PMID- 31154005
OWN - NLM
STAT- MEDLINE
DCOM- 20200911
LR  - 20240214
IS  - 1873-6815 (Electronic)
IS  - 0531-5565 (Print)
IS  - 0531-5565 (Linking)
VI  - 124
DP  - 2019 Sep
TI  - Movement-evoked pain, physical function, and perceived stress: An observational 
      study of ethnic/racial differences in aging non-Hispanic Blacks and non-Hispanic 
      Whites with knee osteoarthritis.
PG  - 110622
LID - S0531-5565(19)30246-3 [pii]
LID - 10.1016/j.exger.2019.05.011 [doi]
AB  - BACKGROUND: Knee osteoarthritis (OA) is a pervasive musculoskeletal condition, 
      often exacerbated by movement-evoked pain (MEP). Despite established research 
      demonstrating significant racial differences in OA pain, few studies have 
      investigated ethnic/racial group differences in MEP and lower extremity function 
      and their association with psychosocial factors, such as perceived stress. 
      Therefore, the primary aims were: (1) to identify ethnic/racial group differences 
      in persons with or at risk for knee OA pain based on MEP, physical performance, 
      and perceived stress measures, and (2) to determine if perceived stress explains 
      the relationship between MEP and function in non-Hispanic Blacks (NHBs) and 
      non-Hispanic Whites (NHWs). METHODS: A total of 162 NHB and NHW 
      community-dwelling older adults (50-78 years of age) were included in this 
      analysis from the Understanding Pain and Limitations in Osteoarthritic Disease 
      (UPLOAD) cross-sectional cohort study. Demographic, anthropometric, pain and 
      functional parameters were assessed using a battery of validated instruments. 
      Descriptive statistics, parametric, and multivariate analyses were conducted to 
      determine ethnic/racial differences in perceived stress, MEP, and function. 
      RESULTS: Our results support the hypothesis that among persons with knee OA pain, 
      NHBs have significantly greater MEP and lower functional level, despite similar 
      levels of perceived stress. However, perceived stress was more strongly related 
      to MEP in NHB compared to NHWs. Differences in function were limited to walking 
      speed, where NHWs demonstrated faster gait speed. CONCLUSIONS: Our 
      cross-sectional study demonstrated important ethnic/racial differences in MEP and 
      function. Also, perceived stress had a stronger effect on MEP in NHBs, suggesting 
      that perceived stress may more strongly influence pain with physical movement 
      among NHB adults. MEP may be a clinically important pain outcome to measure in 
      persons with OA, and these data warrant future research on the impact of stress 
      on pain and functional outcomes in older adults, particularly in NHBs.
CI  - Copyright (c) 2019 Elsevier Inc. All rights reserved.
FAU - Booker, Staja
AU  - Booker S
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA. Electronic 
      address: sbooker@dental.ufl.edu.
FAU - Cardoso, Josue
AU  - Cardoso J
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA.
FAU - Cruz-Almeida, Yenisel
AU  - Cruz-Almeida Y
AD  - The University of Florida, Pain Research and Intervention Center of Excellence, 
      Gainesville, FL 32610, USA; The University of Florida, Department of Aging & 
      Geriatric Research, College of Medicine, Gainesville, FL 32611, USA.
FAU - Sibille, Kimberly T
AU  - Sibille KT
AD  - The University of Florida, Pain Research and Intervention Center of Excellence, 
      Gainesville, FL 32610, USA; The University of Florida, Department of Aging & 
      Geriatric Research, College of Medicine, Gainesville, FL 32611, USA.
FAU - Terry, Ellen L
AU  - Terry EL
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA.
FAU - Powell-Roach, Keesha L
AU  - Powell-Roach KL
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA.
FAU - Riley, Joseph L 3rd
AU  - Riley JL 3rd
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA.
FAU - Goodin, Burel R
AU  - Goodin BR
AD  - University of Alabama at Birmingham, Department of Psychology, Birmingham, AL 
      35294, USA.
FAU - Bartley, Emily J
AU  - Bartley EJ
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA.
FAU - Addison, Adriana Sotolongo
AU  - Addison AS
AD  - University of Alabama at Birmingham, Department of Psychology, Birmingham, AL 
      35294, USA.
FAU - Staud, Roland
AU  - Staud R
AD  - The University of Florida, Department of Medicine, Gainesville, FL 32608, USA.
FAU - Redden, David
AU  - Redden D
AD  - University of Alabama at Birmingham, Department of Biostatistics, Birmingham, AL 
      35294, USA; University of Alabama at Birmingham, Department Medicine and 
      Rheumatology, Birmingham, AL 35294, USA.
FAU - Bradley, Laurence
AU  - Bradley L
AD  - University of Alabama at Birmingham, Division of Clinical Immunology and 
      Rheumatology, Birmingham, AL 35294, USA.
FAU - Fillingim, Roger B
AU  - Fillingim RB
AD  - The University of Florida, Department of Community Dentistry and Behavioral 
      Science, Gainesville, FL 32610, USA; The University of Florida, Pain Research and 
      Intervention Center of Excellence, Gainesville, FL 32610, USA.
LA  - eng
GR  - UL1 TR000064/TR/NCATS NIH HHS/United States
GR  - UL1 TR000165/TR/NCATS NIH HHS/United States
GR  - K07 AG046371/AG/NIA NIH HHS/United States
GR  - K22 NS102334/NS/NINDS NIH HHS/United States
GR  - P30 AG028740/AG/NIA NIH HHS/United States
GR  - R37 AG033906/AG/NIA NIH HHS/United States
GR  - R01 AG054370/AG/NIA NIH HHS/United States
GR  - T32 AG049673/AG/NIA NIH HHS/United States
GR  - P30 AG059297/AG/NIA NIH HHS/United States
GR  - R00 AG052642/AG/NIA NIH HHS/United States
GR  - K99 AG052642/AG/NIA NIH HHS/United States
PT  - Journal Article
PT  - Multicenter Study
PT  - Observational Study
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
DEP - 20190530
PL  - England
TA  - Exp Gerontol
JT  - Experimental gerontology
JID - 0047061
SB  - IM
MH  - *Black or African American
MH  - Aged
MH  - Aged, 80 and over
MH  - *Aging
MH  - Female
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Osteoarthritis, Knee/*ethnology/*psychology
MH  - Pain/*ethnology/*psychology
MH  - Physical Functional Performance
MH  - Prospective Studies
MH  - Severity of Illness Index
MH  - Stress, Psychological
MH  - United States
MH  - *White People
PMC - PMC6660381
MID - NIHMS1531884
OTO - NOTNLM
OT  - Ethnicity/race
OT  - Function
OT  - Movement
OT  - Osteoarthritis
OT  - Pain
OT  - Stress
COIS- Declaration of Interests: None
EDAT- 2019/06/04 06:00
MHDA- 2020/09/12 06:00
PMCR- 2020/09/01
CRDT- 2019/06/03 06:00
PHST- 2019/04/01 00:00 [received]
PHST- 2019/05/23 00:00 [revised]
PHST- 2019/05/24 00:00 [accepted]
PHST- 2019/06/04 06:00 [pubmed]
PHST- 2020/09/12 06:00 [medline]
PHST- 2019/06/03 06:00 [entrez]
PHST- 2020/09/01 00:00 [pmc-release]
AID - S0531-5565(19)30246-3 [pii]
AID - 10.1016/j.exger.2019.05.011 [doi]
PST - ppublish
SO  - Exp Gerontol. 2019 Sep;124:110622. doi: 10.1016/j.exger.2019.05.011. Epub 2019 
      May 30.