PMID- 31076317 OWN - NLM STAT- MEDLINE DCOM- 20201106 LR - 20201106 IS - 0929-6646 (Print) IS - 0929-6646 (Linking) VI - 119 IP - 2 DP - 2020 Feb TI - Management of polypoidal choroidal vasculopathy: Experts consensus in Taiwan. PG - 569-576 LID - S0929-6646(18)30845-3 [pii] LID - 10.1016/j.jfma.2019.04.012 [doi] AB - Polypoidal choroidal vasculopathy (PCV) is a prevalent retinal disease predominantly occurs in Asians that shares some similarities seen in neovascular age-related macular degeneration. Recent large multicenter clinical trials on intravitreal anti-vascular endothelial growth factor (VEGF) agents and photodynamic therapy (PDT) have shed lights on the management of PCV. The Taiwan National Health Insurance had granted limited anti-VEGF agents and PDT for patients with PCV after the approval of required data submission, especially fundus angiography, optical coherence tomography, and visual acuity. In order to best utilize these limited resources for the patients, an expert meeting was held to provide updated Taiwan consensus recommendations for the management of PCV, including initial therapy selection, assessment of treatment response, re-treatment/rescue treatment, and determination of treatment extension/follow-up schedule. An algorithm for treatment allocation under both initial and re-treatment setting was proposed. Further mechanistic and clinical studies are required to investigate the prognostic factors and optimal treatment protocols that will improve healthcare quality and reduce burden of disease and treatment for patients with PCV. CI - Copyright (c) 2019 Formosan Medical Association. Published by Elsevier B.V. All rights reserved. FAU - Chen, Lee-Jen AU - Chen LJ AD - Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan. FAU - Cheng, Cheng-Kuo AU - Cheng CK AD - Department of Ophthalmology, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, National Taiwan University, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan. FAU - Yeung, Ling AU - Yeung L AD - Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. FAU - Yang, Chang-Hao AU - Yang CH AD - Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. FAU - Chen, Shih-Jen AU - Chen SJ AD - Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan. Electronic address: sjchen@vghtpe.gov.tw. CN - Taiwan PCV consensus group LA - eng PT - Journal Article PT - Review DEP - 20190507 PL - Singapore TA - J Formos Med Assoc JT - Journal of the Formosan Medical Association = Taiwan yi zhi JID - 9214933 RN - 0 (Angiogenesis Inhibitors) RN - 0 (VEGFA protein, human) RN - 0 (Vascular Endothelial Growth Factor A) SB - IM MH - Angiogenesis Inhibitors/*administration & dosage MH - Choroid Diseases/*diagnosis/*drug therapy MH - Consensus MH - Disease Management MH - Fluorescein Angiography MH - Fundus Oculi MH - Humans MH - Intravitreal Injections MH - Macular Degeneration/*diagnosis/*drug therapy MH - Photochemotherapy MH - Polyps/diagnosis/drug therapy MH - Taiwan MH - Tomography, Optical Coherence MH - Vascular Endothelial Growth Factor A/antagonists & inhibitors MH - Visual Acuity OTO - NOTNLM OT - Choroidal neovascularization OT - PCV OT - Photodynamic therapy OT - Vascular endothelial growth factors OT - Wet age-related macular degeneration FIR - Chen, Jiann-Torng IR - Chen JT IRAD- Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan. FIR - Chen, Lee-Jen IR - Chen LJ IRAD- Department of Ophthalmology, Mackay Memorial Hospital, Taipei, Taiwan. FIR - Chen, San-Ni IR - Chen SN IRAD- Department of Ophthalmology, Changhua Christian Hospital, Changhua, Taiwan. FIR - Chen, Wen-Lu IR - Chen WL IRAD- Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan. FIR - Cheng, Cheng-Kuo IR - Cheng CK IRAD- Department of Ophthalmology, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, National Taiwan University, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan. FIR - Hsu, Sheng-Min IR - Hsu SM IRAD- Department of Ophthalmology, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan. FIR - Hwang, De-Kuang IR - Hwang DK IRAD- Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine National Yang-Ming University School of Medicine, Taipei, Taiwan. FIR - Lai, Chi-Chun IR - Lai CC IRAD- Department of Ophthalmology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. FIR - Lai, Chien-Hsiung IR - Lai CH IRAD- College of Medicine, Chang Gung University, Taoyuan, Taiwan; Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi, Taiwan; Department of Nursing, Chang Gung University of Science and Technology, Chiayi, Taiwan. FIR - Lee, Fenq-Lih IR - Lee FL IRAD- Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan. FIR - Yang, Chang-Hao IR - Yang CH IRAD- Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. FIR - Yang, Chung-May IR - Yang CM IRAD- Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan. FIR - Yeung, Ling IR - Yeung L IRAD- Department of Ophthalmology, Chang Gung Memorial Hospital, Keelung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. FIR - Wu, Tsung-Tien IR - Wu TT IRAD- Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; Department of Ophthalmology, School of Medicine, National Yang-Ming University School of Medicine Taipei, Taiwan. FIR - Chen, Shih-Jen IR - Chen SJ IRAD- Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Ophthalmology, School of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan. EDAT- 2019/05/12 06:00 MHDA- 2020/11/11 06:00 CRDT- 2019/05/12 06:00 PHST- 2018/11/29 00:00 [received] PHST- 2019/04/08 00:00 [revised] PHST- 2019/04/18 00:00 [accepted] PHST- 2019/05/12 06:00 [pubmed] PHST- 2020/11/11 06:00 [medline] PHST- 2019/05/12 06:00 [entrez] AID - S0929-6646(18)30845-3 [pii] AID - 10.1016/j.jfma.2019.04.012 [doi] PST - ppublish SO - J Formos Med Assoc. 2020 Feb;119(2):569-576. doi: 10.1016/j.jfma.2019.04.012. Epub 2019 May 7.