PMID- 31161533 OWN - NLM STAT- MEDLINE DCOM- 20210604 LR - 20230315 IS - 1573-2614 (Electronic) IS - 1387-1307 (Linking) VI - 34 IP - 2 DP - 2020 Apr TI - Non-invasive continuous respiratory monitoring using temperature-based sensors. PG - 223-231 LID - 10.1007/s10877-019-00329-5 [doi] AB - Respiratory rate (RR) is a key vital sign that has been traditionally employed in the clinical assessment of patients and in the prevention of respiratory compromise. Despite its relevance, current practice for monitoring RR in non-intubated patients strongly relies on visual counting, which delivers an intermittent and error-prone assessment of the respiratory status. Here, we present a novel non-invasive respiratory monitor that continuously measures the RR in human subjects. The respiratory activity of the user is inferred by sensing the thermal transfer between the breathing airflow and a temperature sensor placed between the nose and the mouth. The performance of the respiratory monitor is assessed through respiratory experiments performed on healthy subjects. Under spontaneous breathing, the mean RR difference between our respiratory monitor and visual counting was 0.4 breaths per minute (BPM), with a 95% confidence interval equal to [- 0.5, 1.3] BPM. The robustness of the respiratory sensor to the position is assessed by studying the signal-to-noise ratio in different locations on the upper lip, displaying a markedly better performance than traditional thermal sensors used for respiratory airflow measurements. FAU - Hurtado, Daniel E AU - Hurtado DE AUID- ORCID: 0000-0001-6261-9106 AD - Department of Structural and Geotechnical Engineering, School of Engineering, and Institute for Biological and Medical Engineering, Schools of Engineering, Medicine and Biological Sciences, Pontificia Universidad Catolica de Chile, Vicuna Mackenna 4860, Santiago, Chile. dhurtado@ing.puc.cl. FAU - Abusleme, Angel AU - Abusleme A AD - Department of Electrical Engineering, School of Engineering, Pontificia Universidad Catolica de Chile, Vicuna Mackenna, 4860, Santiago, Chile. FAU - Chavez, Javier A P AU - Chavez JAP AD - DICTUC S.A., Vicuna Mackenna, 4860, Santiago, Chile. LA - eng GR - 17ITE2-72695/CORFO/ GR - 2015.R.557/Fundacion Copec-UC/ PT - Evaluation Study PT - Journal Article DEP - 20190603 PL - Netherlands TA - J Clin Monit Comput JT - Journal of clinical monitoring and computing JID - 9806357 SB - IM CIN - J Clin Monit Comput. 2020 Apr;34(2):221-222. PMID: 31342305 MH - Adolescent MH - Adult MH - Aged MH - Equipment Design MH - Female MH - Humans MH - Male MH - Middle Aged MH - Monitoring, Physiologic/*instrumentation/methods/statistics & numerical data MH - Respiration MH - *Respiratory Rate MH - Signal-To-Noise Ratio MH - Temperature MH - Young Adult OTO - NOTNLM OT - Monitoring OT - Respiration OT - Thermal sensors EDAT- 2019/06/05 06:00 MHDA- 2021/06/05 06:00 CRDT- 2019/06/05 06:00 PHST- 2018/12/07 00:00 [received] PHST- 2019/05/29 00:00 [accepted] PHST- 2019/06/05 06:00 [pubmed] PHST- 2021/06/05 06:00 [medline] PHST- 2019/06/05 06:00 [entrez] AID - 10.1007/s10877-019-00329-5 [pii] AID - 10.1007/s10877-019-00329-5 [doi] PST - ppublish SO - J Clin Monit Comput. 2020 Apr;34(2):223-231. doi: 10.1007/s10877-019-00329-5. Epub 2019 Jun 3.