PMID- 31143697
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220408
IS  - 2231-0770 (Print)
IS  - 2249-4464 (Electronic)
IS  - 2231-0770 (Linking)
VI  - 9
IP  - 2
DP  - 2019 Apr-Jun
TI  - Left ventricular dyssynchrony assessment using tissue synchronization imaging in 
      acute myocardial infarction.
PG  - 48-54
LID - 10.4103/ajm.AJM_168_18 [doi]
AB  - OBJECTIVES: To assess left ventricular (LV) dyssynchrony in patients with ST 
      elevation myocardial infarction (STEMI). BACKGROUND: Mechanical synchronization 
      disorder leads to a decrease in LV ejection fraction (LVEF) and stroke volume, an 
      abnormal distribution of wall tension, and increase in workload during cardiac 
      contraction. METHODS: We enrolled 56 participants, 36 with acute STEMI and 20 
      healthy controls. The automatically color-coded time to peak myocardial velocity 
      was measured using a 6mm sample volume, manually positioned within the 
      two-dimensional-tissue strain image of the 12 basal and middle LV segments. 
      RESULTS: A significant delay was found between the septal-lateral and 
      septal-posterior walls in patients with STEMI compared to patients in the control 
      group (36.36 vs. -6.0ms, P = 0.036; and 42.7 vs. 23.94ms, P = 0.042, 
      respectively). Furthermore, all segment maximum differences and all segment 
      standard deviation (SD; dyssynchrony index) were found to be significantly higher 
      in the STEMI group (131.28 vs. 95.45ms, P = 0.013; and 44.47 vs. 26.45ms, P = 
      0.001, respectively). A significant delay between the septal-lateral walls and 
      septal-posterior walls, all segment maximum difference, and all segment SD 
      (dyssynchrony index) were found in patients with complicated STEMI (70.89 vs. 
      15.83ms, P = 0.038; 57.44 vs. 19.06ms, P = 0.040; 138.11 vs. 100.0ms, P = 0.035; 
      and 45.44 vs. 32.50ms, P = 0.021, respectively). There was a significant negative 
      correlation between tissue synchronization imaging parameters and LVEF, and a 
      positive correlation with LV end systolic dimension. CONCLUSION: Patients with 
      acute STEMI showed significant LV dyssynchrony, which was an independent 
      predictor of inhospital complications.
FAU - Azazy, Ahmed S
AU  - Azazy AS
AD  - Department of Cardiology, King Saud Medical City, Riyadh, Saudi Arabia.
FAU - Soliman, Mahmoud
AU  - Soliman M
AD  - Department of Cardiology, Meoufiya University Hospital, Meoufiya, Egypt.
FAU - Yaseen, Rehab
AU  - Yaseen R
AD  - Department of Cardiology, Meoufiya University Hospital, Meoufiya, Egypt.
FAU - Mena, Morad
AU  - Mena M
AD  - Department of Cardiology, Meoufiya University Hospital, Meoufiya, Egypt.
FAU - Sakr, Haitham
AU  - Sakr H
AD  - Department of Cardiology, King Saud Medical City, Riyadh, Saudi Arabia.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Avicenna J Med
JT  - Avicenna journal of medicine
JID - 101584155
PMC - PMC6530268
OTO - NOTNLM
OT  - Left ventricular dyssynchrony
OT  - myocardial infarction
OT  - tissue synchronization imaging
COIS- There are no conflicts of interest.
EDAT- 2019/05/31 06:00
MHDA- 2019/05/31 06:01
PMCR- 2019/04/01
CRDT- 2019/05/31 06:00
PHST- 2019/05/31 06:00 [entrez]
PHST- 2019/05/31 06:00 [pubmed]
PHST- 2019/05/31 06:01 [medline]
PHST- 2019/04/01 00:00 [pmc-release]
AID - AJM-9-48 [pii]
AID - 10.4103/ajm.AJM_168_18 [doi]
PST - ppublish
SO  - Avicenna J Med. 2019 Apr-Jun;9(2):48-54. doi: 10.4103/ajm.AJM_168_18.