PMID- 31152518
OWN - NLM
STAT- MEDLINE
DCOM- 20190731
LR  - 20190731
IS  - 1872-2059 (Electronic)
IS  - 1000-8713 (Linking)
VI  - 37
IP  - 6
DP  - 2019 Jun 8
TI  - [Simultaneous determination of vitamins B(1), B(2), B(6), niacinamide and calcium 
      pantothenate in compound vitamin B tablets by high performance quantitative 
      capillary electrophoresis].
PG  - 661-665
LID - 10.3724/SP.J.1123.2018.12040 [doi]
AB  - A high performance quantitative capillary electrophoresis method was developed 
      for the simultaneous determination of vitamins B(1), B(2), B(6), nicotinamide, 
      and calcium pantothenate in vitamin B tablets using a quantitative capillary 
      electrophoresis instrument. The samples were extracted ultrasonically with 
      acetonitrile-water (20:80, v/v). The automatic high precision quantitative 
      capillary electrophoresis instrument was used to realize quantitative injection 
      through a 10 nL injection valve. The background electrolyte was selected as 40 
      mmol/L sodium borate buffer (pH 9.0), which was continuously supplied by a 
      microfluidic injection pump. The working voltage was -10 kV. The detection 
      wavelength of vitamins B(1), B(2), B(6), and nicotinamide was selected as 280 nm, 
      which was then changed to 210 nm to detect calcium pantothenate. The result 
      showed good linearities between the peak area and the concentration of vitamins 
      B(1), B(2), B(6), nicotinamide, and calcium pantothenate in the correlation 
      coefficients (r) range of 0.9968-0.9998. The limits of detection (LODs) were in 
      the range of 2.5-36.0 mg/L. The average recoveries were 94.1%-98.9% with relative 
      standard deviations (RSDs) as 1.3%-1.9%. The method is precise, reliable, and 
      suitable for the simultaneous determination of vitamins B(1), B(2), B(6), 
      nicotinamide, and calcium pantothenate in a real compound vitamin B tablet.
FAU - Hu, Wenwen
AU  - Hu W
AD  - School of Chemical and Environmental Engineering, Shanghai Institute of 
      Technology, Shanghai 201418, China.
FAU - Tao, Jianwei
AU  - Tao J
AD  - School of Chemical and Environmental Engineering, Shanghai Institute of 
      Technology, Shanghai 201418, China.
FAU - Wang, Qingwei
AU  - Wang Q
AD  - School of Chemical and Environmental Engineering, Shanghai Institute of 
      Technology, Shanghai 201418, China.
FAU - Li, Jing
AU  - Li J
AD  - Unimicro Technologies, Inc., Shanghai 201203, China.
FAU - Yan, Chao
AU  - Yan C
AD  - Unimicro Technologies, Inc., Shanghai 201203, China.
AD  - Pharmacy School, Shanghai Jiaotong University, Shanghai 200240, China.
FAU - Xu, Xu
AU  - Xu X
AD  - School of Chemical and Environmental Engineering, Shanghai Institute of 
      Technology, Shanghai 201418, China.
LA  - chi
PT  - Journal Article
PL  - China
TA  - Se Pu
JT  - Se pu = Chinese journal of chromatography
JID - 9424804
RN  - 0 (Tablets)
RN  - 12001-76-2 (Vitamin B Complex)
RN  - 19F5HK2737 (Pantothenic Acid)
RN  - 25X51I8RD4 (Niacinamide)
RN  - 8059-24-3 (Vitamin B 6)
RN  - TLM2976OFR (Riboflavin)
RN  - X66NSO3N35 (Thiamine)
MH  - Electrophoresis, Capillary
MH  - Niacinamide/analysis
MH  - Pantothenic Acid/analysis
MH  - Riboflavin/analysis
MH  - Tablets
MH  - Thiamine/analysis
MH  - Vitamin B 6/analysis
MH  - Vitamin B Complex/*analysis
OTO - NOTNLM
OT  - capillary electrophoresis (CE)
OT  - compound vitamin B tablets
OT  - content determination
EDAT- 2019/06/04 06:00
MHDA- 2019/08/01 06:00
CRDT- 2019/06/02 06:00
PHST- 2019/06/02 06:00 [entrez]
PHST- 2019/06/04 06:00 [pubmed]
PHST- 2019/08/01 06:00 [medline]
AID - 10.3724/SP.J.1123.2018.12040 [doi]
PST - ppublish
SO  - Se Pu. 2019 Jun 8;37(6):661-665. doi: 10.3724/SP.J.1123.2018.12040.