PMID- 31024822
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20201001
IS  - 2222-3959 (Print)
IS  - 2227-4898 (Electronic)
IS  - 2222-3959 (Linking)
VI  - 12
IP  - 4
DP  - 2019
TI  - Paired eye-control study of unilateral opaque bubble layer in femtosecond laser 
      assisted laser in situ keratomileusis.
PG  - 654-659
LID - 10.18240/ijo.2019.04.21 [doi]
AB  - AIM: To investigate the predictive factors of the opaque bubble layer (OBL) 
      compared to the fellow eye of same patients in FS200 femtosecond laser assisted 
      laser in situ keratomileusis (FS-LASIK). METHODS: This study consisted of 60 
      consecutive patients (120 eyes) with unilateral OBL during FS-LASIK. Eyes were 
      divided into OBL (the OBL eyes) and OBL-free groups (the fellow eyes) based on 
      the occurrence of OBL. The preoperative demographic data, refraction, 
      keratometry, corneal astigmatism, pachymetry, intraocular pressure and 
      intraoperative data including the outlet location of gas diffusing canal were 
      collected. Conditional logistic regression analysis was performed to find the 
      associated factors with OBL in the two groups by determining odds ratios (OR) and 
      95%CI. RESULTS: The preoperative demographic data, mean spherical errors, mean K 
      value, suction time, intraocular pressure and central cornea thickness were not 
      significantly different between the two groups. The outlet location of gas 
      diffusing canal (P<0.01, OR 7.16, 95%CI 2.53-20.32) and the corneal astigmatism 
      (P=0.013, OR 0.13, 95%CI 0.03-0.65) were significantly associated with the 
      incidence of OBL by multivariate logistic regression analysis. Visual acuity, 
      efficacy, and safety were comparable between the two groups two months after 
      surgery except for a slightly lower predictability value for the hard OBL eyes. 
      CONCLUSION: The reduction of the incidence of OBL is obvious when the outlet of 
      gas diffusing canal located at the posterior border of the corneoscleral limbus. 
      This is probably consequent to more effectiveness of gas diffusing canal. Corneal 
      astigmatism is also an independent protective factor for OBL formation.
FAU - Wei, Cheng-Hua
AU  - Wei CH
AD  - Department of Ophthalmology, the Second Affiliated Hospital of Soochow 
      University, Suzhou 215004, Jiangsu Province, China.
AD  - Department of Ophthalmology, the First Affiliated Hospital of Wannan Medical 
      College, Wuhu 241000, Anhui Province, China.
FAU - Dai, Qiao-Yun
AU  - Dai QY
AD  - Department of Ophthalmology, the First Affiliated Hospital of Wannan Medical 
      College, Wuhu 241000, Anhui Province, China.
FAU - Mei, Li-Xin
AU  - Mei LX
AD  - Department of Ophthalmology, the First Affiliated Hospital of Wannan Medical 
      College, Wuhu 241000, Anhui Province, China.
FAU - Ge, Yao
AU  - Ge Y
AD  - Department of Ophthalmology, the First Affiliated Hospital of Wannan Medical 
      College, Wuhu 241000, Anhui Province, China.
FAU - Zhang, Peng-Fei
AU  - Zhang PF
AD  - Department of Ophthalmology, the First Affiliated Hospital of Wannan Medical 
      College, Wuhu 241000, Anhui Province, China.
FAU - Song, E
AU  - Song E
AD  - Department of Ophthalmology, Lixiang Eye Hospital of Soochow University, Suzhou 
      215021, Jiangsu Province, China.
LA  - eng
PT  - Journal Article
DEP - 20190418
PL  - China
TA  - Int J Ophthalmol
JT  - International journal of ophthalmology
JID - 101553860
PMC - PMC6469571
OTO - NOTNLM
OT  - LASIK
OT  - femtosecond laser
OT  - location of gas diffusing canal
OT  - opaque bubble layer
EDAT- 2019/04/27 06:00
MHDA- 2019/04/27 06:01
PMCR- 2019/04/18
CRDT- 2019/04/27 06:00
PHST- 2018/09/05 00:00 [received]
PHST- 2018/10/19 00:00 [accepted]
PHST- 2019/04/27 06:00 [entrez]
PHST- 2019/04/27 06:00 [pubmed]
PHST- 2019/04/27 06:01 [medline]
PHST- 2019/04/18 00:00 [pmc-release]
AID - ijo-12-04-654 [pii]
AID - 10.18240/ijo.2019.04.21 [doi]
PST - epublish
SO  - Int J Ophthalmol. 2019 Apr 18;12(4):654-659. doi: 10.18240/ijo.2019.04.21. 
      eCollection 2019.