PMID- 31128138
OWN - NLM
STAT- MEDLINE
DCOM- 20190621
LR  - 20221207
IS  - 1879-0631 (Electronic)
IS  - 0024-3205 (Linking)
VI  - 230
DP  - 2019 Aug 1
TI  - Type 2 diabetes mellitus reduces clinical complications and mortality in Stanford 
      type B aortic dissection after thoracic endovascular aortic repair: A 3-year 
      follow-up study.
PG  - 104-110
LID - S0024-3205(19)30411-4 [pii]
LID - 10.1016/j.lfs.2019.05.055 [doi]
AB  - BACKGROUND: Previous studies have demonstrated that type 2 diabetes mellitus 
      (T2DM) is negatively correlated with the occurrence of aortic dissection (AD). 
      This study aimed to investigate the effects of T2DM on the prognosis of Stanford 
      type B AD (STBAD) patients after thoracic endovascular aortic repair (TEVAR). 
      METHODS: STBAD patients (n = 141) who underwent TEVAR received an oral glucose 
      tolerance test (OGTT) and were divided into a normal glucose (NG, n = 55) group, 
      an abnormal glucose tolerance (AGT, n = 48) group and a T2DM (n = 38) group 
      according to the results of the OGTT. Data on mortality, clinical complications, 
      left ventricular (LV) remodeling and aortic remodeling were collected during the 
      3-year follow-up. RESULTS: Lower mortality and fewer clinical complications after 
      TEVAR were found in the T2DM group than in the NG group. Multivariate linear 
      regression analysis showed that 2-hour postprandial glucose (Glu-2h) was 
      negatively correlated with mortality and the occurrence of clinical complications 
      in STBAD patients after TEVAR. In addition, better LV remodeling, larger true 
      lumen areas and smaller false lumen areas in both the proximal aortas and 
      abdominal aortas were observed in the T2DM group than in the NG group. 
      Furthermore, no significant differences in mortality or clinical complications 
      after TEVAR were found between the NG group and the AGT group or between the T2DM 
      group and the AGT group. CONCLUSION: During the 3-year follow-up period, 
      mortality and clinical complications in STBAD patients after TEVAR were 
      significantly reduced in the T2DM group. For STBAD patients who undergo TEVAR, 
      properly relaxing of blood glucose control requirements may be beneficial for 
      their prognosis.
CI  - Copyright (c) 2019. Published by Elsevier Inc.
FAU - Liu, Hongtao
AU  - Liu H
AD  - Department of Cardiovascular Medicine, Shenzhen Longhua District Central 
      Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, 
      Shenzhen, Guangdong Province 518110, China.
FAU - Shi, Lei
AU  - Shi L
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China.
FAU - Zeng, Tao
AU  - Zeng T
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China.
FAU - Ji, Qingwei
AU  - Ji Q
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China; Emergency & Critical Care Center, Beijing Anzhen 
      Hospital, Capital Medical University and Beijing Institute of Heart, Lung, and 
      Blood Vessel Diseases, Beijing 100029, China.
FAU - Shi, Ying
AU  - Shi Y
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China.
FAU - Huang, Ying
AU  - Huang Y
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China.
FAU - Zhang, Le
AU  - Zhang L
AD  - Department of Cardiovascular Medicine, Shenzhen Longhua District Central 
      Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, 
      Shenzhen, Guangdong Province 518110, China.
FAU - Xiao, Ting
AU  - Xiao T
AD  - Department of Cardiovascular Medicine, Shenzhen Longhua District Central 
      Hospital, Longhua Central Hospital Affiliated Guangdong Medical University, 
      Shenzhen, Guangdong Province 518110, China.
FAU - Ye, Jing
AU  - Ye J
AD  - Department of Cardiology, Renmin Hospital of Wuhan University; Cardiovascular 
      Research Institute, Wuhan University; Hubei Key Laboratory of Cardiology, Wuhan 
      430060, China.
FAU - Lin, Yingzhong
AU  - Lin Y
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China. Electronic address: yingzhonglin@126.com.
FAU - Liu, Ling
AU  - Liu L
AD  - Department of Cardiology, The People's Hospital of Guangxi Zhuang Autonomous 
      Region, Nanning 530021, China. Electronic address: gxliu@126.com.
LA  - eng
PT  - Journal Article
DEP - 20190522
PL  - Netherlands
TA  - Life Sci
JT  - Life sciences
JID - 0375521
RN  - IY9XDZ35W2 (Glucose)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aortic Dissection/mortality/*physiopathology/surgery
MH  - Aorta, Abdominal/physiopathology
MH  - Aorta, Thoracic/physiopathology/*surgery
MH  - Diabetes Mellitus, Type 2/physiopathology
MH  - Female
MH  - Follow-Up Studies
MH  - Glucose/metabolism
MH  - Glucose Tolerance Test
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Time Factors
MH  - Tomography, X-Ray Computed
MH  - Treatment Outcome
MH  - Vascular Remodeling
OTO - NOTNLM
OT  - Aortic remodeling
OT  - Clinical complications
OT  - Mortality
OT  - Stanford type B aortic dissection
OT  - Thoracic endovascular aortic repair
OT  - Type 2 diabetes mellitus
EDAT- 2019/05/28 06:00
MHDA- 2019/06/22 06:00
CRDT- 2019/05/26 06:00
PHST- 2019/01/09 00:00 [received]
PHST- 2019/05/12 00:00 [revised]
PHST- 2019/05/21 00:00 [accepted]
PHST- 2019/05/28 06:00 [pubmed]
PHST- 2019/06/22 06:00 [medline]
PHST- 2019/05/26 06:00 [entrez]
AID - S0024-3205(19)30411-4 [pii]
AID - 10.1016/j.lfs.2019.05.055 [doi]
PST - ppublish
SO  - Life Sci. 2019 Aug 1;230:104-110. doi: 10.1016/j.lfs.2019.05.055. Epub 2019 May 
      22.