PMID- 31090288
OWN - NLM
STAT- MEDLINE
DCOM- 20190815
LR  - 20190815
IS  - 1001-5302 (Print)
IS  - 1001-5302 (Linking)
VI  - 44
IP  - 7
DP  - 2019 Apr
TI  - [Risk assessment of pesticide residues in domestic ginsengs].
PG  - 1327-1333
LID - 10.19540/j.cnki.cjcmm.20190319.102 [doi]
AB  - The study aims at taking risk assessment of pesticide residues in ginseng and 
      high risk pesticides were picked up in order to provide a scientific basis for 
      the establishment of maximum residue limits(MRLs) for pesticides in ginseng. 
      Residues of 246 pesticides in 80 ginseng samples collected from different place 
      were detected by GC-MS/MS and LC-MS/MS method. Acute and chronic intake risks 
      were evaluated by using deterministic approach, and the matrix ranking developed 
      by the Veterinary Residues Committee of the United Kingdom was referred to assess 
      risk score of pesticides. The 25 kinds of pesticide residues were detected in 
      ginseng samples, the detection rate of quintozene(PCNB) was 78%, which was the 
      most frequently detectable pesticide. The chronic dietary intake risks of 25 
      pesticide residues expressed as %ADI were 0.00%-2.6%, and their acute dietary 
      intake risks expressed as %ARfD were 0.00%-104.2%. Among them the acute dietary 
      intake risks of PCNB was 104%,which was the highest. The 25 pesticides were 
      divided into 3 groups by risk score, high risk group(4 pesticides), medium risk 
      group(6 pesticides), and low risk group(15 pesticides). Hexachlorobenzene, 
      phorate, PCNB and BHC were classified as high risk group. It is necessary and 
      effective to establish the limit of residual organic chlorine in ginseng from 
      Chinese Pharmacopoeia(2015 edition). MRLs for PCNB and hexachlorobenzene in 
      ginseng were proposed to be revised based on the results of risk assessment.
FAU - Wang, Ying
AU  - Wang Y
AD  - Intitute for Control of Chinese Traditional Medicine and Ethnic Medicine, 
      National Institutes for Food and Drug Control Beijing 100050, China.
FAU - Wang, Zhao
AU  - Wang Z
AD  - Intitute for Control of Chinese Traditional Medicine and Ethnic Medicine, 
      National Institutes for Food and Drug Control Beijing 100050, China.
FAU - Yue, Zhi-Hua
AU  - Yue ZH
AD  - Chinese Pharmacopoeia Commission Beijing 100061, China.
FAU - Jin, Hong-Yu
AU  - Jin HY
AD  - Intitute for Control of Chinese Traditional Medicine and Ethnic Medicine, 
      National Institutes for Food and Drug Control Beijing 100050, China.
FAU - Sun, Lei
AU  - Sun L
AD  - Intitute for Control of Chinese Traditional Medicine and Ethnic Medicine, 
      National Institutes for Food and Drug Control Beijing 100050, China.
FAU - Ma, Shuang-Cheng
AU  - Ma SC
AD  - Intitute for Control of Chinese Traditional Medicine and Ethnic Medicine, 
      National Institutes for Food and Drug Control Beijing 100050, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Zhongguo Zhong Yao Za Zhi
JT  - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese 
      materia medica
JID - 8913656
RN  - 0 (Drugs, Chinese Herbal)
RN  - 0 (Pesticide Residues)
MH  - Chromatography, Liquid
MH  - Drugs, Chinese Herbal/*standards
MH  - Panax/*chemistry
MH  - Pesticide Residues/*analysis
MH  - Risk Assessment
MH  - Tandem Mass Spectrometry
OTO - NOTNLM
OT  - deterministic approach
OT  - ginseng
OT  - pesticide residues
OT  - risk assessment
OT  - risk ranking
EDAT- 2019/05/16 06:00
MHDA- 2019/08/16 06:00
CRDT- 2019/05/16 06:00
PHST- 2019/05/16 06:00 [entrez]
PHST- 2019/05/16 06:00 [pubmed]
PHST- 2019/08/16 06:00 [medline]
AID - 10.19540/j.cnki.cjcmm.20190319.102 [doi]
PST - ppublish
SO  - Zhongguo Zhong Yao Za Zhi. 2019 Apr;44(7):1327-1333. doi: 
      10.19540/j.cnki.cjcmm.20190319.102.