PMID- 31135630
OWN - NLM
STAT- MEDLINE
DCOM- 20210428
LR  - 20221005
IS  - 1539-2031 (Electronic)
IS  - 0192-0790 (Print)
IS  - 0192-0790 (Linking)
VI  - 54
IP  - 1
DP  - 2020 Jan
TI  - Epidemiology and Diagnosis of Gastroparesis in the United States: A 
      Population-based Study.
PG  - 50-54
LID - 10.1097/MCG.0000000000001231 [doi]
AB  - GOALS: We aimed to establish the epidemiological characteristics and 
      documentation of diagnostic workup for gastroparesis (GP). BACKGROUND: No study 
      has used a national database to evaluate the prevalence, demographics, and 
      associated comorbid conditions of GP, and document rates of proper diagnosis. 
      MATERIALS AND METHODS: This was a cross-sectional population-based study using 
      the Explorys Platform to determine the prevalence of GP in a large and diverse 
      population highly representative of the US population and to examine the 
      diagnostic approach of GP. Data collected were individual characteristics from 
      electronic medical records (EMRs) included age, ethnicity/race, sex, diagnostic 
      report for esophagogastroduodenoscopy (EGD) and gastric emptying study (GES). 
      RESULTS: A total of 43,827,910 medical records were surveyed (1999 to 2014), of 
      which 69,950 had a diagnosis of GP, yielding an overall prevalence of 0.16%. We 
      identified 249,930 EMRs with type 1 diabetes mellitus (T1DM), and 2,940,280 EMR's 
      with type 2 diabetes mellitus (T2DM), of which 11,470 (4.59%) and 38,670 (1.31%) 
      EMR's had concurrent GP, respectively. The remainder 19,810 EMRs with a diagnosis 
      of GP were classified as having idiopathic GP. In all three subgroups, women and 
      Caucasians had the highest prevalence of GP. The diagnosis of GP was confirmed by 
      both GES and EGD in 9,950 of patients (14.22%). For patients with T1DM, T2DM, or 
      idiopathic GP, GP was confirmed by both diagnostic tests in 16.8%, 14.0%, and 
      13.2%, respectively. CONCLUSIONS: Our estimated rates of prevalence of GP in T1DM 
      and T2DM indicate that GP is not a common clinical complication in these 
      populations. Majority of EMRs that indicated a diagnosis of GP did not include 
      any documentation of definitive diagnostic testing (EGD and/or GES).
FAU - Syed, Aslam R
AU  - Syed AR
AD  - Department of Internal Medicine.
AD  - Division of Gastroenterology, Allegheny Health Network, Pittsburgh, PA.
FAU - Wolfe, Michael M
AU  - Wolfe MM
AD  - Department of Internal Medicine.
AD  - Division of Gastroenterology and Hepatology.
FAU - Calles-Escandon, Jorge
AU  - Calles-Escandon J
AD  - Department of Internal Medicine.
AD  - Division of Endocrinology and Metabolism, MetroHealth Medical Center, Case 
      Western Reserve University, Cleveland, OH.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Clin Gastroenterol
JT  - Journal of clinical gastroenterology
JID - 7910017
SB  - IM
CIN - J Clin Gastroenterol. 2020 Jan;54(1):106. PMID: 31702589
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 1/epidemiology
MH  - Diabetes Mellitus, Type 2/epidemiology
MH  - Diagnosis, Differential
MH  - Endoscopy, Digestive System
MH  - Female
MH  - Gastric Emptying
MH  - Gastroparesis/*diagnosis/*epidemiology
MH  - Health Surveys
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - United States/epidemiology
MH  - Young Adult
PMC - PMC6903337
EDAT- 2019/05/29 06:00
MHDA- 2021/04/29 06:00
PMCR- 2019/12/10
CRDT- 2019/05/29 06:00
PHST- 2019/05/29 06:00 [pubmed]
PHST- 2021/04/29 06:00 [medline]
PHST- 2019/05/29 06:00 [entrez]
PHST- 2019/12/10 00:00 [pmc-release]
AID - 00004836-202001000-00009 [pii]
AID - 10.1097/MCG.0000000000001231 [doi]
PST - ppublish
SO  - J Clin Gastroenterol. 2020 Jan;54(1):50-54. doi: 10.1097/MCG.0000000000001231.