PMID- 31089532
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 2508-7576 (Electronic)
IS  - 2508-6235 (Print)
IS  - 2508-6235 (Linking)
VI  - 26
IP  - 4
DP  - 2017 Dec 30
TI  - Circulating Monocyte Chemoattractant Protein-1 Levels and Lumbar Bone Mineral 
      Density in Korean Women.
PG  - 287-290
LID - 10.7570/jomes.2017.26.4.287 [doi]
AB  - BACKGROUND: Monocyte chemoattractant protein-1 (MCP-1) is expressed in adipose 
      tissue, macrophages, endothelial cells, and osteoblasts by parathyroid hormone 
      administration. Circulating MCP-1 levels are positively correlated with the 
      degree of obesity. However, whether circulating MCP-1 affects bone metabolism is 
      unclear. Therefore, in this study, the association between circulating MCP-1 
      levels and lumbar bone mineral density (BMD) based on menopausal status was 
      assessed. METHODS: We recruited 109 premenopausal and 46 postmenopausal Korean 
      women and examined the association between circulating MCP-1 concentrations and 
      various parameters including lumbar BMD based on menopausal status. RESULTS: A 
      significant increase in body weight, abdominal circumference, body mass index, 
      and MCP-1 levels (from 245.9+/-73.5 to 336.5+/-101.7 pg/mL) and significant decrease 
      (from 0.992+/-0.114 to 0.772+/-0.113 g/cm(2)) in lumbar BMD were observed after 
      menopause. However, circulating MCP-1 levels were not correlated with any 
      parameters including lumbar BMD in premenopausal or postmenopausal women. 
      CONCLUSION: Circulating MCP-1 levels were not correlated with lumbar BMD 
      regardless of menopausal status.
FAU - Lee, Seong-Kyu
AU  - Lee SK
AD  - Department of Biochemistry-Molecular Biology, Eulji University School of 
      Medicine, Daejeon; Department of Internal Medicine, Eulji University Hospital, 
      Daejeon, Korea.
LA  - eng
PT  - Journal Article
PL  - Korea (South)
TA  - J Obes Metab Syndr
JT  - Journal of obesity & metabolic syndrome
JID - 101704724
PMC - PMC6489469
OTO - NOTNLM
OT  - Bone density
OT  - Monocyte chemoattractant protein-1
OT  - Women
COIS- CONFLICTS OF INTEREST The author declares no conflict of interest.
EDAT- 2017/12/30 00:00
MHDA- 2017/12/30 00:01
PMCR- 2017/12/01
CRDT- 2019/05/16 06:00
PHST- 2017/11/11 00:00 [received]
PHST- 2017/11/20 00:00 [revised]
PHST- 2017/11/29 00:00 [accepted]
PHST- 2019/05/16 06:00 [entrez]
PHST- 2017/12/30 00:00 [pubmed]
PHST- 2017/12/30 00:01 [medline]
PHST- 2017/12/01 00:00 [pmc-release]
AID - jomes-26-287 [pii]
AID - 10.7570/jomes.2017.26.4.287 [doi]
PST - ppublish
SO  - J Obes Metab Syndr. 2017 Dec 30;26(4):287-290. doi: 10.7570/jomes.2017.26.4.287.