PMID- 31078576 OWN - NLM STAT- MEDLINE DCOM- 20200525 LR - 20200525 IS - 1878-5921 (Electronic) IS - 0895-4356 (Linking) VI - 113 DP - 2019 Sep TI - Minimal clinically important difference of commonly used hip-, knee-, foot-, and ankle-specific questionnaires: a systematic review. PG - 44-57 LID - S0895-4356(18)30938-7 [pii] LID - 10.1016/j.jclinepi.2019.04.017 [doi] AB - OBJECTIVE: Minimal clinically important difference (MCID) has become the most important psychometric factor for interpreting change in individual's responses over time from the patient's perspective, evaluating study results and planning sample sizes. The purpose was to synthesize and critically appraise MCID of the most frequently used hip-, knee-, foot-, and ankle-specific patient-reported outcomes (PROs). STUDY DESIGN AND SETTING: A search was conducted on PubMed, Cochrane Library, and Web of Science from each site's respective inception through January 2019 for MCID in 25 PROs. The studies reporting their results with anchor-based method were included. RESULTS: 228 full-text articles were assessed for eligibility, and 48 were included in the final evaluation. Our synthesis provides a comprehensive assessment of MCID for 16 disease or joint specific PROs. MCID of the Western Ontario and McMaster Universities Index (33.3%), International Knee Documentation Committee Subjective Knee Form (14.5%) and Knee Injury, and Osteoarthritis Outcome Score (14.5%) was found to be the most commonly presented PROs. The studies mainly (85%) used the receiver operating curve analysis to elicit MCID. CONCLUSION: MCID is increasingly used as a measure of patient's improvement. However, MCID varied based on the analytic methods, study population, type of disease, the baseline status, change in values and treatments, and patient demographics. Therefore, it should be interpreted with caution. CI - Copyright (c) 2019 Elsevier Inc. All rights reserved. FAU - Celik, Derya AU - Celik D AD - Division of Physiotherapy and Rehabilitation, Istanbul University-Cerrahpasa, Faculty of Health Sciences, Istanbul, Turkey. Electronic address: ptderya@hotmail.com. FAU - Coban, Ozge AU - Coban O AD - Division of Physiotherapy and Rehabilitation, Ankara Yildirim Beyazit University, Faculty of Health Sciences, Ankara, Turkey. FAU - Kilicoglu, Onder AU - Kilicoglu O AD - Department of Orthopaedics and Traumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20190509 PL - United States TA - J Clin Epidemiol JT - Journal of clinical epidemiology JID - 8801383 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Ankle Injuries/*diagnosis MH - *Disability Evaluation MH - Female MH - Foot Diseases/*diagnosis MH - Humans MH - Male MH - Middle Aged MH - *Minimal Clinically Important Difference MH - Ontario MH - Osteoarthritis, Hip/*diagnosis MH - Osteoarthritis, Knee/*diagnosis MH - Patient Reported Outcome Measures MH - Surveys and Questionnaires/*standards/statistics & numerical data OTO - NOTNLM OT - Lower extremity outcome scores OT - MCID OT - Minimum important difference OT - Patient-reported outcomes EDAT- 2019/05/13 06:00 MHDA- 2020/05/26 06:00 CRDT- 2019/05/13 06:00 PHST- 2018/10/20 00:00 [received] PHST- 2019/03/27 00:00 [revised] PHST- 2019/04/25 00:00 [accepted] PHST- 2019/05/13 06:00 [pubmed] PHST- 2020/05/26 06:00 [medline] PHST- 2019/05/13 06:00 [entrez] AID - S0895-4356(18)30938-7 [pii] AID - 10.1016/j.jclinepi.2019.04.017 [doi] PST - ppublish SO - J Clin Epidemiol. 2019 Sep;113:44-57. doi: 10.1016/j.jclinepi.2019.04.017. Epub 2019 May 9.