PMID- 31132863
OWN - NLM
STAT- MEDLINE
DCOM- 20200224
LR  - 20200224
IS  - 1465-3338 (Electronic)
IS  - 0307-9457 (Linking)
VI  - 48
IP  - sup1
DP  - 2019 Sep
TI  - The residue levels of spinosad and abamectin in eggs and tissues of laying hens 
      following spray application.
PG  - S44-S51
LID - 10.1080/03079457.2019.1623380 [doi]
AB  - Spinosad (SPN) and abamectin (ABM) are used in poultry premises to control 
      external parasites including red mites (Dermanyssus gallinae). This study aimed 
      to determine levels of SPN (spinosyn A + spinosyn D) and ABM residues in egg and 
      edible tissues of laying hens following spray application. A total of 36 laying 
      hens were divided into four groups of nine birds each, and they were kept in 
      individual cages. Two different concentrations of SPN (2 and 4 g/l) and ABM 
      (0.025 and 0.033 g/l) were applied in stocked and empty cages, respectively. Eggs 
      were collected individually for 30 days. All hens were sacrificed at day 30 
      post-treatment, and tissue samples (liver, breast muscle, fat and skin) were 
      collected. The residue levels in eggs and tissues were determined by high 
      pressure liquid chromatography. ABM residues were not detectable in egg samples. 
      SPN residues in eggs and residues of both ABM and SPN in liver, muscle and fat 
      were under the maximum residue limits (MRLs) following low and high concentration 
      applications. However, although the MRLs have not been established for SPN and 
      ABM in skin tissue of chicken, residues in the skin detected at the low and high 
      concentrations were greater than the MRLs for other edible tissues (except fat 
      tissue) indicating that a withdrawal period would be necessary for the skin 
      tissue after ABM and SPN use in laying hens.
FAU - Gokbulut, Cengiz
AU  - Gokbulut C
AUID- ORCID: 0000-0002-4912-7307
AD  - Department of Pharmacology, Faculty of Medicine, Balikesir University , Balikesir 
      , Turkey.
FAU - Ozuicli, Mehmet
AU  - Ozuicli M
AD  - Department of Parasitology, Faculty of Veterinary Medicine, Bursa Uludag 
      University , Bursa , Turkey.
FAU - Aslan, Busra
AU  - Aslan B
AD  - Department of Veterinary Pharmacology and Toxicology, Institute of Health 
      Science, Balikesir University , Balikesir , Turkey.
FAU - Aydin, Levent
AU  - Aydin L
AD  - Department of Parasitology, Faculty of Veterinary Medicine, Bursa Uludag 
      University , Bursa , Turkey.
FAU - Cirak, Veli Yilgor
AU  - Cirak VY
AUID- ORCID: 0000-0003-0570-2514
AD  - Department of Parasitology, Faculty of Veterinary Medicine, Bursa Uludag 
      University , Bursa , Turkey.
LA  - eng
PT  - Journal Article
DEP - 20190702
PL  - England
TA  - Avian Pathol
JT  - Avian pathology : journal of the W.V.P.A
JID - 8210638
RN  - 0 (Drug Combinations)
RN  - 0 (Macrolides)
RN  - 0 (spinosyn D)
RN  - 5U8924T11H (abamectin)
RN  - 70288-86-7 (Ivermectin)
RN  - XPA88EAP6V (spinosad)
SB  - IM
MH  - Animals
MH  - Chickens/*parasitology
MH  - Drug Combinations
MH  - Female
MH  - Ivermectin/*analogs & derivatives/analysis
MH  - Macrolides/*analysis
MH  - Mite Infestations/drug therapy/parasitology/*veterinary
MH  - Mites/*physiology
MH  - Ovum/parasitology
MH  - Poultry Diseases/*drug therapy/parasitology
OTO - NOTNLM
OT  - Poultry
OT  - acaricides
OT  - consumer health
OT  - residue
OT  - withdrawal period
EDAT- 2019/05/28 06:00
MHDA- 2020/02/25 06:00
CRDT- 2019/05/29 06:00
PHST- 2019/05/28 06:00 [pubmed]
PHST- 2020/02/25 06:00 [medline]
PHST- 2019/05/29 06:00 [entrez]
AID - 10.1080/03079457.2019.1623380 [doi]
PST - ppublish
SO  - Avian Pathol. 2019 Sep;48(sup1):S44-S51. doi: 10.1080/03079457.2019.1623380. Epub 
      2019 Jul 2.