PMID- 31027050
OWN - NLM
STAT- MEDLINE
DCOM- 20190528
LR  - 20221005
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 98
IP  - 17
DP  - 2019 Apr
TI  - Experience of the management of coronary artery bypass graft only on moderate 
      ischemic mitral regurgitation: A single-center retrospective study.
PG  - e14969
LID - 10.1097/MD.0000000000014969 [doi]
LID - e14969
AB  - To summary the impact of off-pump coronary artery bypass grafting (CABG) only on 
      patients with moderate ischemic mitral regurgitation and survival.We 
      retrospectively analyzed 109 patients with coronary artery disease (CAD) 
      complicated by moderate mitral regurgitation, from January, 2008 to December, 
      2014, in the Department of Cardiovascular Surgery at the No. 2 Hospital of Jilin 
      University undergoing off pump CABG only. Preoperative clinical characteristics, 
      complications after surgery, and outcome (survivor or death) were assessed. We 
      observed the degree of mitral valve regurgitation, left ventricular ejection 
      fraction (LVEF), left ventricular and left atrial size, left ventricular 
      end-diastolic volume (LVEDV) preoperative, and New York Heart Association (NYHA) 
      functional class, postoperative 10 days before discharge, and 6 months and longer 
      after surgery. The statistical data were processed by SPSS 19 software with 
      computer; statistical significant difference with P < .05.Overall in-hospital 
      mortality was 2.75% (3 patients). Patients had lower mean LVEF in the 
      postoperative compared with the preoperative period, but all the patients had 
      higher LVEF since 6 months than preoperative period (P < .001). Compared with the 
      preoperative dates, postoperative valvular regurgitation, left ventricular and 
      atrial size and LVEDV postoperative 10 days before discharge, 6 months and more 
      longer after surgery reduced significantly (P < .001). Rapid atrial fibrillation 
      occurred in 19 cases during perioperative and returned to normal before 
      discharge. The symptom of angina was disappeared in all patients before 
      discharge. The mean follow-up time was 60.16 +/- 17.98 months (range 36-96 months). 
      Two patients died of major adverse cardiac events including heart failure and 
      ventricular fibrillation. Three patients died of lung cancer, and 2 patients died 
      of stroke during the longer follow-up.Off-pump CABG can be performed safely in 
      patients with CAD complicated by moderate mitral regurgitation. The efficacy of 
      CABG only is well demonstrated by the significant improvement of LVEF and NYHA 
      functional class, and by the decrease of left ventricular and atrial size, LVEDV, 
      and mitral regurgitation grade.
FAU - Wang, Weitie
AU  - Wang W
AD  - Department of Cardiovascular Surgery, the second Hospital of Jilin University, 
      Changchun, Jilin, China.
FAU - Li, Bo
AU  - Li B
FAU - Wang, Yong
AU  - Wang Y
FAU - Piao, Hulin
AU  - Piao H
FAU - Zhu, Zhicheng
AU  - Zhu Z
FAU - Xu, Rihao
AU  - Xu R
FAU - Li, Dan
AU  - Li D
FAU - Liu, Kexiang
AU  - Liu K
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Aged
MH  - *Coronary Artery Bypass
MH  - Female
MH  - Humans
MH  - Ischemia/mortality/pathology/physiopathology/*surgery
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve Insufficiency/mortality/pathology/physiopathology/*surgery
MH  - Postoperative Complications/diagnosis/mortality
MH  - Retrospective Studies
MH  - Severity of Illness Index
MH  - Treatment Outcome
MH  - Ventricular Function, Left
PMC - PMC6831358
EDAT- 2019/04/28 06:00
MHDA- 2019/05/29 06:00
PMCR- 2019/04/26
CRDT- 2019/04/28 06:00
PHST- 2019/04/28 06:00 [entrez]
PHST- 2019/04/28 06:00 [pubmed]
PHST- 2019/05/29 06:00 [medline]
PHST- 2019/04/26 00:00 [pmc-release]
AID - 00005792-201904260-00001 [pii]
AID - MD-D-18-07694 [pii]
AID - 10.1097/MD.0000000000014969 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2019 Apr;98(17):e14969. doi: 10.1097/MD.0000000000014969.