PMID- 31060188
OWN - NLM
STAT- MEDLINE
DCOM- 20190814
LR  - 20190814
IS  - 0253-3758 (Print)
IS  - 0253-3758 (Linking)
VI  - 47
IP  - 4
DP  - 2019 Apr 24
TI  - [Feasibility and efficacy of percutaneous closure of paravalvuar leak in patients 
      after heart valve replacement surgery using Amplatzer vascular plug Ⅲ].
PG  - 291-296
LID - 10.3760/cma.j.issn.0253-3758.2019.04.006 [doi]
AB  - Objective: To investigate the feasibility and efficacy of percutaneous closure of 
      paravalvuar leak (PVL) in patients after heart valve replacement surgery using 
      Amplatzer vascular plug Ⅲ (AVP Ⅲ). Methods: In this retrospective study, 
      consecutive PVL patients after heart valve replacement surgery receiving 
      percutaneous closure with AVP Ⅲ in Beijing Anzhen hospital between March 2017 and 
      October 2018 (n=21) were enrolled.The preoperative and intraoperative data and 
      short-and mid-term outcome results were analyzed. Results: Theage of patients in 
      this cohort was (54.9+/-11.7) years, and there were 12 (57.1%) male patients. There 
      were 8 patients (38.1%) post mitral valve replacement, 4 patients (19.0%) post 
      aortic valve replacement and 9 patients (42.9%) post double valves 
      replacements.There were 14 cases (66.7%) of mitral valve PVL,6 cases (28.6%) of 
      aortic valve PVL, and 1 case (4.8%) of double valves PVL.Successful device 
      deployment was accomplished in 18 defects from 17 PVL patients. Technical 
      successful rate of mitral valve PVL closure and aortic valve PVL closure was 
      12/15 and 6/7,respectively. One patient received surgical repair due to 
      procedure-induced femoral pseudoaneurysm.There were 17 cases of severe PVL and 1 
      case of moderate PVL before procedure, and there were 2 cases of moderate PVL, 6 
      cases mild PVL, and PVL disappeared in 10 cases after procedure (P<0.01 vs. 
      pre-procedure). The follow-up time was (8.3+/-4.7) months. There were 10 cases 
      (58.8%) of New York Heart Association (NYHA) function grade Ⅲ and 7 cases (41.2%) 
      of NYHA function grade Ⅳ before procedure, and there were 12 cases of NYHA 
      function grade Ⅰ(70.6%) and 5 cases (29.4%) of NYHA function grade Ⅱ post 
      procedure (P<0.01). Post procedure, there was no displacement of the occluder and 
      heart valve movement was not affected,and there was no new hemolysis or hemolysis 
      worsening. Conclusion: Percutaneous closure of PVL in patients after heart valve 
      replacement surgery with AVP Ⅲ is feasible, and associated with favorable 
      short-and mid-term clinical outcomes.
FAU - Pu, J Z
AU  - Pu JZ
AD  - Interventional Department, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing Institute of Heart Lung and Vascular Disease, Beijing 100029, China.
FAU - Ke, Y T
AU  - Ke YT
AD  - Echocardiography Department, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing Institute of Heart Lung and Vascular Disease, Beijing 100029, China.
FAU - Huang, L J
AU  - Huang LJ
AD  - Interventional Department, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing Institute of Heart Lung and Vascular Disease, Beijing 100029, China.
FAU - Zhao, H L
AU  - Zhao HL
AD  - Cardiac Surgery Department, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing Institute of Heart Lung and Vascular Disease, Beijing 100029, China.
FAU - Zhang, C
AU  - Zhang C
AD  - Echocardiography Department, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing Institute of Heart Lung and Vascular Disease, Beijing 100029, China.
FAU - Wu, W H
AU  - Wu WH
AD  - Interventional Department, Beijing Anzhen Hospital, Capital Medical University, 
      Beijing Institute of Heart Lung and Vascular Disease, Beijing 100029, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhonghua Xin Xue Guan Bing Za Zhi
JT  - Zhonghua xin xue guan bing za zhi
JID - 7910682
MH  - *Cardiac Catheterization
MH  - *Heart Valve Prosthesis
MH  - *Heart Valve Prosthesis Implantation
MH  - Humans
MH  - Male
MH  - Prosthesis Failure
MH  - Retrospective Studies
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Heart valve diseases
OT  - Paravalvular leak
OT  - Vascular plug
EDAT- 2019/05/08 06:00
MHDA- 2019/08/15 06:00
CRDT- 2019/05/07 06:00
PHST- 2019/05/07 06:00 [entrez]
PHST- 2019/05/08 06:00 [pubmed]
PHST- 2019/08/15 06:00 [medline]
AID - 10.3760/cma.j.issn.0253-3758.2019.04.006 [doi]
PST - ppublish
SO  - Zhonghua Xin Xue Guan Bing Za Zhi. 2019 Apr 24;47(4):291-296. doi: 
      10.3760/cma.j.issn.0253-3758.2019.04.006.