PMID- 31118646 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20201001 IS - 1176-6328 (Print) IS - 1178-2021 (Electronic) IS - 1176-6328 (Linking) VI - 15 DP - 2019 TI - Personality associated with depressive status in individuals with type 2 diabetes mellitus. PG - 1133-1139 LID - 10.2147/NDT.S200012 [doi] AB - Objective: Type 2 diabetes mellitus (T2DM) is associated with a high prevalence of depression, and depression is influenced by personality traits; however, these psychological factors have not been well studied in individuals with T2DM. The association between the use of a 5-factor model of personality and depressive symptoms was examined in individuals with T2DM. Methods: The subjects were 435 T2DM patients (mean age 63.1+/-12.6 years). Depressive status and personality traits were assessed using the Center for Epidemiologic Studies Depression Scale and the Ten-Item Personality Inventory, Japanese version, respectively. Lifestyle factors and glycated hemoglobin A1c levels in the patients were also included in the analyses. Results: Among the 435 subjects with T2DM, 130 (29.9%) exhibited possible depression, and 68 (15.6%) exhibited probable depression. After adjustment for confounders, Extraversion, Agreeableness and Neuroticism were found to be significantly associated with the presence of depression. No relationships were found between depression and HbA1c. Conclusion: These findings indicate that Extraversion and Agreeableness are protective factors, and Neuroticism is a risk factor for depression in T2DM patients. Psychological therapy focusing on personality may reduce depressive symptoms. Additional studies are needed to examine the relationships between psychological factors and depressive symptoms using a longitudinal study design. FAU - Yasui-Furukori, Norio AU - Yasui-Furukori N AD - Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan. AD - Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Murakami, Hiroshi AU - Murakami H AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Otaka, Hideyuki AU - Otaka H AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Nakayama, Hirofumi AU - Nakayama H AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Murabayashi, Masaya AU - Murabayashi M AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Mizushiri, Satoru AU - Mizushiri S AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Matsumura, Koki AU - Matsumura K AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Tanabe, Jutaro AU - Tanabe J AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Matsuhashi, Yuki AU - Matsuhashi Y AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Yanagimachi, Miyuki AU - Yanagimachi M AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Nakamura, Kazuhiko AU - Nakamura K AD - Department of Neuropsychiatry, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Daimon, Makoto AU - Daimon M AD - Department of Endocrinology and Metabolism, Hirosaki University Graduate School of Medicine, Hirosaki, Japan. FAU - Sugawara, Norio AU - Sugawara N AD - Department of Psychiatry, Dokkyo Medical University School of Medicine, Tochigi, Japan. AD - Department of Clinical Epidemiology, Translational Medical Center, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan. LA - eng PT - Journal Article DEP - 20190503 PL - New Zealand TA - Neuropsychiatr Dis Treat JT - Neuropsychiatric disease and treatment JID - 101240304 PMC - PMC6504551 OTO - NOTNLM OT - Japanese OT - cross-sectional studies OT - depressive symptoms OT - personality OT - type 2 diabetes COIS- Norio Yasui-Furukori has been a speaker for Dainippon-Sumitomo Pharmaceutical, Mochida Pharmaceutical, MSD and Otsuka Pharmaceutical. The authors report no other conflicts of interest in this work. EDAT- 2019/05/24 06:00 MHDA- 2019/05/24 06:01 PMCR- 2019/05/03 CRDT- 2019/05/24 06:00 PHST- 2018/12/31 00:00 [received] PHST- 2019/04/01 00:00 [accepted] PHST- 2019/05/24 06:00 [entrez] PHST- 2019/05/24 06:00 [pubmed] PHST- 2019/05/24 06:01 [medline] PHST- 2019/05/03 00:00 [pmc-release] AID - 200012 [pii] AID - 10.2147/NDT.S200012 [doi] PST - epublish SO - Neuropsychiatr Dis Treat. 2019 May 3;15:1133-1139. doi: 10.2147/NDT.S200012. eCollection 2019.