PMID- 31027509 OWN - NLM STAT- MEDLINE DCOM- 20200506 LR - 20240229 IS - 2046-4053 (Electronic) IS - 2046-4053 (Linking) VI - 8 IP - 1 DP - 2019 Apr 26 TI - The effects of aerobic, resistance, and meditative movement exercise on sleep in individuals with depression: protocol for a systematic review and network meta-analysis. PG - 105 LID - 10.1186/s13643-019-1018-4 [doi] LID - 105 AB - BACKGROUND: The main objective of this review is to assess the effects of aerobic, resistance, and meditative movement exercise on sleep quality in patients with unipolar depression. A secondary goal is to ascertain the effects on sleep duration, sleepiness, daytime functioning, use of hypnotics, and adverse events. METHODS: A systematic computerized search will be performed in the following online databases: PubMed, EMBASE (on Ovid), Cochrane Library, PsycINFO (on Ovid), SPORTDiscus (on EBSCOhost), CINHAL (on EBSCOhost), Clinicaltrials.gov , WHO International Clinical Trials Registry, OpenGrey, and ProQuest Dissertations and Theses. Bibliographies of all included studies as well as any other relevant reviews identified via the search will be screened. Randomized trials using aerobic, resistance, or meditative movement exercise interventions which target sleep as a primary or secondary outcome will be included. The primary outcome will be differences in sleep quality at post-intervention. Secondary outcomes will be adverse events, differences in sleep duration, daytime sleepiness and functioning, and the use of hypnotics at post-intervention. Two authors will independently screen the identified records. Disagreement will be resolved by consensus or if no consensus can be reached by adjudication of a designated third reviewer. Data extraction will be done independently by two authors using a standardized and piloted data extraction sheet. Bias in individual studies will be assessed using the revised Cochrane risk of bias tool. The certainty of evidence across all outcomes will be evaluated using the CINeMA (Confidence in Network Meta-Analysis) framework. A frequentist network meta-analysis will be conducted. The systematic review and network meta-analysis will be presented according to the PRISMA for Network Meta-Analyses (PRISMA-NMA) guideline. DISCUSSION: This systematic review and network meta-analysis will provide a synthesis of the currently available evidence concerning the effects of aerobic, resistance, and meditative movement exercises on sleep in patients with unipolar depression. Thereby, we hope to accelerate the consolidation of evidence and inform decision-makers on potential benefits and harms. SYSTEMATIC REVIEW REGISTRATION: The protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42019115705). FAU - Brupbacher, Gavin AU - Brupbacher G AUID- ORCID: 0000-0002-0140-6614 AD - Division of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Birsstrasse 320 B, 4052, Basel, Switzerland. gavin.brupbacher@unibas.ch. AD - Oberwaid AG, Rorschacher Strasse 311, 9016, St. Gallen, Switzerland. gavin.brupbacher@unibas.ch. FAU - Gerger, Heike AU - Gerger H AD - Division of Clinical Psychology and Psychotherapy, Faculty of Psychology, University of Basel, Missionsstrasse 62a, 4055, Basel, Switzerland. FAU - Wechsler, Monika AU - Wechsler M AD - University Medical Library Basel, Spiegelgasse 5, 4051, Basel, Switzerland. FAU - Zander-Schellenberg, Thea AU - Zander-Schellenberg T AD - Division of Clinical Psychology and Epidemiology, Faculty of Psychology, University of Basel, Missionsstrasse 62a, 4055, Basel, Switzerland. FAU - Straus, Doris AU - Straus D AD - Oberwaid AG, Rorschacher Strasse 311, 9016, St. Gallen, Switzerland. FAU - Porschke, Hildburg AU - Porschke H AD - Oberwaid AG, Rorschacher Strasse 311, 9016, St. Gallen, Switzerland. FAU - Gerber, Markus AU - Gerber M AD - Division of Sport and Psychosocial Health, Department of Sport, Exercise and Health, University of Basel, Birsstrasse 320 B, 4052, Basel, Switzerland. FAU - von Kanel, Roland AU - von Kanel R AD - Department of Consultation-Liaison Psychiatry and Psychosomatic Medicine, University Hospital Zurich, University of Zurich, Culmannstrasse 8, 8091, Zurich, Switzerland. FAU - Schmidt-Trucksass, Arno AU - Schmidt-Trucksass A AD - Division of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Birsstrasse 320 B, 4052, Basel, Switzerland. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190426 PL - England TA - Syst Rev JT - Systematic reviews JID - 101580575 SB - IM MH - Humans MH - *Depressive Disorder/therapy MH - *Exercise/psychology MH - *Meditation/psychology MH - *Network Meta-Analysis MH - *Resistance Training MH - *Sleep/physiology MH - Meta-Analysis as Topic MH - Systematic Reviews as Topic PMC - PMC6486698 OTO - NOTNLM OT - Aerobic OT - Depression OT - Exercise OT - Meditative movement OT - Network meta-analysis OT - Protocol OT - Randomized OT - Resistance OT - Sleep OT - Systematic review OT - Trial COIS- ETHICS APPROVAL AND CONSENT TO PARTICIPATE: Not applicable. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: Gavin Brupbacher is funded through an industry-sponsored PhD, provided by Oberwaid AG, St. Gallen, Switzerland. Dr. Doris Straus and Dr. Hildburg Porschke are employed by Oberwaid AG. Arno Schmidt-Trucksass and Roland von Kanel are on the scientific advisory board of the Oberwaid AG. All other authors declare no competing interests. PUBLISHER'S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. EDAT- 2019/04/28 06:00 MHDA- 2020/05/06 06:00 PMCR- 2019/04/26 CRDT- 2019/04/28 06:00 PHST- 2018/04/17 00:00 [received] PHST- 2019/04/05 00:00 [accepted] PHST- 2019/04/28 06:00 [entrez] PHST- 2019/04/28 06:00 [pubmed] PHST- 2020/05/06 06:00 [medline] PHST- 2019/04/26 00:00 [pmc-release] AID - 10.1186/s13643-019-1018-4 [pii] AID - 1018 [pii] AID - 10.1186/s13643-019-1018-4 [doi] PST - epublish SO - Syst Rev. 2019 Apr 26;8(1):105. doi: 10.1186/s13643-019-1018-4.