PMID- 31129935
OWN - NLM
STAT- MEDLINE
DCOM- 20200616
LR  - 20200616
IS  - 2208-7958 (Electronic)
VI  - 48
IP  - 5
DP  - 2019 May
TI  - Hyperglycaemic presentations in type 2 diabetes.
PG  - 263-267
LID - 10.31128/AJGP-12-18-4785 [doi]
AB  - BACKGROUND: Hyperosmolar hyperglycaemic state (HHS) is a syndrome that occurs in 
      patients with type 2 diabetes mellitus (T2DM) and is comparable to diabetic 
      ketoacidosis (DKA) seen in patients with type 1 diabetes. For a general 
      practitioner working in a rural emergency department, recognition of HHS in a 
      patient presenting with the triad of severe dehydration, hyperglycaemia and 
      hyperosmolality is important to guide management and plan for disposition. 
      OBJECTIVES: This article reviews the hyperglycaemic states that can occur in 
      patients with T2DM. The reasons for the biochemical derangements in both HHS and 
      DKA are outlined, with a focus on the recognition and management of HHS. 
      DISCUSSION: Knowledge of the pathophysiology that influences HHS helps understand 
      of its clinical presentation and treatment. HHS has a high mortality rate 
      (5-20%), and having access to clinical guidelines from a referring hospital is 
      useful to guide early management strategies.
FAU - Willix, Clare
AU  - Willix C
AD  - MBBS, FRACGP, FACRRM, Clinical Senior Lecturer, Rural Clinical School of Western 
      Australia, Bunbury, WA. clare.willix@rcswa.edu.au
FAU - Griffiths, Emma
AU  - Griffiths E
AD  - MBBS, MPHTM, FRACGP, FARGP, FAFPHM, Clinical Senior Lecturer, Rural Clinical 
      School of Western Australia, Broome, WA
FAU - Singleton, Sally
AU  - Singleton S
AD  - MBBS, BMedSc, MPHTM, FAFPHM, FRACGP, FACRRM, Clinical Senior Lecturer, Rural 
      Clinical School of Western Australia, Broome, WA
LA  - eng
PT  - Journal Article
PL  - Australia
TA  - Aust J Gen Pract
JT  - Australian journal of general practice
JID - 101718099
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Blood Glucose/analysis
MH  - Diabetes Mellitus, Type 2/blood/*complications/physiopathology
MH  - Diabetic Ketoacidosis/blood/etiology/physiopathology
MH  - Humans
MH  - Hyperglycemia/blood/*etiology/physiopathology
MH  - Hyperglycemic Hyperosmolar Nonketotic Coma/blood/etiology/physiopathology
MH  - Male
MH  - Middle Aged
EDAT- 2019/05/28 06:00
MHDA- 2020/06/17 06:00
CRDT- 2019/05/28 06:00
PHST- 2019/05/28 06:00 [entrez]
PHST- 2019/05/28 06:00 [pubmed]
PHST- 2020/06/17 06:00 [medline]
AID - 10.31128/AJGP-12-18-4785 [doi]
PST - ppublish
SO  - Aust J Gen Pract. 2019 May;48(5):263-267. doi: 10.31128/AJGP-12-18-4785.