PMID- 31011350 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1735-0328 (Print) IS - 1726-6890 (Electronic) IS - 1726-6882 (Linking) VI - 17 IP - Suppl2 DP - 2018 TI - Evaluation of Antimicrobial Properties of Conventional Poly(Methyl Methacrylate) Denture Base Resin Materials Containing Hydrothermally Synthesised Anatase TiO(2) Nanotubes against Cariogenic Bacteria and Candida albicans. PG - 161-172 AB - The purpose of this study was to investigate the antimicrobial properties of a conventional poly methyl methacrylate (PMMA) modified with hydrothermally synthesised titanium dioxide nanotubes (TNTs). Minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and minimum fungicidal concentrations (MFC) for planktonic cells of the TiO(2) nanotubes solution against Lactobacillus acidophilus, Streptococcus mutans and Candida albicans were determined. The powder of conventional acrylic resin was modified using 2.5% and 5% by weight synthesised titanium dioxide (TiO(2)) nanotubes, and rectangular-shaped specimens (10 mm x 10 mm x 3 mm) were fabricated. The antimicrobial properties of ultraviolet (UV) and non-UV irradiated modified, and non-modified acrylic resins were evaluated using the estimation of planktonic cell count and biofilm formation of the three microorganisms mentioned above. The data were analysed by one-way analysis of variance (ANOVA), followed by a post-hoc Tukey's test at a significance level of 5%. MIC, for Streptococcus. mutans, Lactobacillus. acidophilus, and Candida. albicans, MBC for S. mutans and L. acidophilus and MFC for Candida. albicans were obtained more than 2100 microg/mL. The results of this study indicated a significant reduction in both planktonic cell count and biofilm formation of modified UV-activated acrylic specimens compared with the control group (p = 0.00). According to the results of the current study, it can be concluded that PMMA/TiO(2) nanotube composite can be considered as a promising new material for antimicrobial approaches. FAU - Abdulrazzaq Naji, Sahar AU - Abdulrazzaq Naji S AD - Foundation of Technical Education, College of Health and Medical Technology, Baghdad, Iraq. AD - Department of Dental Biomaterials, School of Dentistry, International Campus, Tehran University of Medical Sciences (IC-TUMS), Tehran, Iran. FAU - Jafarzadeh Kashi, Tahereh Sadat AU - Jafarzadeh Kashi TS AD - Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. AD - Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran. FAU - Pourhajibagher, Maryam AU - Pourhajibagher M AD - Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran. AD - Dental Implant Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran. AD - Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. FAU - Behroozibakhsh, Marjan AU - Behroozibakhsh M AD - Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. AD - Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran. FAU - Masaeli, Reza AU - Masaeli R AD - Department of Dental Biomaterials, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran. AD - Research Center for Science and Technology in Medicine, Tehran University of Medical Sciences, Tehran, Iran. FAU - Bahador, Abbas AU - Bahador A AD - Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran. AD - Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran. LA - eng PT - Journal Article PL - Netherlands TA - Iran J Pharm Res JT - Iranian journal of pharmaceutical research : IJPR JID - 101208407 PMC - PMC6447881 OTO - NOTNLM OT - Antimicrobial properties OT - Biofilm OT - Candida albicans OT - Cariogenic bacteria OT - Denture base resin OT - Titania nanotubes EDAT- 2018/01/01 00:00 MHDA- 2018/01/01 00:01 PMCR- 2018/01/01 CRDT- 2019/04/24 06:00 PHST- 2019/04/24 06:00 [entrez] PHST- 2018/01/01 00:00 [pubmed] PHST- 2018/01/01 00:01 [medline] PHST- 2018/01/01 00:00 [pmc-release] AID - ijpr-17-161 [pii] PST - ppublish SO - Iran J Pharm Res. 2018;17(Suppl2):161-172.