PMID- 31137065
OWN - NLM
STAT- MEDLINE
DCOM- 20200429
LR  - 20200429
IS  - 1098-9048 (Electronic)
IS  - 1069-3424 (Linking)
VI  - 40
IP  - 2
DP  - 2019 Apr
TI  - Interstitial Pneumonia with Autoimmune Features and Undifferentiated Connective 
      Tissue Disease.
PG  - 271-277
LID - 10.1055/s-0039-1684007 [doi]
AB  - In 2015, a multidisciplinary task force comprising pulmonologists, 
      rheumatologists, pathologists, and radiologists representing the European 
      Respiratory Society and American Thoracic Society published a diagnostic 
      classification schema for individuals with interstitial lung disease and 
      autoimmune features who did not meet criteria for a defined connective tissue 
      disease. The term interstitial pneumonia with autoimmune features (IPAF) was 
      applied. Classification criteria are often nonspecific, but up to 90% of subjects 
      with IPAF have serological evidence for autoimmunity (particularly (+) 
      antinuclear antibodies). Distinguishing patients with IPAF from idiopathic 
      pulmonary disorders may be difficult. The natural history and appropriate 
      management of IPAF have not been clarified, as data are largely limited to 
      retrospective studies. In this review, we discuss the salient clinical, 
      serologic, histologic, and radiographic features of IPAF and discuss an approach 
      to management.
CI  - Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.
FAU - Chernau, Andrea K
AU  - Chernau AK
AD  - Rocky Vista University College of Osteopathic Medicine, Parker, Colorado.
FAU - Leone, Paolo M
AU  - Leone PM
AD  - Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
AD  - Universita Cattolica del Sacro Cuore, Roma, Italy.
AD  - Interstitial Lung Disease Program, National Jewish Health, Denver, Colorado.
FAU - Swigris, Jeffrey J
AU  - Swigris JJ
AD  - Interstitial Lung Disease Program, National Jewish Health, Denver, Colorado.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190528
PL  - United States
TA  - Semin Respir Crit Care Med
JT  - Seminars in respiratory and critical care medicine
JID - 9431858
SB  - IM
MH  - *Autoimmunity
MH  - Humans
MH  - Lung Diseases, Interstitial/classification/complications/diagnosis/*immunology
MH  - Undifferentiated Connective Tissue Diseases/complications/diagnosis/*immunology
COIS- None declared.
EDAT- 2019/05/29 06:00
MHDA- 2020/04/30 06:00
CRDT- 2019/05/29 06:00
PHST- 2019/05/29 06:00 [entrez]
PHST- 2019/05/29 06:00 [pubmed]
PHST- 2020/04/30 06:00 [medline]
AID - 10.1055/s-0039-1684007 [doi]
PST - ppublish
SO  - Semin Respir Crit Care Med. 2019 Apr;40(2):271-277. doi: 10.1055/s-0039-1684007. 
      Epub 2019 May 28.