PMID- 31013497
OWN - NLM
STAT- MEDLINE
DCOM- 20200210
LR  - 20200210
IS  - 1423-0259 (Electronic)
IS  - 0030-3747 (Linking)
VI  - 63
IP  - 1
DP  - 2020
TI  - The Role of Disorganization of Retinal Inner Layers as Predictive Factor of 
      Postoperative Outcome in Patients with Epiretinal Membrane.
PG  - 13-17
LID - 10.1159/000499370 [doi]
AB  - PURPOSE: The purpose of this retrospective study was to evaluate the 
      disorganization of the retinal inner layers (DRIL) as a potential predictive 
      factor of postoperative visual outcome in patients with idiopathic epiretinal 
      membrane (iERM), treated with pars plana vitrectomy (PPV). METHODS: Participants 
      in the study were 46 consecutive patients diagnosed with iERM, who underwent PPV. 
      Best corrected visual acuity (BCVA) measurement and spectral-domain optical 
      coherence tomography (SD-OCT) were performed at baseline (preoperatively), and at 
      months 3 and 6 postoperatively. DRIL and additional OCT parameters were assessed 
      at 1-mm-wide foveal centered area. RESULTS: DRIL was observed in 47.8% of 
      patients at baseline. There was statistically significant improvement in BCVA and 
      central retinal thickness (CRT) between baseline and months 6 and 12 in all 
      patients. There was a statistically significant difference in BCVA and CRT change 
      between patients with and without DRIL at months 6 and 12 compared to baseline, 
      showing that there was a correlation between change in BCVA or CRT and baseline 
      DRIL. Ellipsoid zone and external limiting membrane were intact in 91.3 and 
      95.7%, respectively, not affecting our results. CONCLUSIONS: Baseline DRIL has 
      been shown to be predictive of postoperative visual outcome in patients with 
      iERM, treated with PPV.
CI  - (c) 2019 S. Karger AG, Basel.
FAU - Garnavou-Xirou, Christina
AU  - Garnavou-Xirou C
AD  - Red Cross Hospital, Athens, Greece.
FAU - Xirou, Tina
AU  - Xirou T
AD  - Red Cross Hospital, Athens, Greece.
FAU - Gkizis, Ilias
AU  - Gkizis I
AD  - Red Cross Hospital, Athens, Greece.
FAU - Kabanarou, Stamatina A
AU  - Kabanarou SA
AD  - Red Cross Hospital, Athens, Greece.
FAU - Dimitriou, Eleni
AU  - Dimitriou E
AD  - 2nd Department of Ophthalmology, University of Athens, Athens, Greece.
FAU - Theodossiadis, Panagiotis
AU  - Theodossiadis P
AD  - 2nd Department of Ophthalmology, University of Athens, Athens, Greece.
FAU - Chatziralli, Irini
AU  - Chatziralli I
AD  - 2nd Department of Ophthalmology, University of Athens, Athens, Greece, 
      eirchat@yahoo.gr.
LA  - eng
PT  - Journal Article
DEP - 20190423
PL  - Switzerland
TA  - Ophthalmic Res
JT  - Ophthalmic research
JID - 0267442
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - *Epiretinal Membrane/pathology/surgery
MH  - Female
MH  - Fluorescein Angiography
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Predictive Value of Tests
MH  - Retina/*pathology
MH  - Retrospective Studies
MH  - Tomography, Optical Coherence
MH  - *Vitrectomy
OTO - NOTNLM
OT  - Disorganization of retinal inner layers
OT  - Epiretinal membrane
OT  - Optical coherence tomography
OT  - Vitrectomy
EDAT- 2019/04/24 06:00
MHDA- 2020/02/11 06:00
CRDT- 2019/04/24 06:00
PHST- 2018/12/31 00:00 [received]
PHST- 2019/02/26 00:00 [accepted]
PHST- 2019/04/24 06:00 [pubmed]
PHST- 2020/02/11 06:00 [medline]
PHST- 2019/04/24 06:00 [entrez]
AID - 000499370 [pii]
AID - 10.1159/000499370 [doi]
PST - ppublish
SO  - Ophthalmic Res. 2020;63(1):13-17. doi: 10.1159/000499370. Epub 2019 Apr 23.