PMID- 31061613 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220408 IS - 1319-0164 (Print) IS - 2213-7475 (Electronic) IS - 1319-0164 (Linking) VI - 27 IP - 4 DP - 2019 May TI - Evaluation of community pharmacists' knowledge about drug-drug interaction in Central Saudi Arabia. PG - 463-466 LID - 10.1016/j.jsps.2019.01.008 [doi] AB - INTRODUCTION: Although all implemented and ongoing initiatives, drug-drug interactions (DDIs) are still a global problem. Most published studies about DDIs in Saudi Arabia are carried out in hospital settings. In addition, assessing the knowledge of drug interactions in Saudi Arabia is limited. The aim of our study is to evaluate the knowledge of potential common drug-drug interactions among community pharmacists particularly in Saudi Arabia. METHODOLOGY: A crosses-sectional study utilizing a self- administered questionnaire was conducted among community pharmacy in Riyadh city Saudi Arabia. DDIs' knowledge was assessed by 26 drug pairs. Community pharmacists were asked to select the DDIs as "contraindication", "may be used together with monitoring", "no interaction" and "not sure". RESULTS: A total of 283 of community pharmacists completed the survey with response rate of 80.9%. Among the 26 drug pairs only 5 of them were identified correctly by most of the participants. To add more 3 out of the 5 pairs had a cutoff of less than 10% between the correct and wrong answer, meaning there still a majority that couldn't identify the correct answer. All the 26 pairs had a statistically significant difference between the correct and incorrect answer. CONCLUSION: The results of this study showed that knowledge of community pharmacists about DDIs was inadequate. Community pharmacist should have specific courses in drug interactions to cover the most possible interactions that can be seen in this setting. FAU - Alrabiah, Ziyad AU - Alrabiah Z AD - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. FAU - Alhossan, Abdulaziz AU - Alhossan A AD - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. FAU - Alghadeer, Sultan M AU - Alghadeer SM AD - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. FAU - Wajid, Syed AU - Wajid S AD - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. FAU - Babelghaith, Salmeen D AU - Babelghaith SD AD - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. FAU - Al-Arifi, Mohamed N AU - Al-Arifi MN AD - Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia. LA - eng PT - Journal Article DEP - 20190107 PL - Saudi Arabia TA - Saudi Pharm J JT - Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society JID - 9705695 PMC - PMC6488823 OTO - NOTNLM OT - Community pharmacist OT - Drug-drug interaction EDAT- 2019/05/08 06:00 MHDA- 2019/05/08 06:01 PMCR- 2019/01/07 CRDT- 2019/05/08 06:00 PHST- 2018/03/13 00:00 [received] PHST- 2019/01/05 00:00 [accepted] PHST- 2019/05/08 06:00 [entrez] PHST- 2019/05/08 06:00 [pubmed] PHST- 2019/05/08 06:01 [medline] PHST- 2019/01/07 00:00 [pmc-release] AID - S1319-0164(19)30009-X [pii] AID - 10.1016/j.jsps.2019.01.008 [doi] PST - ppublish SO - Saudi Pharm J. 2019 May;27(4):463-466. doi: 10.1016/j.jsps.2019.01.008. Epub 2019 Jan 7.