PMID- 31157991
OWN - NLM
STAT- MEDLINE
DCOM- 20190719
LR  - 20190719
IS  - 1744-5205 (Electronic)
IS  - 0882-0538 (Linking)
VI  - 34
IP  - 4
DP  - 2019
TI  - Diagnosis and Imaging of Optic Nerve Head Drusen.
PG  - 256-263
LID - 10.1080/08820538.2019.1620804 [doi]
AB  - The presence of optic nerve swelling in pediatric patients is a frequent cause 
      for referral to pediatric ophthalmologists and neuro-ophthalmologists because 
      this finding can be the harbinger of serious neurologic disease including brain 
      tumor, demyelinating disease, infiltrative disease of the optic nerve, or 
      idiopathic intracranial hypertension. Optic nerve head drusen (ONHD) are common 
      and can be particularly difficult to distinguish from true optic nerve swelling 
      in pediatric patients because the ONHD are typically buried beneath the substance 
      of the optic nerve. Correct identification of ONHD is relevant because of the 
      visual morbidity associated with this condition and because of the need to 
      distinguish pseudopapilledema secondary to ONHD from true optic nerve swelling. A 
      variety of imaging modalities may be employed to evaluate for the presence of 
      ONHD, including ultrasound, optical coherence tomography (OCT), enhanced depth 
      imaging-OCT, fluorescein angiography, fundus autofluorescence, and optical 
      coherence tomography angiography. To date, there is no consensus as to which of 
      these techniques is most accurate and which should be part of a standardized 
      evaluation for children suspected of ONHD. This review examines the recent 
      literature analyzing these diagnostic tools and summarizes data regarding best 
      practices for identifying ONHD.
FAU - Gise, Ryan
AU  - Gise R
AD  - a Department of Ophthalmology, Massachusetts Eye and Ear Infirmary , Harvard 
      Medical School , Boston , MA , USA.
FAU - Gaier, Eric D
AU  - Gaier ED
AD  - a Department of Ophthalmology, Massachusetts Eye and Ear Infirmary , Harvard 
      Medical School , Boston , MA , USA.
AD  - b Department of Ophthalmology, Harvard Medical School , Boston Children's 
      Hospital , Boston , MA , USA.
FAU - Heidary, Gena
AU  - Heidary G
AD  - a Department of Ophthalmology, Massachusetts Eye and Ear Infirmary , Harvard 
      Medical School , Boston , MA , USA.
AD  - b Department of Ophthalmology, Harvard Medical School , Boston Children's 
      Hospital , Boston , MA , USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20190603
PL  - England
TA  - Semin Ophthalmol
JT  - Seminars in ophthalmology
JID - 8610759
SB  - IM
MH  - *Diagnostic Techniques, Ophthalmological
MH  - Fluorescein Angiography/methods
MH  - Humans
MH  - Optic Disk/*diagnostic imaging
MH  - Optic Disk Drusen/*diagnostic imaging
MH  - Optical Imaging/*methods
MH  - Tomography, Optical Coherence/methods
MH  - Ultrasonography/methods
OTO - NOTNLM
OT  - EDI-OCT
OT  - Optic nerve head drusen
OT  - ocular coherence tomography
OT  - optic nerve head imaging
OT  - vision loss
EDAT- 2019/06/04 06:00
MHDA- 2019/07/20 06:00
CRDT- 2019/06/04 06:00
PHST- 2019/06/04 06:00 [pubmed]
PHST- 2019/07/20 06:00 [medline]
PHST- 2019/06/04 06:00 [entrez]
AID - 10.1080/08820538.2019.1620804 [doi]
PST - ppublish
SO  - Semin Ophthalmol. 2019;34(4):256-263. doi: 10.1080/08820538.2019.1620804. Epub 
      2019 Jun 3.