PMID- 31116085
OWN - NLM
STAT- MEDLINE
DCOM- 20210809
LR  - 20210809
IS  - 1464-0694 (Electronic)
IS  - 0960-2011 (Linking)
VI  - 30
IP  - 10
DP  - 2020 Dec
TI  - Long-term cognitive disability after traumatic brain injury: Contribution of the 
      DEX relative questionnaires.
PG  - 1905-1924
LID - 10.1080/09602011.2019.1618345 [doi]
AB  - Executive functions are high-level cognitive processes commonly impaired after 
      severe traumatic brain injury (sTBI), which may be associated with persistent 
      anosognosia. The dysexecutive questionnaire (DEX) was designed to assess 
      different domains of executive functioning in daily life. Two versions of the DEX 
      exist (DEX-S completed by the patient, DEX-O completed by a relative) to compare 
      cognitive complaints and patient's awareness. This work was aimed at studying the 
      relevance of DEX-O for assessing daily-life limitations, the persistence of 
      anosognosia and its association with global disability (GOSE) and magnetic 
      resonance imaging (MRI) markers of brain alterations. Sixty-three patients (and 
      relatives) were included within 63.4 months (+/-20.7) after sTBI. DEX-S and DEX-O 
      scores were significantly positively correlated. We obtained significant 
      correlations between DEX-S and episodic memory and phasic alert but not with 
      executive assessment, GOSE and diffusion MRI markers. DEX-O was significantly 
      correlated with executive function, episodic memory, attention (phasic alert 
      sustained and divided attention), with the GOSE and the volume of the body of the 
      corpus callosum (MRI marker). Anosognosia score (DEX-O minus DEX-S) correlated 
      with mean diffusivity measure. These results highlight the clinical interest of 
      DEX-O in assessing long-term disability.
FAU - Lesimple, Blandine
AU  - Lesimple B
AD  - AP-HP, Service de Neuroreanimation chirurgicale, Hopital Pitie-Salpetriere, 
      Paris, France.
AD  - SAMSAH La Note Bleue, Fondation Partage et Vie, Paris, France.
FAU - Caron, Elsa
AU  - Caron E
AD  - AP-HP, Service de Medecine Physique et Readaptation, Hopital Pitie-Salpetriere, 
      Paris, France.
AD  - dSAMSAH -SAVS, Association Guyanaise contre les Maladies Neuromusculaires, 
      Cayenne, France.
FAU - Lefort, Muriel
AU  - Lefort M
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
FAU - Debarle, Clara
AU  - Debarle C
AD  - GRC-Sorbonne Universite n degrees 18 HanCRe, Sorbonne Universite, Paris, France.
FAU - Pelegrini-Issac, Melanie
AU  - Pelegrini-Issac M
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
FAU - Cassereau, Didier
AU  - Cassereau D
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
AD  - ESPCI ParisTech, PSL Research University, Paris, France.
FAU - Delphine, Sebastien
AU  - Delphine S
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
AD  - Institut des Neurosciences Translationnelles de Paris, IHU-A-ICM, Institut du 
      Cerveau et de la Moelle epiniere, Paris, France.
FAU - Torkomian, Gregory
AU  - Torkomian G
AD  - AP-HP, Service de Neuroreanimation chirurgicale, Hopital Pitie-Salpetriere, 
      Paris, France.
FAU - Battisti, Valentine
AU  - Battisti V
AD  - AP-HP, Service de Neuroreanimation chirurgicale, Hopital Pitie-Salpetriere, 
      Paris, France.
FAU - Bossale, Pierrette
AU  - Bossale P
AD  - AP-HP, Service de Neuroreanimation chirurgicale, Hopital Pitie-Salpetriere, 
      Paris, France.
FAU - Galanaud, Damien
AU  - Galanaud D
AUID- ORCID: 0000-0002-9285-8121
AD  - AP-HP, Service de Neuroradiologie, Hopital Pitie-Salpetriere, Paris, France.
FAU - Puybasset, Louis
AU  - Puybasset L
AD  - AP-HP, Service de Neuroreanimation chirurgicale, Hopital Pitie-Salpetriere, 
      Paris, France.
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
FAU - Pradat-Diehl, Pascale
AU  - Pradat-Diehl P
AD  - AP-HP, Service de Medecine Physique et Readaptation, Hopital Pitie-Salpetriere, 
      Paris, France.
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
AD  - GRC-Sorbonne Universite n degrees 18 HanCRe, Sorbonne Universite, Paris, France.
FAU - Perlbarg, Vincent
AU  - Perlbarg V
AD  - Sorbonne Universite, CNRS, INSERM, Laboratoire d'Imagerie Biomedicale, LIB, 
      Paris, France.
AD  - Bioinformatics and Biostatistics Core Facility, iCONICS, ICM, Institut du Cerveau 
      et de la Moelle epiniere, Paris, France.
LA  - eng
PT  - Journal Article
DEP - 20190522
PL  - England
TA  - Neuropsychol Rehabil
JT  - Neuropsychological rehabilitation
JID - 9112672
SB  - IM
MH  - Adult
MH  - Agnosia/*diagnosis/etiology/pathology/physiopathology
MH  - Attention/physiology
MH  - Brain Injuries, Traumatic/complications/*diagnosis/pathology/physiopathology
MH  - Cognitive Dysfunction/*diagnosis/etiology/pathology/physiopathology
MH  - Corpus Callosum/diagnostic imaging/*pathology
MH  - *Executive Function/physiology
MH  - Female
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Male
MH  - Memory, Episodic
MH  - Middle Aged
MH  - *Neuropsychological Tests/standards
MH  - Psychometrics
MH  - Surveys and Questionnaires
OTO - NOTNLM
OT  - Anosognosia
OT  - Dysexecutive questionnaire
OT  - Executive functions
OT  - Magnetic resonance imaging
OT  - Traumatic brain injury
EDAT- 2019/05/23 06:00
MHDA- 2021/08/10 06:00
CRDT- 2019/05/23 06:00
PHST- 2019/05/23 06:00 [pubmed]
PHST- 2021/08/10 06:00 [medline]
PHST- 2019/05/23 06:00 [entrez]
AID - 10.1080/09602011.2019.1618345 [doi]
PST - ppublish
SO  - Neuropsychol Rehabil. 2020 Dec;30(10):1905-1924. doi: 
      10.1080/09602011.2019.1618345. Epub 2019 May 22.