PMID- 31162982 OWN - NLM STAT- MEDLINE DCOM- 20210104 LR - 20210104 IS - 1744-5108 (Electronic) IS - 0167-6830 (Linking) VI - 39 IP - 2 DP - 2020 Apr TI - Contralateral Mueller's muscle-conjunctiva resection: a therapeutic option in thyroid eye disease patients with unilateral eyelid retraction. PG - 98-101 LID - 10.1080/01676830.2019.1619184 [doi] AB - Purpose: To evaluate pre- and post-operative marginal reflex distance 1 (MRD1) when conducting Mueller's muscle-conjunctiva resection (MMCR) on the normal eyelid of thyroid eye disease (TED) patients with unilateral eyelid retraction.Methods: This was a retrospective non-comparative case series. Medical records of TED patients with unilateral eyelid retraction, who underwent a contralateral MMCR from November 2015 to September 2017, were reviewed. Standard photographs of pre-operative, post-phenylephrine test and post-operative were measured for eyelid positions including MRD1, MRD2 and inter-palpebral fissure width. MMCR was indicated on the contralateral eyelid only in patients who had a cosmetically acceptable result from phenylephrine test and were willing to receive the operation on the normal eye.Results: Twelve TED patients who underwent MMCR on the normal eyelid were included in the study. Mean pre-operative MRD1 of retracted and normal eyelid were 5.7 mm (SD = 0.86) and 3.5 mm (SD = 0.65), respectively. Mean post-operative MRD1 of retracted and normal eyelid were 4.4 mm (SD = 0.76) and 4.1 mm (SD = 0.46), respectively. The asymmetry of MRD1 between eyes was significantly decreased from 2.1 mm (inter-quartile range (IQR) = 1.5-2.9 mm) pre-operatively to 0.3 mm (IQR = 0.1-0.7 mm) post-operatively (p = .002). None of these patients needed further eyelid correction surgery and there was no complication.Conclusions: In TED patients with unilateral eyelid retraction, using phenylephrine test on their normal eyes should be initiated. If eyelid position was satisfactorily equalized, performing MMCR on the normal eyelid is considered an effective alternative treatment with a predictable outcome. FAU - Saonanon, Preamjit AU - Saonanon P AUID- ORCID: 0000-0001-8033-0066 AD - Department of Ophthalmology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Chulalongkorn University, Bangkok, Thailand. FAU - Potita, Panida AU - Potita P AD - Department of Ophthalmology, Faculty of Medicine, King Chulalongkorn Memorial Hospital, The Thai Red Cross Society, Chulalongkorn University, Bangkok, Thailand. LA - eng PT - Journal Article PT - Video-Audio Media DEP - 20190604 PL - England TA - Orbit JT - Orbit (Amsterdam, Netherlands) JID - 8301221 SB - IM MH - Adult MH - Blepharoplasty/*methods MH - Conjunctiva/*surgery MH - Eyelid Diseases/*surgery MH - Female MH - Graves Ophthalmopathy/*surgery MH - Humans MH - Male MH - Middle Aged MH - Oculomotor Muscles/*surgery MH - Retrospective Studies OTO - NOTNLM OT - Eyelid retraction OT - Hering's phenomenon OT - Mueller's muscle-conjunctiva resection OT - marginal reflex distance OT - phenylephrine test OT - thyroid eye disease EDAT- 2019/06/05 06:00 MHDA- 2021/01/05 06:00 CRDT- 2019/06/05 06:00 PHST- 2019/06/05 06:00 [pubmed] PHST- 2021/01/05 06:00 [medline] PHST- 2019/06/05 06:00 [entrez] AID - 10.1080/01676830.2019.1619184 [doi] PST - ppublish SO - Orbit. 2020 Apr;39(2):98-101. doi: 10.1080/01676830.2019.1619184. Epub 2019 Jun 4.