PMID- 31085749 OWN - NLM STAT- MEDLINE DCOM- 20190827 LR - 20210214 IS - 2191-0308 (Electronic) IS - 0048-7554 (Linking) VI - 34 IP - 2 DP - 2019 Jun 26 TI - Obstructive sleep apnea: personal, societal, public health, and legal implications. PG - 153-169 LID - 10.1515/reveh-2018-0068 [doi] AB - Introduction Obstructive sleep apnea (OSA) is a widely prevalent sleep-related breathing disorder, which leads to several life-threatening diseases. OSA has systemic effects on various organ systems. Untreated OSA is associated with long-term health consequences including hypertension, heart disease, diabetes, depression, metabolic disorders, and stroke. In addition, untreated OSA is reported to be associated with cognitive dysfunction, impaired productivity at the workplace and in an increased risk of motor vehicle accidents (MVAs) resulting in injury and fatality. Other consequences of OSA include, but are not limited to, impaired vigilance, daytime somnolence, performance deficits, morning headaches, mood disturbances, neurobehavioral impairments, and general malaise. Additionally, OSA has become an economic burden on most health systems all over the world. Many driving license regulations have been developed to reduce MVAs among OSA patients. Methods Studies of the personal, societal, public health, and legal aspects of OSA are reviewed. Data were collected through the following databases: MEDLINE, Google Scholar, Scopus, SAGE Research Methods, and ScienceDirect. Conclusion OSA leads to worsening of patients' personal relationships, decreasing work productivity, and increasing occupational accidents as well as MVAs. The costs of undiagnosed and untreated OSA to healthcare organizations are excessive. Thus, proper management of OSA will benefit not only the patient but will also provide widespread benefits to the society as a whole. FAU - Morsy, Nesreen E AU - Morsy NE AD - Department of Pulmonary Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. AD - Mansoura University Sleep Center, Mansoura, Egypt. FAU - Farrag, Nesrine S AU - Farrag NS AD - Public Health and Preventive Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. FAU - Zaki, Nevin F W AU - Zaki NFW AUID- ORCID: 0000-0001-5131-8228 AD - Assistant Professor of Psychiatry, Department of Psychiatry, Faculty of Medicine, Mansoura University, P.O. Box 36551, Gomhoria Street, Mansoura 35511, Egypt. AD - Mansoura University Sleep Center, Mansoura, Egypt, E-mail: nevinfzaki@yahoo.com. FAU - Badawy, Ahmad Y AU - Badawy AY AD - Department of Pulmonary Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. FAU - Abdelhafez, Sayed A AU - Abdelhafez SA AD - Department of Pulmonary Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. FAU - El-Gilany, Abdel-Hady AU - El-Gilany AH AD - Public Health and Preventive Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. FAU - El Shafey, Mohsen Mohammed AU - El Shafey MM AD - Department of Pulmonary Medicine, Faculty of Medicine, Mansoura University, Mansoura, Egypt. FAU - Pandi-Perumal, Seithikurippu R AU - Pandi-Perumal SR AD - Somnogen Canada Inc., Toronto, ON, Canada. FAU - Spence, David Warren AU - Spence DW AD - 652 Dufferin Street, Toronto, ON, Canada. FAU - BaHammam, Ahmed S AU - BaHammam AS AD - The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia. AD - Strategic Technologies Program of the National Plan for Sciences, Technology, and Innovation, Riyadh, Saudi Arabia. LA - eng PT - Journal Article PT - Review PL - Germany TA - Rev Environ Health JT - Reviews on environmental health JID - 0425754 SB - IM MH - Accidents, Occupational/statistics & numerical data MH - Accidents, Traffic/statistics & numerical data MH - Humans MH - Interpersonal Relations MH - Prevalence MH - Public Health/*statistics & numerical data MH - Sleep Apnea, Obstructive/economics/*epidemiology/etiology/*prevention & control OTO - NOTNLM OT - OSA OT - economic cost OT - legal OT - obstructive sleep apnea OT - road traffic accidents OT - society EDAT- 2019/05/16 06:00 MHDA- 2019/08/28 06:00 CRDT- 2019/05/16 06:00 PHST- 2018/11/05 00:00 [received] PHST- 2019/02/22 00:00 [accepted] PHST- 2019/05/16 06:00 [pubmed] PHST- 2019/08/28 06:00 [medline] PHST- 2019/05/16 06:00 [entrez] AID - reveh-2018-0068 [pii] AID - 10.1515/reveh-2018-0068 [doi] PST - ppublish SO - Rev Environ Health. 2019 Jun 26;34(2):153-169. doi: 10.1515/reveh-2018-0068.