PMID- 31051170 OWN - NLM STAT- MEDLINE DCOM- 20200602 LR - 20200602 IS - 1931-3543 (Electronic) IS - 0012-3692 (Linking) VI - 156 IP - 5 DP - 2019 Nov TI - Costs of Workplace Productivity Loss in Patients With Fibrotic Interstitial Lung Disease. PG - 887-895 LID - S0012-3692(19)30885-2 [pii] LID - 10.1016/j.chest.2019.04.016 [doi] AB - BACKGROUND: Fibrotic interstitial lung diseases (ILDs) are highly morbid chronic disorders that frequently occur in working age individuals. The goal of this study was to determine workplace productivity loss, its determinants, and its estimated costs in patients with fibrotic ILD. METHODS: Patients with idiopathic pulmonary fibrosis, chronic hypersensitivity pneumonitis, idiopathic nonspecific interstitial pneumonia, or unclassifiable ILD were identified from the six-center Canadian Registry for Pulmonary Fibrosis (CARE-PF). The Work Productivity and Activity Impairment questionnaire was used to determine health-related productivity loss. Independent predictors of low workplace productivity were identified by using multivariate regression. Patient data were compared with Canadian population census data. The average productivity loss (hours per week) and the individual's hourly wage were used to estimate the costs of productivity loss. RESULTS: Of 650 eligible patients, 148 (23%) were employed. Productivity loss was reported by 55% of employed patients with an average productivity loss of 7.8 +/- 0.9 h per week (2.3 +/- 0.6 h per week related to absenteeism and 5.5 +/- 0.6 h per week related to presenteeism). Employment among patients with ILD aged 25 to 54 years was 23% lower than the age- and sex-matched general Canadian population (60% vs 83%; P < .001). Employment among patients with ILD aged >/= 55 years was 18% lower than in the age- and sex-matched population (20% vs 38%; P < .001). Dyspnea and cough were independent predictors of workplace productivity loss. Estimated annual costs of productivity loss were 11,610 Canadian dollars per employee with ILD. CONCLUSIONS: Workplace productivity loss is common in fibrotic ILD, strongly correlated with symptom severity, and associated with significant cost. CI - Copyright (c) 2019 The Authors. Published by Elsevier Inc. All rights reserved. FAU - Algamdi, Mohmmed AU - Algamdi M AD - Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, Canada; Department of Pulmonary and Critical Care Medicine, King Fahad Medical City, Riyadh, Saudi Arabia. FAU - Sadatsafavi, Mohsen AU - Sadatsafavi M AD - Respiratory Evaluation Sciences Program, Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, BC, Canada. FAU - Fisher, Jolene H AU - Fisher JH AD - Department of Medicine, University of Toronto, Toronto, ON, Canada. FAU - Morisset, Julie AU - Morisset J AD - Departement de Medecine, Centre Hospitalier de l'Universite de Montreal, Montreal, QC, Canada. FAU - Johannson, Kerri A AU - Johannson KA AD - Department of Medicine, University of Calgary, Calgary, AB, Canada. FAU - Fell, Charlene D AU - Fell CD AD - Department of Medicine, University of Calgary, Calgary, AB, Canada. FAU - Kolb, Martin AU - Kolb M AD - Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada. FAU - Manganas, Helene AU - Manganas H AD - Departement de Medecine, Centre Hospitalier de l'Universite de Montreal, Montreal, QC, Canada. FAU - Cox, Gerard AU - Cox G AD - Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada. FAU - Gershon, Andrea S AU - Gershon AS AD - Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Toronto, ON, Canada. FAU - Halayko, Andrew J AU - Halayko AJ AD - Departments of Internal Medicine and Physiology and Pathophysiology, University of Manitoba, Winnipeg, MB, Canada. FAU - Hambly, Nathan AU - Hambly N AD - Department of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, ON, Canada. FAU - Khalil, Nasreen AU - Khalil N AD - Department of Medicine, University of British Columbia, Vancouver, BC, Canada. FAU - Shapera, Shane AU - Shapera S AD - Department of Medicine, University of Toronto, Toronto, ON, Canada. FAU - To, Teresa AU - To T AD - Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada. FAU - Wilcox, Pearce G AU - Wilcox PG AD - Department of Medicine, University of British Columbia, Vancouver, BC, Canada. FAU - Guler, Sabina AU - Guler S AD - Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, Canada. FAU - Ryerson, Christopher J AU - Ryerson CJ AD - Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Centre for Heart Lung Innovation, St. Paul's Hospital, Vancouver, BC, Canada. Electronic address: chris.ryerson@hli.ubc.ca. LA - eng PT - Journal Article DEP - 20190430 PL - United States TA - Chest JT - Chest JID - 0231335 SB - IM MH - *Absenteeism MH - Adult MH - Aged MH - Alveolitis, Extrinsic Allergic/economics MH - Canada MH - Chronic Disease MH - *Efficiency MH - Employment/*statistics & numerical data MH - Female MH - Humans MH - Idiopathic Interstitial Pneumonias/economics MH - Idiopathic Pulmonary Fibrosis/economics MH - Logistic Models MH - Lung Diseases, Interstitial/*economics MH - Male MH - Middle Aged MH - Presenteeism/*economics OTO - NOTNLM OT - economics OT - hypersensitivity pneumonia OT - idiopathic pulmonary fibrosis OT - interstitial lung disease EDAT- 2019/05/06 06:00 MHDA- 2020/06/03 06:00 CRDT- 2019/05/04 06:00 PHST- 2019/01/22 00:00 [received] PHST- 2019/04/05 00:00 [revised] PHST- 2019/04/10 00:00 [accepted] PHST- 2019/05/06 06:00 [pubmed] PHST- 2020/06/03 06:00 [medline] PHST- 2019/05/04 06:00 [entrez] AID - S0012-3692(19)30885-2 [pii] AID - 10.1016/j.chest.2019.04.016 [doi] PST - ppublish SO - Chest. 2019 Nov;156(5):887-895. doi: 10.1016/j.chest.2019.04.016. Epub 2019 Apr 30.