PMID- 31161446
OWN - NLM
STAT- MEDLINE
DCOM- 20200319
LR  - 20200319
IS  - 1867-0687 (Electronic)
IS  - 1708-8569 (Print)
VI  - 15
IP  - 5
DP  - 2019 Oct
TI  - Management of Wilms tumor with intravenous thrombus in children: a single center 
      experience.
PG  - 476-482
LID - 10.1007/s12519-019-00272-0 [doi]
AB  - BACKGROUND: Wilms tumor tends to grow into vena cava, even invade atrium, which 
      increased operating difficulty and frequency of surgical complications. METHODS: 
      Forty-two patients of Wilms tumor with intravenous thrombus were retrospective 
      studied. The diagnosis and therapy were discussed according to the medical 
      records and interrelated literatures. RESULTS: Forty-two children with thrombus 
      were diagnosed by computed tomography and 41 cases by ultrasound simultaneously. 
      36 children had received preoperative chemotherapy. Surgical resection was 
      performed in all patients. Cardiopulmonary bypass was used for the removal of the 
      intra-atrial thrombus in 5 patients. There were no surgical complications 
      occurred. The patients received chemotherapy and radiotherapy according to 
      clinical staging by National Wilms' Tumor Study (NWTS)-4 or NWTS-5. 34 patients 
      were successfully followed up, 32 patients survive at present, including one who 
      has been followed up more than 20 years since operation. CONCLUSION: Standardized 
      sequential treatment, including preoperative chemotherapy and radiotherapy, 
      nephrectomy combining resection of thrombus, postoperative adjuvant therapy, is 
      the mainstay of treatment of Wilms tumor with intravenous thrombus.
FAU - Xu, Shuai
AU  - Xu S
AD  - Department of Urology Surgery, Beijing Children's Hospital Affiliated to Capital 
      Medical University, National Center for Children's Health, 56 South Lishi Road, 
      Xicheng District, Beijing 100045, China.
FAU - Sun, Ning
AU  - Sun N
AD  - Department of Urology Surgery, Beijing Children's Hospital Affiliated to Capital 
      Medical University, National Center for Children's Health, 56 South Lishi Road, 
      Xicheng District, Beijing 100045, China. sunning_bch@163.com.
FAU - Zhang, Wei-Ping
AU  - Zhang WP
AD  - Department of Urology Surgery, Beijing Children's Hospital Affiliated to Capital 
      Medical University, National Center for Children's Health, 56 South Lishi Road, 
      Xicheng District, Beijing 100045, China.
FAU - Song, Hong-Cheng
AU  - Song HC
AD  - Department of Urology Surgery, Beijing Children's Hospital Affiliated to Capital 
      Medical University, National Center for Children's Health, 56 South Lishi Road, 
      Xicheng District, Beijing 100045, China.
FAU - Huang, Cheng-Ru
AU  - Huang CR
AD  - Department of Urology Surgery, Beijing Children's Hospital Affiliated to Capital 
      Medical University, National Center for Children's Health, 56 South Lishi Road, 
      Xicheng District, Beijing 100045, China.
LA  - eng
PT  - Journal Article
DEP - 20190603
PL  - Switzerland
TA  - World J Pediatr
JT  - World journal of pediatrics : WJP
JID - 101278599
SB  - IM
MH  - Child, Preschool
MH  - China
MH  - Combined Modality Therapy
MH  - Coronary Thrombosis/diagnostic imaging/*etiology/*therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Neoplasm Staging
MH  - Nephrectomy
MH  - Retrospective Studies
MH  - Venous Thrombosis/diagnostic imaging/*etiology/*therapy
MH  - Wilms Tumor/*complications/diagnostic imaging/*therapy
PMC - PMC6785647
OTO - NOTNLM
OT  - Experience
OT  - Intravenous thrombus
OT  - Management
OT  - Wilms tumor
COIS- No financial or nonfinancial benefits have been received or will be received from 
      any party related directly or indirectly to the subject of this article.
EDAT- 2019/06/05 06:00
MHDA- 2020/03/20 06:00
PMCR- 2019/06/03
CRDT- 2019/06/05 06:00
PHST- 2019/03/22 00:00 [received]
PHST- 2019/05/23 00:00 [accepted]
PHST- 2019/06/05 06:00 [pubmed]
PHST- 2020/03/20 06:00 [medline]
PHST- 2019/06/05 06:00 [entrez]
PHST- 2019/06/03 00:00 [pmc-release]
AID - 10.1007/s12519-019-00272-0 [pii]
AID - 272 [pii]
AID - 10.1007/s12519-019-00272-0 [doi]
PST - ppublish
SO  - World J Pediatr. 2019 Oct;15(5):476-482. doi: 10.1007/s12519-019-00272-0. Epub 
      2019 Jun 3.