PMID- 3105117
OWN - NLM
STAT- MEDLINE
DCOM- 19870511
LR  - 20190727
IS  - 0040-8727 (Print)
IS  - 0040-8727 (Linking)
VI  - 150
IP  - 4
DP  - 1986 Dec
TI  - Antitumor activity of lipopolysaccharide in tumor-bearing mice pretreated with 
      BCG.
PG  - 391-9
AB  - The antitumor activity of lipopolysaccharide (LPS) was investigated in 
      BCG-treated mice. C3H/He mice and CDF1 mice were injected with BCG and then were 
      inoculated with syngeneic mouse hepatoma MH134 and mastocytoma P815 respectively. 
      Hemorrhagic necrosis and retarded growth of tumor were observed after an 
      intravenous (i.v.) injection of LPS, when tumor cells had been inoculated 
      subcutaneously (s.c.). However an intraperitoneal (i.p.) injection of BCG plus 
      LPS did not increase the mean survival time of mice that had been inoculated with 
      tumor cells i.p. Sera from mice that had been treated with BCG plus LPS i.v. were 
      cytotoxic for cultured tumor cells. These results seemed to indicate that 
      growth-inhibitory effects of LPS on tumors inoculated s.c. were mediated by a 
      humoral factor.
FAU - Sato, H
AU  - Sato H
FAU - Ito, M
AU  - Ito M
FAU - Abe, T
AU  - Abe T
FAU - Kumano, N
AU  - Kumano N
FAU - Motomiya, M
AU  - Motomiya M
FAU - Konno, K
AU  - Konno K
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Tohoku J Exp Med
JT  - The Tohoku journal of experimental medicine
JID - 0417355
RN  - 0 (Lipopolysaccharides)
SB  - IM
MH  - Animals
MH  - *Immunotherapy
MH  - Lipopolysaccharides/*therapeutic use
MH  - Liver Neoplasms, Experimental/*therapy
MH  - Male
MH  - Mast-Cell Sarcoma/*therapy
MH  - Mice
MH  - Mice, Inbred C3H
MH  - Mycobacterium bovis/*immunology
EDAT- 1986/12/01 00:00
MHDA- 1986/12/01 00:01
CRDT- 1986/12/01 00:00
PHST- 1986/12/01 00:00 [pubmed]
PHST- 1986/12/01 00:01 [medline]
PHST- 1986/12/01 00:00 [entrez]
AID - 10.1620/tjem.150.391 [doi]
PST - ppublish
SO  - Tohoku J Exp Med. 1986 Dec;150(4):391-9. doi: 10.1620/tjem.150.391.