PMID- 31140828 OWN - NLM STAT- MEDLINE DCOM- 20200320 LR - 20200320 IS - 1752-0371 (Electronic) IS - 1752-0363 (Linking) VI - 13 IP - 7 DP - 2019 May TI - Inflammation level and renal function injury in antineutrophil cytoplasmic antibody-associated vasculitis: a correlation with low albumin and high-density lipoprotein. PG - 557-565 LID - 10.2217/bmm-2018-0303 [doi] AB - Aim: To explore the correlation of inflammation level and organ involvement in antineutrophil cytoplasmic antibody-associated vasculitis (AAV) patients with Alb and HDL. Materials & methods: Serum levels of Alb and HDL were measured, with AAV patients being grouped according to serum Alb and HDL levels, and indicators reflecting inflammation and renal injury were compared. Results: Serum levels of creatinine (Cr), uric acid and CRP and renal involvement rates were higher in lower Alb patients; Cr, CRP, renal and cardiovascular involvement rates in lower HDL patients were higher. Alb and HDL were negatively correlated with CRP and erythrocyte sedimentation rate. Conclusion: Serum Alb and HDL were good indictors for disease monitoring in AAV. FAU - Zeng, Tingting AU - Zeng T AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. FAU - Tian, Yongjian AU - Tian Y AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. FAU - Tan, Liming AU - Tan L AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. FAU - Wu, Yang AU - Wu Y AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. FAU - Yu, Jianlin AU - Yu J AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. FAU - Huang, Jiayi AU - Huang J AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. FAU - Pei, Zihuang AU - Pei Z AD - The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, No. 1 Minde Road, Donghu District, Nanchang 330006, Jiangxi, PR China. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20190529 PL - England TA - Biomark Med JT - Biomarkers in medicine JID - 101312535 RN - 0 (Lipoproteins, HDL) RN - 9007-41-4 (C-Reactive Protein) RN - ZIF514RVZR (Serum Albumin, Human) SB - IM MH - Aged MH - Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis/metabolism/*physiopathology MH - C-Reactive Protein/metabolism MH - Female MH - Humans MH - Inflammation/metabolism/physiopathology MH - Kidney/*physiopathology MH - Lipoproteins, HDL/*blood MH - Male MH - Middle Aged MH - Serum Albumin, Human/*metabolism OTO - NOTNLM OT - ANCA associated vasculitis OT - C-reactive protein OT - albumin OT - antineutrophil cytoplasmic antibody OT - creatinine OT - erythrocyte sedimentation rate OT - estimated glomerular filtration rate OT - high-density lipoprotein OT - organ involvement OT - uric acid EDAT- 2019/05/30 06:00 MHDA- 2020/03/21 06:00 CRDT- 2019/05/30 06:00 PHST- 2019/05/30 06:00 [pubmed] PHST- 2020/03/21 06:00 [medline] PHST- 2019/05/30 06:00 [entrez] AID - 10.2217/bmm-2018-0303 [doi] PST - ppublish SO - Biomark Med. 2019 May;13(7):557-565. doi: 10.2217/bmm-2018-0303. Epub 2019 May 29.