PMID- 31126813 OWN - NLM STAT- MEDLINE DCOM- 20200914 LR - 20200914 IS - 1531-6564 (Electronic) IS - 0363-5023 (Linking) VI - 44 IP - 8 DP - 2019 Aug TI - Minimal Clinically Important Differences for PROMIS Physical Function, Upper Extremity, and Pain Interference in Carpal Tunnel Release Using Region- and Condition-Specific PROM Tools. PG - 635-640 LID - S0363-5023(18)31334-0 [pii] LID - 10.1016/j.jhsa.2019.04.004 [doi] AB - PURPOSE: Uncertainty exists about what change in Patient-Reported Outcomes Measurement Information System (PROMIS) scores represents a clinically relevant improvement (minimal clinically important difference [MCID]) in hand surgery care. Using a region-specific patient-reported outcome measure (PROM) (Michigan Hand Question [MHQ]) and a condition-specific PROM (Boston Carpal Tunnel Questionnaire [BCTQ]), MCID values were determined for PROMIS Physical Function (PF), Upper Extremity (UE), and Pain Interference (PI) computerized adaptive testing among patients undergoing carpal tunnel release (CTR). METHODS: Patients undergoing CTR with a single surgeon from November 2014 to April 2017 were asked to complete the BCTQ, MHQ, and PROMIS PF, UE, and PI at each visit. Patients who had completed questionnaires both at a preoperative and either a 6-week or a 3-month postoperative visit were included. The PROMIS PF, UE, and PI MCID values were calculated using previously determined MCID estimates in the literature with both region- (ie, MHQ) and condition-specific (ie, BCTQ) PROM anchors. The PROMIS domain MCID estimates were also determined using the distribution-based method. RESULTS: A total of 70 patients fit our inclusion criteria. Using MHQ Function and Pain, PROMIS UE, PF, and PI MCIDs were 6.3, 1.8, and -8.9, respectively. Using the average of the 2 BCTQ domains, PROMIS UE, PF, and PI MCIDs were 8.0, 2.8, and -9.7, respectively. Using the distribution-based method, PROMIS UE, PF, and PI MCIDs were 4.2, 2.7, and -4.1, respectively. CONCLUSIONS: Using region- and condition-specific PROMs, we were able to provide MCID estimates of PROMIS UE, PF, and PI for patients undergoing CTR. CLINICAL RELEVANCE: Estimating PROMIS UE, PF, and PI MCIDs in CTR using validated region- and condition-specific PROMs provides hand surgeons a way to evaluate CTR outcomes not previously described in the literature. Surgeons should understand that these values are only estimates and future work is needed to verify whether they reflect clinical improvement. CI - Copyright (c) 2019 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved. FAU - Bernstein, David N AU - Bernstein DN AD - University of Rochester School of Medicine and Dentistry, Rochester, NY. FAU - Houck, Jeff R AU - Houck JR AD - George Fox University, Newberg, OR. FAU - Mahmood, Bilal AU - Mahmood B AD - Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, NY. FAU - Hammert, Warren C AU - Hammert WC AD - Department of Orthopaedics and Rehabilitation, University of Rochester Medical Center, Rochester, NY. Electronic address: Warren_Hammert@urmc.rochester.edu. LA - eng PT - Journal Article DEP - 20190522 PL - United States TA - J Hand Surg Am JT - The Journal of hand surgery JID - 7609631 SB - IM CIN - J Hand Surg Am. 2019 Dec;44(12):e1. PMID: 31806121 CIN - J Hand Surg Am. 2019 Dec;44(12):e7. PMID: 31806124 MH - Carpal Tunnel Syndrome/*physiopathology/*surgery MH - Female MH - Humans MH - Male MH - Middle Aged MH - Minimal Clinically Important Difference MH - Pain Management MH - Pain Measurement MH - *Patient Reported Outcome Measures MH - Prospective Studies MH - Recovery of Function MH - Surveys and Questionnaires OTO - NOTNLM OT - Carpal tunnel release OT - MCID OT - PROMIS OT - carpal tunnel syndrome OT - minimal clinically important difference OT - patient-reported outcomes OT - value-based health care EDAT- 2019/05/28 06:00 MHDA- 2020/09/15 06:00 CRDT- 2019/05/26 06:00 PHST- 2018/09/04 00:00 [received] PHST- 2019/02/10 00:00 [revised] PHST- 2019/04/18 00:00 [accepted] PHST- 2019/05/28 06:00 [pubmed] PHST- 2020/09/15 06:00 [medline] PHST- 2019/05/26 06:00 [entrez] AID - S0363-5023(18)31334-0 [pii] AID - 10.1016/j.jhsa.2019.04.004 [doi] PST - ppublish SO - J Hand Surg Am. 2019 Aug;44(8):635-640. doi: 10.1016/j.jhsa.2019.04.004. Epub 2019 May 22.