PMID- 31031656 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1664-0640 (Print) IS - 1664-0640 (Electronic) IS - 1664-0640 (Linking) VI - 10 DP - 2019 TI - Impact of Psychotherapy in Psychosis: A Retrospective Case Control Study. PG - 204 LID - 10.3389/fpsyt.2019.00204 [doi] LID - 204 AB - Background: The need for psychological therapies for psychosis has become apparent since long-term antipsychotic drug treatment has a range of adverse side effects, with moderate therapeutic effects at best. Aims: To investigate whether the psychotherapeutic approach, dialogue therapy (DT) is associated with improvements of symptoms and functioning beyond standard psychiatric treatment (ST) in both schizophrenia and other psychosis. Methods: A retrospective case-control design, comparing 54 patients with different psychoses who received DT with 54 patients in a control group receiving ST was carried out. The groups were matched on diagnosis, age, sex, and treatment start. Outcome measures were Global assessment of functioning (GAF) scores, medications at follow up, and hospital stays after completed outpatient treatment. Results: Mean time in treatment from inclusion to follow-up was 3 years and 5 months. At follow-up, GAF functioning (GAF-F) and GAF symptom (GAF-S) scores both were significantly higher in the DT group than the ST group. Effect sizes (Cohen's d) were large; 1.8 for GAF-S and 2.1 for GAF-F. At follow-up, the use of psychoactive drugs was significantly reduced despite a shorter time in psychotherapy in the DT group compared to the ST group. Days of hospitalizations after end of treatment in the study period were significantly reduced in both groups compared to the period before start of treatment. Conclusions: The findings from this exploratory study are consistent with the possibility that dialogue therapy may lead to improvements in symptoms and functioning compared to standard treatment in psychosis. FAU - Haram, Annbjorg AU - Haram A AD - Department of Psychiatry, More and Romsdal Hospital Trust, Alesund, Norway. FAU - Fosse, Roar AU - Fosse R AD - Division of Mental Health and Addiction, Vestre Viken Hospital Trust, Drammen, Norway. FAU - Jonsbu, Egil AU - Jonsbu E AD - Department of Psychiatry, More and Romsdal Hospital Trust, Alesund, Norway. AD - Department of Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway. FAU - Hole, Torstein AU - Hole T AD - Clinic of Medicine and Rehabilitation, More and Romsdal Hospital Trust, Alesund, Norway. AD - Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway. LA - eng PT - Journal Article DEP - 20190411 PL - Switzerland TA - Front Psychiatry JT - Frontiers in psychiatry JID - 101545006 PMC - PMC6470395 OTO - NOTNLM OT - antipsychotic medication OT - dialogue therapy OT - global assessment of functioning OT - psychosis OT - psychotherapy EDAT- 2019/04/30 06:00 MHDA- 2019/04/30 06:01 PMCR- 2019/04/11 CRDT- 2019/04/30 06:00 PHST- 2019/01/08 00:00 [received] PHST- 2019/03/20 00:00 [accepted] PHST- 2019/04/30 06:00 [entrez] PHST- 2019/04/30 06:00 [pubmed] PHST- 2019/04/30 06:01 [medline] PHST- 2019/04/11 00:00 [pmc-release] AID - 10.3389/fpsyt.2019.00204 [doi] PST - epublish SO - Front Psychiatry. 2019 Apr 11;10:204. doi: 10.3389/fpsyt.2019.00204. eCollection 2019.