PMID- 31153010
OWN - NLM
STAT- MEDLINE
DCOM- 20200330
LR  - 20200330
IS  - 1872-7123 (Electronic)
IS  - 0165-1781 (Linking)
VI  - 278
DP  - 2019 Aug
TI  - The association between cannabis use and psychiatric comorbidity in people with 
      personality disorders: A population-based longitudinal study.
PG  - 70-77
LID - S0165-1781(19)30866-2 [pii]
LID - 10.1016/j.psychres.2019.05.041 [doi]
AB  - Both personality disorders (PD) and cannabis use are highly comorbid with various 
      psychiatric disorders. While previous research indicates specific interactions 
      between cannabis use and schizotypal PD associated with schizophrenia, research 
      into cannabis use among individuals with other PDs and the development of several 
      additional psychiatric disorders is scarce. We explored the prevalence and 
      incidence of psychiatric disorders among individuals with PDs who use cannabis, 
      and whether individuals with PDs who use cannabis are at increased risk for 
      developing psychiatric disorders compared to cannabis users without a PD. 
      Finally, we examined the interaction effect between cannabis use and personality 
      disorders on comorbid psychiatric disorders. Data from 34,653 participants in 
      waves 1 and 2 of the National Epidemiologic Survey on Alcohol and Related 
      Conditions (NESARC) were analyzed. Our findings indicate that individuals with 
      PDs who used cannabis were at increased odds for developing substance use 
      disorders (including opioid use disorder), but not other comorbid psychiatric 
      disorders, at 3-year follow up. No significant interaction effects were generally 
      found between cannabis use and PD. These findings suggest that aside from 
      specific substance use disorders, individuals with PDs are not at an increased 
      risk for developing other psychiatric disorders following cannabis use.
CI  - Copyright (c) 2019 Elsevier B.V. All rights reserved.
FAU - Shalit, Nadav
AU  - Shalit N
AD  - Lev-Hasharon Mental Health Center, Pardesiya, Israel; Sackler Faculty of 
      Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: 
      nadavs@lev-hasharon.co.il.
FAU - Rehm, Jurgen
AU  - Rehm J
AD  - Centre for Addiction and Mental Health, Institute for Mental Health Policy 
      Research, Toronto, Ontario, Canada; Dalla Lana School of Public Health, 
      University of Toronto, Toronto, Ontario, Canada; Klinische Psychologie & 
      Psychotherapie, Technische Universitat Dresden, Dresden, Germany.
FAU - Lev-Ran, Shaul
AU  - Lev-Ran S
AD  - Lev-Hasharon Mental Health Center, Pardesiya, Israel; Centre for Addiction and 
      Mental Health, Institute for Mental Health Policy Research, Toronto, Ontario, 
      Canada; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
LA  - eng
PT  - Journal Article
DEP - 20190527
PL  - Ireland
TA  - Psychiatry Res
JT  - Psychiatry research
JID - 7911385
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Comorbidity
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Marijuana Use/*epidemiology
MH  - Mental Disorders/*epidemiology
MH  - Middle Aged
MH  - Personality Disorders/*epidemiology
MH  - Prevalence
MH  - Substance-Related Disorders/*epidemiology
MH  - Young Adult
OTO - NOTNLM
OT  - Cannabis
OT  - NESARC
OT  - Personality disorders
EDAT- 2019/06/04 06:00
MHDA- 2020/03/31 06:00
CRDT- 2019/06/02 06:00
PHST- 2019/04/15 00:00 [received]
PHST- 2019/05/25 00:00 [revised]
PHST- 2019/05/25 00:00 [accepted]
PHST- 2019/06/04 06:00 [pubmed]
PHST- 2020/03/31 06:00 [medline]
PHST- 2019/06/02 06:00 [entrez]
AID - S0165-1781(19)30866-2 [pii]
AID - 10.1016/j.psychres.2019.05.041 [doi]
PST - ppublish
SO  - Psychiatry Res. 2019 Aug;278:70-77. doi: 10.1016/j.psychres.2019.05.041. Epub 
      2019 May 27.