PMID- 31131214
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231011
IS  - 2211-4599 (Print)
IS  - 2211-4599 (Electronic)
IS  - 2211-4599 (Linking)
VI  - 13
IP  - 2
DP  - 2019 Apr
TI  - The Assessment of Clinically Significant Differences in Treating Spinal Deformity 
      Using the SRS Questionnaire: What Is the Threshold of Change That Is Meaningful 
      to Patients?
PG  - 153-157
LID - 10.14444/6020 [doi]
AB  - BACKGROUND: The measurement of health-related quality of life is important in 
      spinal deformity surgery. The Scoliosis Research Society questionnaire has 
      allowed disease-specific research in this area, and determining the minimal 
      clinically important difference (MCID) is as important as it is elusive. We seek 
      to further refine our estimations of clinically perceived improvements by the 
      patient. METHODS: We used an anchor-based approach for each domain of the SRS 
      questionnaire to compare changes at 1 year after treatment. We set the MCID as 
      the upper 95% boundary of the "no change" group bordering the "improvement" arm, 
      where the patients may start to perceive their own change toward the better. We 
      compared this with the mean change. RESULTS: The threshold value for the MCID was 
      0.54 for the pain domain, 0.31 for function, 0.62 for self-image, and 0.5 for 
      mental health. The mean changes in our group's pain and self-image exceeded their 
      MCID. CONCLUSIONS: Compared with our previous work, we further attempted to 
      refine our assessment of the MCID in spinal deformity. Pain continues to show 
      clinically significant improvement, and self-image also demonstrated mean 
      improvement over its estimated MCID. LEVEL OF EVIDENCE: 2. CLINICAL RELEVANCE: 
      This result in self-image is an important addition to the MCID literature, given 
      its lack of consistency in previous work.
FAU - Berven, Sigurd
AU  - Berven S
AD  - University of California, San Francisco, San Francisco, California.
FAU - Baron, Matthew
AU  - Baron M
AD  - University of Washington School of Medicine, Seattle, Washington.
FAU - Deviren, Vedat
AU  - Deviren V
AD  - University of California, San Francisco, San Francisco, California.
FAU - Glassman, Steven
AU  - Glassman S
AD  - Norton Leatherman Spine Center, Louisville, Kentucky.
FAU - Bridwell, Keith
AU  - Bridwell K
AD  - Washington University, St Louis, Missouri.
FAU - Verma, Kushagra
AU  - Verma K
AD  - University of Washington School of Medicine, Seattle, Washington.
LA  - eng
PT  - Journal Article
DEP - 20190430
PL  - Netherlands
TA  - Int J Spine Surg
JT  - International journal of spine surgery
JID - 101579005
PMC - PMC6510187
OTO - NOTNLM
OT  - MCID
OT  - SRS-22R
OT  - adult deformity
OT  - outcomes
COIS- Disclosures and COI: The authors received no funding for this study and report no 
      conflicts of interest. The Institutional Review Board was through the Spinal 
      Deformity Study Group and each center: University of California San Francisco, 
      Norton Leatherman Spine Center, Washington University
EDAT- 2019/05/28 06:00
MHDA- 2019/05/28 06:01
PMCR- 2019/04/30
CRDT- 2019/05/28 06:00
PHST- 2019/05/28 06:00 [entrez]
PHST- 2019/05/28 06:00 [pubmed]
PHST- 2019/05/28 06:01 [medline]
PHST- 2019/04/30 00:00 [pmc-release]
AID - 10.14444/6020 [doi]
PST - epublish
SO  - Int J Spine Surg. 2019 Apr 30;13(2):153-157. doi: 10.14444/6020. eCollection 2019 
      Apr.