PMID- 31073433
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2146-4618 (Print)
IS  - 2146-4626 (Electronic)
IS  - 2146-4626 (Linking)
VI  - 6
IP  - 2
DP  - 2017 Jun
TI  - Childhood Obesity and Extracorporeal Membrane Oxygenation: Special Considerations 
      for Successful Outcomes.
PG  - 109-116
LID - 10.1055/s-0036-1584681 [doi]
AB  - The effects of obesity on venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) outcomes in pediatric population are unknown. We performed 
      retrospective analysis of 41 children (age 2-18 years) undergoing VA-ECMO. The 
      percentage difference between actual body weight and lean body weight, referred 
      to as Deltamass, was calculated. Ratios of Deltamass to ECMO flow were calculated at 4 
      and 24 hours. In patients with Deltamass:flow >/= 0.1 at 4 hours, higher 24-hour 
      lactates (20.0 vs. 14.5 mg/dL; p = 0.002) and inotrope scores (17.3 vs. 11.2; 
      p = 0.015) were observed. However, elevated Deltamass:flow was not associated with 
      mortality, and in-hospital mortality rates between groups were similar (53 vs. 
      45%; p = 0.647). In obese pediatric patients requiring VA-ECMO, increased flow is 
      necessary to avoid complications of hypoperfusion and related complications.
FAU - Iyengar, Amit
AU  - Iyengar A
AD  - David Geffen School of Medicine, University of California, Los Angeles, 
      California, United States.
FAU - Zhu, Allen
AU  - Zhu A
AD  - David Geffen School of Medicine, University of California, Los Angeles, 
      California, United States.
FAU - Samson, Jessica
AU  - Samson J
AD  - Department of Perfusion Services, University of California, Los Angeles, 
      California, United States.
FAU - Reemtsen, Brian
AU  - Reemtsen B
AD  - Department of Cardiothoracic Surgery, Ronald Reagan Medical Center, University of 
      California, Los Angeles, California, United States.
FAU - Biniwale, Reshma
AU  - Biniwale R
AD  - Department of Cardiothoracic Surgery, Ronald Reagan Medical Center, University of 
      California, Los Angeles, California, United States.
LA  - eng
PT  - Journal Article
DEP - 20160624
PL  - Germany
TA  - J Pediatr Intensive Care
JT  - Journal of pediatric intensive care
JID - 101592756
PMC - PMC6260271
OTO - NOTNLM
OT  - VA-ECMO
OT  - children
OT  - obesity
EDAT- 2017/06/01 00:00
MHDA- 2017/06/01 00:01
PMCR- 2017/06/01
CRDT- 2019/05/11 06:00
PHST- 2015/10/07 00:00 [received]
PHST- 2016/03/19 00:00 [accepted]
PHST- 2019/05/11 06:00 [entrez]
PHST- 2017/06/01 00:00 [pubmed]
PHST- 2017/06/01 00:01 [medline]
PHST- 2017/06/01 00:00 [pmc-release]
AID - 1500013 [pii]
AID - 10.1055/s-0036-1584681 [doi]
PST - ppublish
SO  - J Pediatr Intensive Care. 2017 Jun;6(2):109-116. doi: 10.1055/s-0036-1584681. 
      Epub 2016 Jun 24.