST- 2019/03/13 00:00 [revised] PHST- 2019/03/17 00:00 [accepted] PHST- 2019/04/22 06:00 [pubmed] PHST- 2020/02/06 06:00 [medline] PHST- 2019/04/22 06:00 [entrez] AID - 5475798 [pii] AID - 10.1093/icvts/ivz099 [doi] PST - ppublish SO - Interact Cardiovasc Thorac Surg. 2019 Sep 1;29(3):402-408. doi: 10.1093/icvts/ivz099.