PMID- 31111872
OWN - NLM
STAT- MEDLINE
DCOM- 20201201
LR  - 20201201
IS  - 1442-2050 (Electronic)
IS  - 1120-8694 (Linking)
VI  - 33
IP  - 2
DP  - 2020 Mar 5
TI  - Preoperative six-minute walk distance as a predictor of postoperative 
      complication in patients with esophageal cancer.
LID - doz050 [pii]
LID - 10.1093/dote/doz050 [doi]
AB  - Surgery for esophageal cancer is associated with high morbidity and mortality. 
      Reduced pulmonary functions and exercise capacity are known as risk factors for 
      complications after esophagectomy. The 6-minute walk distance (6MWD) measured by 
      the 6-minute walk test (6MWT) is a simple field test that can be used to evaluate 
      the functional exercise capacity of patients who undergo thoracic surgery. The 
      aim of this study was to evaluate the association of the preoperative 6MWD with 
      postoperative complications in patients with esophageal cancer. Records of a 
      total of 111 patients who underwent thoracic surgery followed by postoperative 
      rehabilitation from January 2013 to December 2015 were retrospectively reviewed. 
      Data of patients who experienced Clavien-Dindo grade II or severer (grade >/= II) 
      complications were compared with those who experienced grade </=I complications. 
      The 6MWD was significantly correlated with age, serum albumin concentration, 
      hemoglobin concentration, and hand grip strength. A total of 42 patients 
      experienced grade >/=II. The 6MWD of patients with grade >/= II complications was 
      significantly shorter than that of those with grade </=I complications. In receiver 
      operating characteristic analysis, 6MWD </= 454 m was a threshold for predicting 
      grade >/=II complications with 71.0% sensitivity and 54.8% specificity. The 
      incidence of grade >/=II complications led to delayed ambulation and longer stays 
      in hospital. In the multiple regression analysis, the preoperative risk factors 
      for incidence of grade >/=II complications included lower levels of preoperative 
      6MWD and % of the predicted value of forced expiratory volume in 1 second. Our 
      results indicate that the 6MWT is useful to assess preoperative physical status 
      in patients with esophageal cancer.
CI  - (c) The Author(s) 2019. Published by Oxford University Press on behalf of 
      International Society for Diseases of the Esophagus. All rights reserved. For 
      permissions, please e-mail: journals.permissions@oup.com.
FAU - Inoue, Takayuki
AU  - Inoue T
AD  - Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya.
FAU - Ito, Satoru
AU  - Ito S
AD  - Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya.
AD  - Department of Respiratory Medicine, Nagoya University Graduate School of 
      Medicine, Nagoya.
AD  - Department of Respiratory Medicine and Allergology, Aichi Medical University, 
      Nagakute, Japan.
FAU - Kanda, Mitsuro
AU  - Kanda M
AD  - Department of Gastroenterological Surgery II, Nagoya University Graduate School 
      of Medicine, Nagoya.
FAU - Niwa, Yukiko
AU  - Niwa Y
AD  - Department of Gastroenterological Surgery II, Nagoya University Graduate School 
      of Medicine, Nagoya.
FAU - Nagaya, Motoki
AU  - Nagaya M
AD  - Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya.
FAU - Nishida, Yoshihiro
AU  - Nishida Y
AD  - Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya.
FAU - Hasegawa, Yoshinori
AU  - Hasegawa Y
AD  - Department of Respiratory Medicine, Nagoya University Graduate School of 
      Medicine, Nagoya.
FAU - Koike, Masahiko
AU  - Koike M
AD  - Department of Gastroenterological Surgery II, Nagoya University Graduate School 
      of Medicine, Nagoya.
FAU - Kodera, Yasuhiro
AU  - Kodera Y
AD  - Department of Gastroenterological Surgery II, Nagoya University Graduate School 
      of Medicine, Nagoya.
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
PL  - United States
TA  - Dis Esophagus
JT  - Diseases of the esophagus : official journal of the International Society for 
      Diseases of the Esophagus
JID - 8809160
SB  - IM
MH  - Aged
MH  - Carcinoma/physiopathology/*surgery
MH  - Esophageal Neoplasms/physiopathology/*surgery
MH  - *Esophagectomy
MH  - Female
MH  - Health Status Indicators
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - *Physical Fitness
MH  - Postoperative Complications/diagnosis/epidemiology/*etiology
MH  - *Preoperative Care
MH  - Retrospective Studies
MH  - Risk Factors
MH  - Sensitivity and Specificity
MH  - *Walk Test
OTO - NOTNLM
OT  - complications
OT  - esophageal cancer surgery
OT  - rehabilitation
OT  - surgery
EDAT- 2019/05/22 06:00
MHDA- 2020/12/02 06:00
CRDT- 2019/05/22 06:00
PHST- 2019/04/26 00:00 [accepted]
PHST- 2019/01/24 00:00 [received]
PHST- 2019/03/22 00:00 [revised]
PHST- 2019/05/22 06:00 [pubmed]
PHST- 2020/12/02 06:00 [medline]
PHST- 2019/05/22 06:00 [entrez]
AID - 5492604 [pii]
AID - 10.1093/dote/doz050 [doi]
PST - ppublish
SO  - Dis Esophagus. 2020 Mar 5;33(2):doz050. doi: 10.1093/dote/doz050.