PMID- 31039569
OWN - NLM
STAT- MEDLINE
DCOM- 20200220
LR  - 20200220
IS  - 1423-0399 (Electronic)
IS  - 0042-1138 (Linking)
VI  - 103
IP  - 2
DP  - 2019
TI  - The Effect of Intravesical Prostatic Protrusion in Patients with Benign Prostatic 
      Hyperplasia: Controlled, Clinical Study.
PG  - 180-186
LID - 10.1159/000499437 [doi]
AB  - BACKGROUND: Although prostate cancer releases more prostate-specific antigen 
      (PSA) per unit of prostate volume (PV), data are limited regarding the 
      association between intravesical prostatic protrusion (IPP) and the PSA level. 
      OBJECTIVES: The study aim was to evaluate the IPP effect in patients with benign 
      prostatic hyperplasia. METHOD: This study included patients with (n = 119) and 
      without (n = 121) IPP. The age, International Prostate Symptom Score (IPSS), PSA 
      level, maximum and average flow rates, PV, hematuria, urinary retention, and 
      post-void residual (PVR) volume were compared between the 2 groups. RESULTS: The 
      mean ages were similar between the 2 groups (66.56 +/- 8.67 and 66.92 +/- 8.7 years, 
      respectively, p = 0.747), and there were no statistically significant differences 
      in the IPSS, maximum and average flow rates, hematuria, PVR volume, and urinary 
      retention means (p > 0.05). However, the IPP patients had lower total PSA (tPSA) 
      and free PSA (fPSA) levels than those without IPP (3.55 [4.18] vs. 5.26 [5.24] 
      ng/mL, p = 0.013 and 0.7 [1.09] vs. 1.05 [1.23] ng/mL, p = 0.029, respectively). 
      Moreover, there were strong positive correlations between the IPP grade and the 
      tPSA and fPSA levels (r = 0.262, p = 0.001 and r = 0.254, p = 0.002 
      respectively). CONCLUSIONS: This study demonstrated that IPP results in a 
      decreased PSA level, even with a higher PV.
CI  - (c) 2019 S. Karger AG, Basel.
FAU - Kadihasanoglu, Mustafa
AU  - Kadihasanoglu M
AD  - Department of Urology, Istanbul Training and Research Hospital, Istanbul, Turkey, 
      kadihasanoglu@gmail.com.
FAU - Aydin, Mustafa
AU  - Aydin M
AD  - Department of Urology, Samsun Training and Research Hospital, Samsun, Turkey.
FAU - Taskiran, Mehmet
AU  - Taskiran M
AD  - MMT Amerikan Hastanesi, Gaziantep, Turkey.
FAU - Kendirci, Muammer
AU  - Kendirci M
AD  - Department of Urology, Liv Hospital Ulus, Istinye University, Faculty of 
      Medicine, Istanbul, Turkey.
LA  - eng
PT  - Clinical Study
PT  - Journal Article
DEP - 20190430
PL  - Switzerland
TA  - Urol Int
JT  - Urologia internationalis
JID - 0417373
SB  - IM
MH  - Aged
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prostate/*diagnostic imaging/*pathology
MH  - Prostatic Hyperplasia/*diagnostic imaging/*pathology
MH  - Retrospective Studies
MH  - Ultrasonography
MH  - Urinary Bladder/diagnostic imaging/pathology
OTO - NOTNLM
OT  - Benign prostatic hyperplasia
OT  - Intravesical prostatic protrusion
OT  - Prostate
OT  - Prostate specific antigen
OT  - Ultrasound
OT  - Uroflowmetry
EDAT- 2019/05/01 06:00
MHDA- 2020/02/23 06:00
CRDT- 2019/05/01 06:00
PHST- 2018/10/15 00:00 [received]
PHST- 2019/02/04 00:00 [accepted]
PHST- 2019/05/01 06:00 [pubmed]
PHST- 2020/02/23 06:00 [medline]
PHST- 2019/05/01 06:00 [entrez]
AID - 000499437 [pii]
AID - 10.1159/000499437 [doi]
PST - ppublish
SO  - Urol Int. 2019;103(2):180-186. doi: 10.1159/000499437. Epub 2019 Apr 30.