PMID- 31020126
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 2514-2119 (Electronic)
IS  - 2514-2119 (Linking)
VI  - 2
IP  - 2
DP  - 2018 Jun
TI  - Endocardial linear infarct exclusion technique for non-ischaemic functional 
      mitral regurgitation caused by cardiac sarcoidosis: a case report.
PG  - yty046
LID - 10.1093/ehjcr/yty046 [doi]
LID - yty046
AB  - INTRODUCTION: Damage to the posterior wall of the left ventricle (LV) can cause 
      tethering mitral regurgitation (MR). We present a patient with non-ischaemic 
      tethering MR and congestive heart failure due to cardiac sarcoidosis who was 
      treated using an endocardial linear infarct exclusion technique. CASE 
      PRESENTATION: A 63-year-old woman with a history of uveitis presented to our 
      hospital complaining of dyspnoea. Echocardiography revealed dyskinesis of the 
      posterolateral wall of the LV and severe tethering MR (regurgitation volume: 
      92 mL). The LV ejection fraction was reduced to 45%. Cardiac catheterization 
      revealed no stenosis. Magnetic resonance imaging with late gadolinium enhancement 
      revealed a contrast effect and thinning of the posteriolateral wall. The abnormal 
      accumulation was also observed with fluorodeoxyglucose-positron emission 
      tomography. Together, these findings indicated cardiac sarcoidosis, and we 
      determined that cardiac sarcoidosis had resulted in aneurysm development in the 
      posterior wall of the LV, subsequent advanced tethering at the posterior mitral 
      valve cusp, and severe functional MR. The patient underwent an endocardial linear 
      infarct exclusion technique (ELIET), mitral annuloplasty, tricuspid annuloplasty, 
      and the full MAZE procedure. Histopathological analysis of the posterior wall 
      myocardium revealed marked thinning of the endocardium, replacement fibrosis, 
      lymphocyte infiltration, and epithelialization. These findings were consistent 
      with sarcoidosis. The patient's condition improved to New York Heart Association 
      (NYHA) Class I, and cardiac events were rare at 6 months after surgery. 
      DISCUSSION: Endocardial linear infarct exclusion technique is useful for treating 
      tethering MR. To our knowledge, this is the first reported case of successful 
      treatment using ELIET for non-ischaemic tethering MR caused by cardiac 
      sarcoidosis.
FAU - Matsuzaki, Yuichi
AU  - Matsuzaki Y
AD  - Department of Cardiovascular Surgery, Kyoto Daini Red Cross Hospital, 355-5 
      Haruobi-cho, Marutamachi Agaru, Kamanza-st, Nakagyo-ku, Kyoto, Japan.
FAU - Yamasaki, Takuma
AU  - Yamasaki T
AD  - Department of Cardiovascular Surgery, Kyoto Daini Red Cross Hospital, 355-5 
      Haruobi-cho, Marutamachi Agaru, Kamanza-st, Nakagyo-ku, Kyoto, Japan.
FAU - Hohri, Yu
AU  - Hohri Y
AD  - Department of Cardiovascular Surgery, Kyoto Daini Red Cross Hospital, 355-5 
      Haruobi-cho, Marutamachi Agaru, Kamanza-st, Nakagyo-ku, Kyoto, Japan.
FAU - Hiramatsu, Takeshi
AU  - Hiramatsu T
AD  - Department of Cardiovascular Surgery, Kyoto Daini Red Cross Hospital, 355-5 
      Haruobi-cho, Marutamachi Agaru, Kamanza-st, Nakagyo-ku, Kyoto, Japan.
LA  - eng
PT  - Case Reports
DEP - 20180418
PL  - England
TA  - Eur Heart J Case Rep
JT  - European heart journal. Case reports
JID - 101730741
PMC - PMC6176962
OTO - NOTNLM
OT  - Cardiac sarcoidosis
OT  - Case report
OT  - Mitral regurgitation
OT  - Non-ischaemic functional mitral regurgitation
EDAT- 2019/04/26 06:00
MHDA- 2019/04/26 06:01
PMCR- 2018/04/18
CRDT- 2019/04/26 06:00
PHST- 2018/01/09 00:00 [received]
PHST- 2018/03/21 00:00 [accepted]
PHST- 2019/04/26 06:00 [entrez]
PHST- 2019/04/26 06:00 [pubmed]
PHST- 2019/04/26 06:01 [medline]
PHST- 2018/04/18 00:00 [pmc-release]
AID - yty046 [pii]
AID - 10.1093/ehjcr/yty046 [doi]
PST - epublish
SO  - Eur Heart J Case Rep. 2018 Apr 18;2(2):yty046. doi: 10.1093/ehjcr/yty046. 
      eCollection 2018 Jun.